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Vascular endothelial growth factor is essential to human reproduction.

Women's Health Weekly

| July 03, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 JUL 3 - (NewsRx.com & NewsRx.net) -- Vascular endothelial growth factor is essential to human reproduction.

According to recent research published in the journal Biology of Reproduction, "in this study, we examined the localization of vascular endothelial growth factor (VEGF) and the changes in VEGF mRNA expression in various regions of the oviduct in fertile women throughout the ovulatory cycle. Oviduct tissue was collected from 22 women undergoing laparoscopic tubal sterilization or hysterectomy for a benign gynecological condition. Oviduct sections were divided into isthmus, ampullary, and infundibular regions."

"Serial cross sections were analyzed for the presence of VEGF by specific immunohistochemical staining. The mucosal layer was isolated, and a semiquantitative reverse transcription polymerase chain reaction was performed. Immunohistochemical study revealed VEGF in the oviduct luminal epithelium, smooth muscle cells, and blood vessels within the oviduct," reported P.M. Lam and colleagues, Prince of Wales Hospital, Department of Obstetrics and Gynecology.

"VEGF mRNA expression in oviduct was the highest during the periovulatory stage, and the expression in the ampullary and infundibular regions was higher than that in the isthmus. There was a ...

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Source: HighBeam Research, Vascular endothelial growth factor is essential to human reproduction.

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