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Tumor-bed boost with brachytherapy can provide satisfactory local control.

Women's Health Weekly

| July 03, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 JUL 3 - (NewsRx.com & NewsRx.net) -- Tumor-bed boost with brachytherapy can provide satisfactory local control.

According to a study from England, "The results of treatment for 174 patients at high risk of local recurrence, referred for radiotherapy after conservative surgery for early breast cancer, are evaluated.

"Microscopic margin involvement, extensive carcinoma in situ, and vascular/lymphatic invasion were the main risk factors for local recurrence. Whole-breast irradiation (40 Gy in 15 fractions over 3 weeks) followed with a brachytherapy boost (Ir192 wire implant or PDR Ir192) of 25 Gy was applied," wrote H.C. Ulutin and colleagues, Cookridge Hospital, Yorkshire Regional Clinical Oncology Center.

"Median follow-up was 80 months. The actuarial 6-year overall survival rate was 91% and the within breast recurrence-free survival was 88%. The most common risk factor among those recurring within the breast was involved ...

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