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Information may help identify early environmental exposures that increase risk.

Women's Health Weekly

| July 03, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 JUL 3 - (NewsRx.com & NewsRx.net) -- Geographers and epidemiologists from the University at Buffalo, using geographic information systems (GIS) technology and life-course data from a cohort of breast cancer patients and controls in Western New York, have shown that women who developed breast cancer before menopause tend to cluster based on where they were born and where they lived at age of menarche (start of menstruation).

The clustering indicates that these women may have been exposed to something in the environment at those times in their lives that increased their risk of developing premenopausal breast cancer, said Daikwon Han, PhD, postdoctoral fellow in the UB Department of Social and Preventive Medicine and first author on the study.

There was less evidence of clustering of postmenopausal cancer cases, Han noted.

He presented the study results on June 12, 2003, at the annual meeting of the Society for Epidemiologic Research, held in Atlanta, Georgia.

"Researchers are moving more toward a life-course approach in studying the development of chronic disease," said Han. "At UB, we are developing spatial statistical methods to combine geographic information systems, mapping, and visualization with epidemiology to help identify patterns of disease."

Finding clustering of cancer patients based on where they were born and lived during early life is significant, said Peter Rogerson, PhD, UB professor of geography and a study ...

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