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2003 JUL 3 - (NewsRx.com & NewsRx.net) -- ETS-1 transcription factor expression is related to endometrial angiogenesis during the menstrual cycle.
According to published research from Japan, "ETS-1 has been identified as a transcription factor for angiogenesis, which is essential for the development and growth of the uterine endometrium. This characteristic prompted us to study whether ETS-1 functions as an angiogenic mediator in uterine endometrium. Immunohistochemical staining revealed that the localization of ETS-1 was similar to that of vascular endothelial cells."
"There was a significant correlation between microvessel counts and both ETS-1 histoscores and ets-1 mRNA levels in uterine endometrium. The ETS-1 histoscores and ets-1 mRNA levels increased in the proliferative phase, reached a peak during peri-ovulation and decreased in the secretory phase," described J. Fujimoto and colleagues, Gifu University, School of Medicine.
"Furthermore, the ETS-1 histoscores and ...