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Feasibility of edible vaccine development demonstrated.
2003 JUL 2 - (NewsRx.com & NewsRx.net) -- Researchers have demonstrated the feasibility of edible vaccine development.
According to recent research published in the journal Molecular Breeding, "Mannheimia haemolytica is the principal microorganism responsible for bovine pneumonic pasteurellosis, or shipping fever. We have previously expressed a fragment of leukotoxin, a major virulent factor of M. haemolytica A1, as a fusion protein with green fluorescent protein (GFP) in transgenic white clover and demonstrated that this antigen was immunogenic and elicited toxin neutralizing antibodies in rabbits."
"These previous results showed that using plants to produce M. haemolytica antigen for use as a vaccine against this disease is a viable strategy," said Raymond W. H. Lee and colleagues at the University of Guelph in Canada. "In this present study, we examined the stability of the truncated leukotoxin GFP-fusion protein (Lkt50-GFP) in field-grown transgenic white clover."
"Transgenic clover expressing Lkt50-GFP was clonally propagated and a confined field trial was established," reported the investigators. "Western immunoblotting showed that the level of Lkt50-GFP expression in field plants was the same as in transgenic plants ...
- New molecular breeding data have been reported by E. Dekeyser and co-authors.
- Newspaper article from: Life Science Weekly February 17, 2009 700+ words
...scientists writing in the journal Molecular Breeding report (see also Molecular Breeding). "For mapping applications, EST...colleagues published their study in Molecular Breeding (Discovery of species-wide EST...
- New molecular breeding research from H. Muranty et al outlined.
- Newspaper article from: Life Science Weekly March 31, 2009 700+ words
...research published in the journal Molecular Breeding, "Powdery mildew (Blumeria graminis...Muranty and colleagues (see also Molecular Breeding). The researchers concluded...colleagues published their study in Molecular Breeding (Two stable QTL involved in adult...
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- Newspaper article from: Life Science Weekly August 5, 2008 700+ words
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- 'India's vaccine development sector to lead biopharma biz'.
- News wire article from: PTI - The Press Trust of India Ltd. December 27, 2005 700+ words
'India's vaccine development sector to lead biopharma biz...India as the future site for vaccine development," a study undertaken by...favourite destination for vaccine development," he said. "It's a win...
- Reports outline molecular breeding research from M.P. Fernandez and colleagues.
- Newspaper article from: Life Science Weekly September 30, 2008 700+ words
...scientists writing in the journal Molecular Breeding report (see also Molecular Breeding). "In the present study, flanking...colleagues published their study in Molecular Breeding (Characterization of sequence polymorphisms...
- Reports outline molecular breeding research from Murdoch University.
- Newspaper article from: Life Science Weekly September 2, 2008 700+ words
...research published in the journal Molecular Breeding, "A new mutation at the acetohydroxyacid...colleagues, Murdoch University (see also Molecular Breeding). The researchers concluded...colleagues published their study in Molecular Breeding (A mutation at the Ala122 position...
- Research on molecular breeding reported by A. Patocchi et al.
- Newspaper article from: Life Science Weekly November 17, 2009 700+ words
...from Wadenswil, Switzerland, "Molecular breeding for pathogen resistance faces two...Patocchi and colleagues (see also Molecular Breeding). The researchers concluded...the results of their research in Molecular Breeding (Towards improvement of marker assisted...
- Reports summarize molecular breeding research from Catholic University.(Report)
- Newspaper article from: Life Science Weekly November 18, 2008 700+ words
...research published in the journal Molecular Breeding, "In this paper, 10 mutations...Catholic University (see also Molecular Breeding). The researchers concluded...colleagues published their study in Molecular Breeding (The integration of mutant loci...
Source: HighBeam Research, Feasibility of edible vaccine development demonstrated.