AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
J8-and diphtheria toxoid antibodies help protect against group A strep.
2003 JUL 2 - (NewsRx.com & NewsRx.net) -- J8-and diphtheria toxoid-specific antibodies contribute to protection against group A streptococcus.
"A conformationally constrained, minimally conserved peptide from the M protein of group A streptococcus (GAS) has been defined. It consists of 12 amino acids from the C-repeat region within a non-M protein helix-forming sequence and is referred to as 'J8.' Here, we investigate the immunogenicity of a J8-diphtheria toxoid (DT) conjugate adjuvanted with the human-compatible adjuvants, SBAS2 and alum, and demonstrate that it is capable of inducing opsonic antibodies and can protect outbred mice from virulent challenge," scientists writing in the Journal of Infectious Diseases report.
"In a range of experiments, protection correlated with the titer of J8-specific antibodies and not with the induction of J8-specific T cells," wrote Michael R. Batzloff and collaborators at the Queensland Institute of Medical Research in Australia. "However, DT-specific antibodies (as well as J8-specific antibodies) were shown to stain the surface of fixed GAS and to be capable of opsonizing live ...
- Meningococcal polysaccharide-diphtheria toxoid conjugate vaccine is safe in...
- Newspaper article from: Vaccine Weekly January 29, 2003 700+ words
...meningitidis-diphtheria toxoid conjugate vaccine...the Journal of Infectious Diseases (Safety, reactogenicity...polysaccharide-diphtheria toxoid conjugate vaccine...adults. Journal of Infectious Diseases 2002;186(12...
- J8-and diphtheria toxoid antibodies help protect against group A strep.
- Newspaper article from: Biotech Week July 2, 2003 700+ words
...of a J8-diphtheria toxoid (DT) conjugate...Journal of Infectious Diseases report...concluded, "Diphtheria toxoid may be an...Journal of Infectious Diseases (Protection...with J8-diphtheria toxoid: Contribution...
- Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine...
- Newspaper article from: Travel Medicine Advisor November 1, 2005 700+ words
Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis...children, Adacel contains diphtheria toxoid and one of the pertussis...fimbriae types 2 and 3, 2 Lf of diphtheria toxoid, and 5 Lf of tetanus toxoid...
- Pharmacology Update: Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular...
- Magazine article from: Internal Medicine Alert September 29, 2005 700+ words
...Pharmacology Update Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine...Adacel™ contains diphtheria toxoid and one of the pertussis components...fimbriae types 2 and 3, 2 Lf of diphtheria toxoid, and 5 Lf of tetanus toxoid. The...
- FDA Approval of Expanded Age Indication for a Tetanus Toxoid, Reduced...
- Magazine article from: MMWR. Morbidity and Mortality Weekly Report Anonymous April 17, 2009 700+ words
...for the tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine...use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccines...use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine...
- ACIP: add Tdap to routine shots.(News)(Advisory Committee on Immunization...
- Magazine article from: Family Practice News Tucker, Miriam E. August 1, 2005 700+ words
...meeting. Two Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine...sequence. Both vaccines contain diphtheria toxoid. Here, concerns about increased...about the same amounts of tetanus and diphtheria toxoid as does Tdap--can be administered...
- Two new vaccines for 2006.(meningococcal conjugate vaccine)(tetanus/diphtheria...
- Newspaper article from: Pediatrics for Parents July 1, 2005 700+ words
...entering college or the military should also consider receiving the vaccination. The second vaccine is the new tetanus/diphtheria toxoid/acellular pertussis vaccine for adolescents. This vaccine is abbreviated Tdap as opposed to DtaP, which is the vaccine...
- Good news for Sanofi-Aventis' Menactra.(Menactra meningococcal polysaccharide...
- Newspaper article from: Pharma Marketletter October 4, 2004 700+ words
...Advisory Committee has voted unanimously to recommend approval of Sanofi-Aventis' Menactra meningococcal polysaccharide diphtheria toxoid conjugate vaccine for protection against invasive meningococcal disease in adolescents and adults aged 11-15 years...
