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Study will evaluate recombinant canarypox HIV-1 vaccine in IV drug users.
2003 JUL 2 - (NewsRx.com & NewsRx.net) -- A Harvard School of Public Health researcher will be conducting a study to evaluate the efficacy of a recombinant canarypox HIV-1 vaccine in IV drug users.
S. Dhalla announced the clinical trial at the 36th Annual Society of Epidemiological Research (SER) Meeting held in Atlanta, Georgia, June 11-14, 2003.
"The efficacy of a recombinant canarypox ALVAC-vCP205 HIV-1 vaccine will be studied in an initially seronegative group of IV drug users, a disadvantaged community of individuals. Excluded will be those with mental illness, history of malignancy or immunodeficiency, pregnancy, active tuberculosis, and recent receipt of blood products or a vaccine," Dhalla said.
Over a period of three years, study subjects' risk-taking behaviors, immunogenicity (humoral and cell-mediated), and short-term adverse effects (related/unrelated to vaccination) will be assessed.
"Clinical equipoise is crucial in a randomized preventive trial, and strict ethical principles will be followed," Dhalla said.
The vaccine or placebo (0.5 ml of either) "will be administered as an IM injection into the left arm at 0, 1, 3, and 6 ...
- Study will evaluate recombinant canarypox HIV-1 vaccine in IV drug users.
- Newspaper article from: Biotech Week July 2, 2003 700+ words
...evaluate the efficacy of a recombinant canarypox HIV-1 vaccine in IV drug users. S. Dhalla announced...2003. "The efficacy of a recombinant canarypox ALVAC-vCP205 HIV-1...initially seronegative group of IV drug users, a disadvantaged...
- HIV seroprevalence rate among IV drug users in New York stabilized.
- Newspaper article from: AIDS Alert April 1, 1989 700+ words
HIV seroprevalence rate among IV drug users in New York stabilized After a period...New York City. However, it shows that IV drug users are adopting practices that reduce...our prevention efforts." More than 650 IV drug users studied Des Jarlais was one of the...
- AIDS FIGHT FOCUSING ON IV DRUG USE AMONG MINORITIES
- Newspaper article from: The Boston Globe Gregory Witcher, Globe Staff May 1, 1987 700+ words
...percent of all Hispanics with the disease are IV drug users, compared with 5 percent of all whites...were born to minority women who were either IV drug users or their sex partners were IV drug users. Infants can become infected by their...
- HTLV infection linked to IV drug abuse. (human T-cell lymphotropic virus,...
- Newspaper article from: AIDS Alert June 1, 1992 700+ words
...same ways as HIV -- is more prevalent among IV drug users than any other group at risk for HIV infection...HTLV-II is much more common than HTLV-I in IV drug users.(1) For 3,217 IV drug users entering 20 drug treatment centers, the...
- AIDS `second wave' told // Tax hike asked to help IV drug users
- Newspaper article from: Chicago Sun-Times Richard Roeper; Tom Brune June 24, 1988 700+ words
...department found an 82 percent increase in IV drug-related AIDS cases reported this year compared with previous years. The number of IV drug-related AIDS cases is still relatively...9 percent can be attributed solely to IV drug use. Turnock said that 73 of the 394...
- STATE CARE SCARCE FOR IV DRUG USERS MANY MORE ADDICTS, WORRIED BY AIDS SPREAD,...
- Newspaper article from: The Boston Globe Sean Murphy, Contributing Reporter January 10, 1988 700+ words
...Massachusetts for an estimated 40,000 intravenous, or IV, drug users. Driven by the fear of AIDS, addicts are...spreading the AIDS virus to a growing number of IV drug abusers. "The IV drug user's potential for spreading AIDS is explosive...
- HIV and IV drug abuse: AIDS poses a growing threat to addicts, and thus to...
- Magazine article from: Science News Fackelmann, Kathy A. March 18, 1989 700+ words
HIV and IV Drug Abuse When a National Research Council...partners and their unborn children. Many IV drug users share needles, and a needle contaminated...readily passes it on. "Infection among IV drug abusers is continuing to occur at a very...
- Finding a venipuncture site in an IV drug user: drawing blood from addicts with...
- Magazine article from: Clinical Advisor Calhoun, Bridget C. June 1, 2006 700+ words
...social history included 30-plus years of IV drug use, with heroin being his drug of choice...proved to be a challenge. Decades of IV drug use had severely thickened his veins...potential complications. Manifestations of IV drug use It is important that all clinicians...
