High TnT concentration denotes myocyte injury and poor outcome despite treatment to lower BNP in congestive heart failure. (ECHO).(troponin T, brain natriuretic peptide )(Brief Article)

A mall study to clarify the roles of troponin T (TnT) and brain natriuretic peptide (BNP) in decompensated congestive heart failure (CHF) has suggested that TnT is a marker of myocyte injury and not of CHF.

In patients with decompensated CHF and congested lungs baseline plasma BNP values for were high (mean 927.3 (SD 672.0) pg/ml, range 105-3121 pg/ml). However, serum TnT was either significantly raised (0.02 ng/ml)--in 22 (63%) of patients (group 1) or <0.02 ng/ml in 13 patients (37%, group 2). BNP concentration in the two groups was also significantly higher in group I than group 2 (1114.3 (708.4) v 610.8 (477.9) pg/ml) and remained so, even once lung congestion had …