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2003 JUN 19 - (NewsRx.com & NewsRx.net) -- Physical exercise reduces risk of breast cancer in Japanese women.
According to a study from Japan, "To evaluate the effects of physical exercise on breast cancer risk, a large-scale case-referent study of 2376 incident breast cancer cases and 18,977 non-cancer referents was conducted using data from the hospital-based epidemiologic research program at Aichi Cancer Center (HERPACC).
"To adjust appropriately for possible confounders, we examined the effects within subgroups of the study population. The multivariable-adjusted odds ratio (OR) was 0.81 (95% confidence interval (CI): 0.69-0.94) for twice a week or more regular exercise," wrote K. Hirose and colleagues, Aichi Cancer Center, Research Institute.
"We observed a decreased risk of breast cancer for women who regularly exercised for health twice a week or more, irrespective of menopausal status, and were able to detect greater risk reductions within particular subgroups, including women who were parous, without a family history, or non-drinkers," the researchers stated.
"Among premenopausal women, a particularly strong protective effect of physical exercise was observed (OR = 0.57, 95% CI: 0.28-1.15) for those women whose body mass index (BMI) was high (BMI greater than or equal to 25).
"In contrast, risk reduction was found (OR = 0.71, 95% ...