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Elderly adults mount strong immune response to influenza vaccination.

Vaccine Weekly

| June 11, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Elderly adults vaccinated against influenza mounted strong, protective immune responses, according to a report in the Journal of Clinical Immunology.

According to recent research from Poland, "The purpose of this study was to assess the serum antibody responses to both the hemagglutinin and the neuraminidase antigens of inactivated influenza vaccine in 45 elderly and 28 younger adults."

"After vaccination, antihemagglutinin antibody levels increased significantly and mean fold increases ranged from 2.8 to 22.0," reported Lidia B. Brydak and colleagues at the National Institute of Hygiene in Warsaw. "Seroprotection rates were between 42.2 and 91.1% one month after vaccination and 15.6 and 84.4% five months afterward."

The investigators found, "Seroresponse rates ranged from 42.2 to 91.1% one month after vaccination and 15.6 to 82.2% 5 months afterward. After vaccination antineuraminidase antibody levels increased significantly and mean fold increases ranged from 3.6 to 12.3. Significantly higher antibody responses to both hemagglutinin and neuraminidase were ...

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Source: HighBeam Research, Elderly adults mount strong immune response to influenza vaccination.

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