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European patent issued; DNA vaccine research contract granted.

Vaccine Weekly

| June 11, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Vical Incorporated (NASDAQ:VICL) announced that European Patent EP0737750, entitled "Expression of Exogenous Polynucleotide Sequences in a Vertebrate," has been granted to Vical.

This patent is part of a family of patents based on the company's discovery that tissues can take up polynucleotides, such as DNA or RNA, without the use of viral delivery vehicles and subsequently express the proteins encoded by the polynucleotides. Vical holds multiple issued U.S. patents covering various aspects of this key discovery.

The new patent claims medicinal compositions which contain cationic lipids and polynucleotides and which elicit an immune response against the proteins encoded by the polynucleotides. The new patent covers a range of applications of the company's core DNA delivery technology, including cationic lipid-formulated, gene-based immunotherapeutics such as Vical's clinical-stage ...

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