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ASCO assesses updated trial results on Arimidex use for early breast cancer.
2003 JUN 12 - (NewsRx.com & NewsRx.net) -- The Technology Assessment Working Group of the American Society of Clinical Oncology (ASCO) voted unanimously to support and maintain their recommendation issued last year regarding Arimidex (anastrozole) Tablets use in postmenopausal women with hormone receptor-positive early breast cancer, as posted on the website of the Journal of Clinical Oncology ( www.jco.org ), and to be published in the July 1, 2003, issue.
The Working Group indicated that the 47-month follow-up data from the Arimidex early breast cancer trial (ATAC - Arimidex, Tamoxifen, Alone or in Combination) provide "a greater level of assurance, in terms of both toxicity and efficacy, for physicians and their patients who are considering the use of anastrazole (Arimidex) in the adjuvant setting."
They noted that the updated data continue to support their previous recommendation that Arimidex be considered for postmenopausal women with hormone receptor-positive early breast cancer who may be at high risk for some of the side effects associated with tamoxifen, such as blood clots and stroke. Arimidex is the only hormonal drug other than tamoxifen that has been approved for use in the adjuvant setting.
The adjuvant treatment indication for Arimidex was approved in September 2002 by the U.S. Food and Drug Administration (FDA) for treatment following surgery with or without chemotherapy and radiation in postmenopausal women with hormone receptor-positive early breast cancer. The effectiveness of Arimidex is based on an analysis of recurrence-free survival from the ongoing Arimidex early breast cancer trial (ATAC) in patients taking Arimidex as treatment ...
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Source: HighBeam Research, ASCO assesses updated trial results on Arimidex use for early breast...