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EMBRYONIC STEM CELLS: Parthenogenesis Yields Primate Stem Cells.

Cell Therapy News

| May 01, 2003 | COPYRIGHT 2003 BCC Research. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Primate embryos derived parthenogenetically can give rise to embryonic stem cells, according to a study by Jose Cibelli from Advanced Cell Technology (One Innovation Dr., Worcester, MA 01650; Tel: 508/756-1212, Fax: 508/756-0931; Website: www.advancedcell.com) (Cibelli has since moved to Michigan State University) along with colleagues from Millennium Pharmaceuticals (640 Memorial Dr., Cambridge, MA 02139; Tel: 617/679-7000, Fax: 617/374-9379; Website: www.mlnm.com) and several academic institutions. The study was recently published in the Proceedings of the National Academy of Sciences.

Parthenogenesis is a process in which an egg develops into an embryo without fertilization by sperm. Though parthenogenesis is fairly common in nature, it does not occur in mammals. However, oocytes can be tricked by various methods into undergoing division, which will result in aborted development of an embryo.

Cibelli and his colleagues were able to get parthenogenetic embryos ...

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