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Hormonal function was normal after ovarian transplantation in rats.
2003 JUN 5 - (NewsRx.com & NewsRx.net) -- Hormonal function was normal after ovarian transplantation in rats.
"The purpose of the study was to determine the feasibility of preserving ovarian function after heterotopic transplantation by means of microvascular anastomosis of the transplanted vascular pedicles to a set of preselected vessels," scientists in the United States report.
"Six groups of 10 Sprague-Dawley inbred rats were used in this study. Group I underwent bilateral ovariectomy operation and served as the ovariectomy control.
"Group II underwent bilateral ovariectomy followed by heterotopic isogenic ovarian implantation," wrote D.T.W. Chiu and colleagues, Columbia University, College Physicians & Surgeons.
"Group III underwent bilateral ovariectomy and isogenic heterotopic ovarian transplantation by means of microvascular anastomosis. Group IV served as the laparotomy sham-operated control.
"Group V served as the ovarian donor for group II. Group VI served as the donor of the ovarian-kidney vascular pedicle complex for Group III," the researchers stated.
"Postoperative ovarian estradiol levels were measured, and histological characteristics were elucidated in Groups I, II, III, and IV.
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