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Bordetella pertussis protein pertactin induces immune response.
2003 JUN 4 - (NewsRx.com & NewsRx.net) -- The Bordetella pertussis protein pertactin induced type-specific antibodies.
"Divergence has been found between Bordetella pertussis vaccine strains and circulating strains. Polymorphism in pertactin (Prn) is essentially limited to region 1, which is made up of repeats. Today, the three most prevalent Prn variants are Prn1-3," investigators in Finland and the Netherlands report.
"Vaccine strains produce Prn1, whereas Prn2 is the predominant type found in circulating strains," said Qiushui He and colleagues at the National Public Health Institute in Finland and the National Institute of Public Health and the Environment in the Netherlands. "We investigated how variation in region 1 affects the production of human serum antibodies. Individuals infected by Prn2 strains had significantly fewer antibodies to Prn1 did than those infected by Prn3 strains and those immunized with a booster dose of acellular vaccines containing Prn1. Moreover, in contrast to vaccine recipients and subjects infected by Prn3 strains, individuals infected by Prn2 strains had hardly any antibodies specific to ...
- Bordetella pertussis acts as adjuvant and inhibitor of immune responses.
- Newspaper article from: Drug Week April 23, 2004 700+ words
...formalin-inactivated Bordetella pertussis (Bp) augmented...Norwegian Institute of Public Health. "This inhibitory...study in Vaccine (Bordetella pertussis can act as adjuvant...Norwegian Institute of Public Health, PO Box 4404 Nydalen...
- Bordetella pertussis, Finland and France.(DISPATCHES)(infectious diseases...
- Magazine article from: Emerging Infectious Diseases Caro, Valerie Elomaa, Annika Brun, Delphine Mertsola, Jussi He, Qiushui Guiso, Nicole June 1, 2006 700+ words
...clinical isolates of Bordetella pertussis recovered since...a considerable public health problem worldwide...of the disease, Bordetella pertussis, are of some concern...of the National Public Health Institute (Turku...
- Rapid identification of Bordetella pertussis pertactin gene variants using...
- Magazine article from: Emerging Infectious Diseases Makinen, Johanna Viljanen, Matti K. Mertsola, Jussi Arvilommi, Heikki He, Qiushui November 1, 2001 700+ words
...have been characterized in Bordetella pertussis strains isolated in Europe...research. ********** Bordetella pertussis is the causative agent of...Reference Laboratory, National Public Health Institute, Turku, Finland...
- Is Bordetella pertussis clonal? (Papers)
- Magazine article from: British Medical Journal Khattak, M.N. Matthews, R.C. Burnie, J.P. March 28, 1992 700+ words
...Introduction Previous work based on examining isolates of Bordetella pertussis by analysing allelic variation in structural genes encoding...following isolates were examined: 67 isolates from 14 public health laboratories and 16 district general hospitals throughout...
- The use of TaqMan PCR assay for detection of Bordetella pertussis infection...
- Magazine article from: Archives of Pathology & Laboratory Medicine Chan, Edward L. Antonishyn, Nick McDonald, Ryan Maksymiw, Tara Pieroni, Peter Nagle, Evelyn Horsman, Greg B. February 1, 2002 700+ words
...coughing; mild systemic complaints; and lymphocytosis. Bordetella pertussis does not survive well in the environment and is most likely...not only for the treatment of the patient, but also for public health purposes to prevent the spread of the infection and to...
- Toxin from Bordetella pertussis offers promise for antigen delivery.
- Newspaper article from: Vaccine Weekly August 4, 2004 700+ words
...The adenylate cyclase toxin from Bordetella pertussis is a novel promising vehicle for...recent research from France, "Bordetella pertussis secretes an adenylate cyclase toxin...The adenylate cyclase toxin from Bordetella pertussis - a novel promising vehicle for...
- bvgR expression in Bordetella pertussis analyzed.
- Newspaper article from: Proteomics Weekly January 5, 2004 700+ words
...the analysis of bvgR expression in Bordetella pertussis in a recent issue of the Journal...research from the United States, "Bordetella pertussis, the causative agent of whooping...Analysis of bvgR expression in Bordetella pertussis. J Bacteriol, 2003;185(23...
- Changes in predominance and diversity of genomic subtypes of bordetella...
- Magazine article from: Emerging Infectious Diseases Hardwick, Terri Hawes Cassiday, Pamela Weyant, Robbin S. Bisgard, Kristine M. Sanden, Gary N. January 1, 2002 700+ words
...Pulsed-field gel electrophoresis (PFGE) of Bordetella pertussis chromosomal DNA fragments generated by Xbal restriction...cough, is an acute respiratory disease caused by Bordetella pertussis. Before pertussis vaccine was introduced in...
- Bordetella pertussis Goes to College.
- Magazine article from: Family Practice News Wang, Jennifer M. October 15, 2000 700+ words
Bordetella pertussis was responsible for 8% of illnesses with prolonged cough in 319 University of Washington students. Of the 26 B. pertussis cases...
- Bordetella pertussis isolates, Finland.(Letters)(Letter to the Editor)
- Magazine article from: Emerging Infectious Diseases Makinen, Johanna Mertsola, Jussi Mooi, Frits R. Van Amersfoorth, Shirley Arvilommi, Heikki Viljanen, Matti K. He, Qiushui January 1, 2005 700+ words
To the Editor: Pertussis, or whooping cough, is a highly contagious respiratory disease in humans caused by Bordetella pertussis. Reemergence of pertussis has been observed in many countries with high vaccination coverage. In the United States...
Source: HighBeam Research, Bordetella pertussis protein pertactin induces immune response.