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Nasal vaccine delivery platform data presented at vaccine conference.

Vaccine Weekly

| June 04, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Carrington Laboratories, Inc., (CARN) announced that results of an initial study sponsored by its subsidiary DelSite Biotechnologies, Inc., were presented at the 6th Annual Conference of Vaccine Research in Arlington, Virginia.

The study evaluated the effect of GelVac, a new nasal vaccine delivery platform, on antigen nasal residence time and immune response in a mouse model.

Two different types of antigens were used to evaluate immune response, a soluble protein antigen (diphtheria toxin mutant DT-CRM) and a viral subvirion antigen (inactivated subvirion split influenza virus).

Groups of mice were inoculated intranasally two or three times, 10 days apart, with GelVac formulations containing antigen compared to antigen alone, and mucosal antibody (IgA) and systemic antibody (IgG) titers were then ...

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Source: HighBeam Research, Nasal vaccine delivery platform data presented at vaccine conference.

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