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Infection in kidney transplant patient caused by novel mutants of hepatitis B.
2003 JUN 4 - (NewsRx.com & NewsRx.net) -- An infection in a renal transplant recipient caused by novel mutants of hepatitis B virus occurred despite protective anti-hepatitis B surface antibodies.
"A renal transplant recipient became persistently positive for hepatitis B virus (HBV) despite pre-existing anti-hepatitis B surface (HBs) antibodies," researchers in Germany report.
"The antigenicity and immunogenicity of wild-type (wt) and mutant HBs antigens (Ags) were compared," stated Mengji G. Lu and Thomas Lorentz at the Universitatsklinikum Essen. "In contrast to wt HBsAg, genetic vaccination with mutant HBsAgs did not induce anti-HBs. Thus, mutations within HBsAg may enable HBV to escape immunological control."
Lu and Lorentz published their study in the Journal ...
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Source: HighBeam Research, Infection in kidney transplant patient caused by novel mutants of...