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Four hepatitis B prevention programs evaluated.

Vaccine Weekly

| June 04, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Four hepatitis B prevention programs in four states in the U.S. were evaluated for effectiveness.

According to recent research from the United States, "During 1992-2000, the authors studied compliance with perinatal hepatitis B prevention recommendations including vaccination of household contacts, at four metropolitan sites in Connecticut, Georgia, Texas, and Michigan. Demographic and hepatitis B-related knowledge, attitudes, practices, and barrier data were collected on pregnant women testing positive for hepatitis B surface antigen and on their infants, children, and household and sexual contacts."

"Generalized estimating equations with repeated measures in a multivariable model were used to obtain adjusted relative risks of household noncompliance," reported Gary L. Euler and collaborators at the Centers for Disease Control and Prevention. "In 1,458 households studied, 1,490 infants, and 3,502 other contacts were identified. Among infants, vaccination start/finish rates were 92%/72%, and 73% were serotested postvaccination. Prevaccination serotesting rates among contacts were 22% pre-enrollment and 47% post-enrollment, Among 2,519 contacts whose immunity status was susceptible or unknown, the vaccination start/finish rate was 45%/41%."

"Site-specific adjusted relative risks of household noncompliance compared with Texas were 2.14 (Michigan), 1.96 (Georgia), and 1.30 (Connecticut)," the ...

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