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Vaccinia virus vaccine stable whether diluted or undiluted.
2003 JUN 4 - (NewsRx.com & NewsRx.net) -- The stability of the vaccinia virus vaccine Dryvax was similar whether it was stored diluted or undiluted.
According to a study from the United States, "The stability of Dryvax vaccine was examined to determine whether diluted vaccine could be used over an extended period, thereby increasing the number of available doses."
"Stability parameters that we evaluated include dilution (undiluted, diluted 1:5, and diluted 1:10), diluent (original Dryvax diluent, new Dryvax diluent, and phosphate-buffered saline), and temperature (refrigerator temperature and room temperature)," reported Frances K. Newman and colleagues St. Louis University and the EMMES Corporation.
The authors continued, "Storage of reconstituted Dryvax vaccine at room temperature, regardless of dilution or diluent, resulted in a significantly greater decrease in titer than did storage at refrigerator temperature. At refrigerator temperature, the ...
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Source: HighBeam Research, Vaccinia virus vaccine stable whether diluted or undiluted.