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Hepatitis A vaccine does not affect course of HIV.

Vaccine Weekly

| June 04, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Hepatitis A vaccination did not affect the course of HIV infection in HIV-positive patients.

"The safety and immunogenicity of inactivated hepatitis A (HepA) vaccine was assessed in 133 hepatitis A virus-seronegative, human immunodeficiency virus (HIV)-infected adults," scientists in the United States report.

"Patients were randomly assigned to receive, in a blinded fashion, either two doses of vaccine (1,440 enzyme-linked immunosorbent assay units) or placebo six months apart," said Carol A. Kemper and collaborators at Stanford University, the University of California-San Diego, University of Pennsylvania, and GlaxoSmithKline Biologicals. "Seroconversion at month nine was observed in 68% of those with CD4 cell counts greater than or equal to200 cells/mm[superscript]3 but in only 9% of those with lower CD4 cell counts (p=0.004). HepA vaccine was well tolerated and had no effect on the course of ...

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Source: HighBeam Research, Hepatitis A vaccine does not affect course of HIV.

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