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2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Hepatitis A vaccination did not affect the course of HIV infection in HIV-positive patients.
"The safety and immunogenicity of inactivated hepatitis A (HepA) vaccine was assessed in 133 hepatitis A virus-seronegative, human immunodeficiency virus (HIV)-infected adults," scientists in the United States report.
"Patients were randomly assigned to receive, in a blinded fashion, either two doses of vaccine (1,440 enzyme-linked immunosorbent assay units) or placebo six months apart," said Carol A. Kemper and collaborators at Stanford University, the University of California-San Diego, University of Pennsylvania, and GlaxoSmithKline Biologicals. "Seroconversion at month nine was observed in 68% of those with CD4 cell counts greater than or equal to200 cells/mm[superscript]3 but in only 9% of those with lower CD4 cell counts (p=0.004). HepA vaccine was well tolerated and had no effect on the course of ...
Source: HighBeam Research, Hepatitis A vaccine does not affect course of HIV.