AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Vaccination against hepatitis A elicits humoral and cellular immune responses.
2003 JUN 4 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Vaccination against hepatitis A stimulates release of both interferon-gamma and interleukin-10, according to a report in Pharmacotherapy.
Mary S. Hayney and colleagues at the University of Wisconsin in the United States evaluated cytokine production in 25 healthy adults immunized with an inactivated hepatitis A vaccine. Levels of interferon-gamma (IFN-gamma) and interleukin-10 (IL-10) were measured in sera on the day of vaccination and 2, 5, 7, 10, and 28 days afterward.
"Production of IFN-gamma and IL-10 by peripheral blood mononuclear cells stimulated in culture with hepatitis A virus was measured by enzyme-linked immunosorbent assay," reported the researchers.
The highest levels found for both IFN-gamma and IL-10 were on the tenth day after immunization (22.35 pg/mL and 11.75 pg/mL, respectively) and were significantly greater than baseline values (7.35 pg/mL and 1.00 pg/mL, respectively; p
A significant correlation was found between the IL-10:IFN-gamma ratio found on day 10 and the levels of anti-hepatitis A antibody levels on day 28 (p
"Both IFN-gamma and IL-10 are produced in response to ...
- IFN-alpha enhances CD154 expression, but needs IL-12 to upregulate IFN-gamma.
- Newspaper article from: Immunotherapy Weekly July 2, 2003 700+ words
...research from Japan, "Like IL-12, IFN-alpha has been shown to play...immobilized anti-CD3 with or without IFN-alpha and IL-12, in complete absence of...enhanced it in the presence of IL-12. Accordingly, IFN-alpha enhanced IL-12Rbeta2...
- The relationship between serum levels of total IgE, IL-18, IL-12, IFN-[gamma]...
- Magazine article from: Mediators of Inflammation Aral, Murat Arican, Ozer Gul, Mustafa Sasmaz, Sezai Kocturk, Sumeyra Alkis Kastal, Ummugulsum Ekerbicer, Hasan Cetin January 1, 2006 700+ words
...completely clarified yet. Serum levels of total IgE, IL-18, IL-12, IFN-[gamma] and the relationship between these parameters...the severity. Serum levels of total IgE, IL-18, IL-12, IFN-[gamma] and the relationship between these parameters...
- Resistance may occur with IL-12, IFN-gamma, NO produced by NK and macrophages.
- Newspaper article from: Biotech Week June 18, 2003 700+ words
...macrophages and NK cells, by means of IL-12, IFN-gamma, and NO. A study from...examined the role of the cytokines IFN-gamma and IL-12 in the model of acute babesiosis...cytokine responses. Levels of IFN-gamma and IL-12 in serum increased 24 h after...
- Induction of a soluble anti-HIV-1 factor (s) with IFN-[gamma], IL-10, and...
- Magazine article from: American Journal of Infectious Diseases Rodriguez, Jose W. Pagan, Nat O. Ocasio, Maria C. Rios, Zilka Cubano, Luis A. Boukli, Nawal M. Otero, Miguel Hunter, Robert Nair, Madhavan P. Rios-Olivares, Eddy October 1, 2007 700+ words
...associated with induction of IFN-[gamma], MIP-1[alpha...production, but inhibition of IL-10. Furthermore, this...activator (ATF-uPA), IL-16, antithrombin III...peroxiredoxin, TNF-[alpha], IL-13, IFN-[gamma]/[alpha...
- Local Secretion of IFN-gamma Induces an Antitumor Response: Comparison Between...
- Newspaper article from: Immunotherapy Weekly August 23, 1999 700+ words
...Response: Comparison Between T Cells Plus IL-2 and IFN-gamma Transfected Tumor Cells." Journal...IFN-gamma) as delivery systems of IFN-gamma. Treatment with TIL-IL-2 or irradiated MCA-105/IFN-gamma induced a similar reduction in...
- IFN-gamma induced products repress transcription of Th2-determining IL-4.
- Newspaper article from: Proteomics Weekly February 24, 2003 700+ words
...host immunity to pathogens. IL-4 and IFN-gamma are the signature cytokines...described. We show here that IFN-gamma directly suppresses IL-4 gene expression. IRF...published their study in Immunity (IFN-gamma represses IL-4 expression via IRF-1...
- Transplantation with IL-2 And IFN-Alpha Activated Bone Marrow Cells Followed By...
- Newspaper article from: Blood Weekly March 29, 1999 700+ words
...Immunotherapy "Transplantation with IL-2 And IFN-Alpha Activated Bone Marrow Cells...leukemia were transplanted with IL-2 and IFN-a activated bone marrow followed...was given following infusion of IL-2 and IFN-(alpha) activated bone marrow...
- Transplantation with IL-2 And IFN-Alpha Activated Bone Marrow Cells Followed By...
- Newspaper article from: Immunotherapy Weekly March 29, 1999 700+ words
...Immunotherapy "Transplantation with IL-2 And IFN-Alpha Activated Bone Marrow Cells...leukemia were transplanted with IL-2 and IFN-a activated bone marrow followed...was given following infusion of IL-2 and IFN-(alpha) activated bone marrow...