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Phase I smallpox vaccine clinical trial completed.
2003 MAY 14 - (NewsRx.com & NewsRx.net) -- Computer Sciences Corporation (CSC) announced that DynPort Vaccine Company LLC (DVC), a joint venture between CSC and Porton International, a vaccine development company focused on biodefense vaccines, has completed phase I testing of the safety and immunogenicity of an improved cell-cultured smallpox vaccine (CCSV).
In this trial, 100% of 350 volunteers exhibited a positive response to either the CCSV or the historic calf lymph-produced smallpox vaccine (Dryvax). However, the incidence of vaccine-related fatigue, application site rash, increased temperature, headache, lymphangitis and nausea was at least 8% less common for volunteers receiving CCSV than Dryvax.
DVC develops biodefense vaccines for the Department of Defense (DoD) through the Joint Vaccine Acquisition Program (JVAP). This is accomplished through the design and implementation of strategies for advanced development by partnering with government and industry.
"Protection against potential future biological attacks continues to be a key concern of our nation's leaders," said DVC president Terry Irgens. "The availability of adequate stocks of effective and safe smallpox vaccine that meets modern manufacturing standards is of paramount importance. At ...
- CSC Joint Venture DynPort Completes Phase I Smallpox Vaccine Clinical Trial.
- Press release article from: PR Newswire April 17, 2003 700+ words
...and immunogenicity of an improved cell-cultured smallpox vaccine (CCSV). In this trial, 100% of 350 volunteers exhibited...either the CCSV or the historic calf lymph-produced smallpox vaccine (Dryvax(R)). However, the incidence of vaccine...
- CSC joint venture DynPort completes Phase I smallpox vaccine clinical trial.
- News wire article from: Asia Africa Intelligence Wire April 17, 2003 700+ words
...and immunogenicity of an improved cell-cultured smallpox vaccine (CCSV). In this trial, 100% of 350 volunteers exhibited...either the CCSV or the historic calf lymph-produced smallpox vaccine (Dryvax). However, the incidence of vaccine...
- Q&A handout: smallpox vaccine during pregnancy.
- Newspaper article from: Hospital Infection Control July 1, 2003 700+ words
...pregnant women are vaccinated with the smallpox vaccine, are there any special risks to the...reported in the United States. When smallpox vaccine was routinely given in the United...to pregnant women who have received smallpox vaccine at increased risk for birth defects...
- US Government Grants Additional Award to Bavarian Nordic for Development Of...
- Press release article from: PR Newswire September 25, 2003 700+ words
...BN as a safe third-generation smallpox vaccine. The award was granted to Bavarian...appropriate milestones of Part A in the smallpox vaccine development program, and the potential...BN as a safe third-generation smallpox vaccine in Phase ll clinical studies in healthy...
- US Government grants additional award to Bavarian Nordic for development of...
- Press release article from: PR Newswire September 25, 2003 700+ words
...BN as a safe third-generation smallpox vaccine. The award was granted to Bavarian...appropriate milestones of Part A in the smallpox vaccine development program, and the potential...BN as a safe third-generation smallpox vaccine in Phase ll clinical studies in healthy...
- Bavarian Nordic Announces Major Accomplishments in Safe Smallpox Vaccine...
- Press release article from: PR Newswire March 7, 2005 700+ words
...major achievements in its safe smallpox vaccine program, the most recent being that its IMVAMUNE(TM) smallpox vaccine has been shown to be safer and...complications. "The ability for a smallpox vaccine to generate a fast immune response...
- Novavax Briefs Congressional Panel on Firm's Inactivated Smallpox Vaccine.
- Press release article from: PR Newswire December 6, 2001 700+ words
...organized to focus specifically on a new smallpox vaccine being developed by Novavax as a potentially...prior award of 54 million doses of smallpox vaccine, which would place enough vaccine...reflects the fact that the live virus smallpox vaccine poses significant risks. In fact...
- Bavarian Nordic Positive to Broader Usage of Safe Smallpox Vaccine.
- News wire article from: The America's Intelligence Wire August 24, 2005 700+ words
...biopharmaceutical company developing a new, safer smallpox vaccine (Imvamune(tm)), commended the...initial 20 million doses of MVA-based smallpox vaccine has begun. We have reviewed the tender...individuals, to procure MVA-based smallpox vaccine for the portion of the population...
- Govt urged to stockpile smallpox vaccine.
- News wire article from: Asia Africa Intelligence Wire July 12, 2005 700+ words
...Daily Yomiuri) Govt urged to stockpile smallpox vaccine Yomiuri Smallpox vaccine for 56 million people should be stockpiled...launch a program for creating a stockpile of smallpox vaccine on the basis of the panel's recommendations...
- Memorandum.(smallpox vaccine)
- Newspaper article from: ED Management January 1, 2003 700+ words
...House regarding the distribution of smallpox vaccine for health care workers. Current...Preparedness suggests that the initiation of smallpox vaccine on a voluntary basis will commence...following EXCLUSION criteria apply to smallpox vaccine receipt, and staff with any of these...
Source: HighBeam Research, Phase I smallpox vaccine clinical trial completed.