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2003 MAY 14 - (NewsRx.com & NewsRx.net) -- A review of DNA vaccines has been recently published in the Journal of Internal Medicine.
According to a study from France, "The DNA vaccines are simple rings of DNA containing a gene encoding an antigen, and a promoter/terminator to make the gene express in mammalian cells. They are a promising new approach for generating all types of desired immunity: cytolytic T lymphocytes (CTL), T helper cells, and antibodies, whilst being a technology that has the potential for global usage in terms of manufacturing ease, broad population administration, and safety."
"This review gives an overview of the mechanisms, preclinical and clinical efficacy of DNA vaccines, and points out the limitations of the first generation of such vaccines, and some of the promising second-generation developments," reported M. A. Liu at Transgene in ...
Source: HighBeam Research, Recent review of DNA vaccines published.