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Cancer patients experience tumor regression despite low T cell levels.

Vaccine Weekly

| May 14, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 MAY 14 - (NewsRx.com & NewsRx.net) -- Cancer patients can experience tumor regression despite low titers of antigen-specific T cells.

According to a study from Belgium, "Following vaccination with defined tumor antigens that are recognized by T cells, a small proportion of cancer patients display tumor regressions."

"Several reports describe anti-vaccine T-cell responses, evaluated with a variety of methods, for example, by assessing T-cell function or expression of specific TCR," said Pierre G. Coulie and Pierre van der Bruggen at the University of Louvain in Brussels. "However, a correlation between these T-cell responses and the tumor regressions has not yet been established."

The researchers concluded, "It appears that some patients display tumor regression with an unexpectedly low ...

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