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2003 MAY 14 - (NewsRx.com & NewsRx.net) -- The universal preadolescent vaccination program against hepatitis B appears successful in providing prenatal protection in British Columbian women.
"Countries with a low risk of hepatitis B (HB) lack data on the effectiveness of universal HB vaccination programs for children. British Columbia began a program in 1992, offering HB vaccination to 11 year olds. We conducted an anonymous, unlinked serologic survey seven years later, analyzing a random sample of specimens (n=1,215) from women aged 15-44 years who had undergone antenatal rubella testing," scientists writing in the Canadian Medical Association Journal report.
"Among those aged 15-19 years inclusive, there was no evidence of chronic HB (HB surface antigen), the proportion with evidence of acute HB (anti-HB core antibody) was only 0.6% (compared with 6.5% for the entire sample), and evidence of protective immunity was strong: the prevalence of anti-HB surface antibody (anti-HBs) was 79.1% (compared with 41.4% for the entire sample) and the geometric mean titer was 34.9 IU/mL (compared with 0.6-0.8 IU/mL for the older groups [p
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Source: HighBeam Research, Preadolescent hepatitis B vaccination program successful in Canada.