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Preadolescent hepatitis B vaccination program successful in Canada.

Vaccine Weekly

| May 14, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 MAY 14 - (NewsRx.com & NewsRx.net) -- The universal preadolescent vaccination program against hepatitis B appears successful in providing prenatal protection in British Columbian women.

"Countries with a low risk of hepatitis B (HB) lack data on the effectiveness of universal HB vaccination programs for children. British Columbia began a program in 1992, offering HB vaccination to 11 year olds. We conducted an anonymous, unlinked serologic survey seven years later, analyzing a random sample of specimens (n=1,215) from women aged 15-44 years who had undergone antenatal rubella testing," scientists writing in the Canadian Medical Association Journal report.

"Among those aged 15-19 years inclusive, there was no evidence of chronic HB (HB surface antigen), the proportion with evidence of acute HB (anti-HB core antibody) was only 0.6% (compared with 6.5% for the entire sample), and evidence of protective immunity was strong: the prevalence of anti-HB surface antibody (anti-HBs) was 79.1% (compared with 41.4% for the entire sample) and the geometric mean titer was 34.9 IU/mL (compared with 0.6-0.8 IU/mL for the older groups [p

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Source: HighBeam Research, Preadolescent hepatitis B vaccination program successful in Canada.

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