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2003 MAY 8 - (NewsRx.com & NewsRx.net) -- Some prescription medications can lower the risk of non-Hodgkin lymphoma in women.
According to recent research from the Netherlands, "earlier epidemiologic studies have suggested an inverse association between non-Hodgkin's lymphoma and exposure to histamine(2) (H-2) blockers, nonsteroidal anti-inflammatory drugs, cholesterol-lowering drugs, and antibiotics."
"Data from the PHARMO database were used to conduct a nested, population-based case-control study that included 1985-1998 drug-dispensing records for 300,000 residents of six Dutch cities," wrote A.B. Beiderbeck and coauthors at the Utrecht Institute for Pharmaceutical Science.
"Included were those subjects without a previous history of cancer who were aged more than 20 years and were registered with an incident primary discharge diagnosis of non-Hodgkin's lymphoma between 1991 and 1998," noted Beiderbeck and colleagues, whose report included "data on 211 cases and 800 controls individually matched on sex, age, community pharmacy, calendar time, and duration of follow-up."
"In multivariate analyses, nonsignificant risk reductions were found for all drugs tested, and the negative association tended to increase with ...