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The microenvironment controls ovarian capillary degeneration and angiogenesis.
2003 MAY 8 - (NewsRx.com & NewsRx.net) -- The microenvironment controls ovarian capillary degeneration and angiogenesis.
"Angiogenesis and capillary degeneration are both evident during ovarian follicle growth. However, the characteristics and distribution of thecal capillary proliferative and degenerative structures have not been fully defined. indeed, the role of thecal microvasculature changes in follicular atresia is still a matter of debate," according to published research from Japan.
"The present study examined the distribution of thecal capillary changes occurring during follicular growth and related the changes to capillary morphology (by scanning electron microscopy, SEM, on bovine ovarian corrosion casts) with the incidence of capillary apoptosis (TdT-mediated dUTP nick end-labelling, TUNEL) and follicular status (as confirmed by follicular fluid steroid concentrations)," explained J.Y. Jiang and colleagues, Tohoku University, Laboratory Animal Reproduction.
"SEM demonstrated well-perfused vascular plexuses of small to large antral follicles with structural and functional changes to capillaries. Angiogenesis was evident mainly in the apical part of the inner capillary layer of medium follicles and the middle or basal part of the inner capillary layer of dominant follicles that exhibited high oestradiol:progesterone ratios."
"Degenerative capillaries were observed mainly in the outer vascular layers of small follicles, ...
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Source: HighBeam Research, The microenvironment controls ovarian capillary degeneration and...