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Caelyx - a novel agent in the fight against metastatic breast cancer.
2003 MAY 8 - (NewsRx.com & NewsRx.net) -- Caelyx (pegylated liposomal doxorubicin hydrochloride) is a novel anthracycline that was specifically designed to address the side effects associated with conventional anthracyclines, including the risk of developing congestive heart failure, physicians reported at an investigators' forum.
Caelyx was recently approved in the European Union (EU) for the treatment of metastatic breast cancer as monotherapy in patients who are at increased cardiac risk.
An internationally recognized faculty was assembled to present the most recent scientific data on Caelyx. Pierre Fumoleau, MD, of the Centre Rene Gauducheau, Nantes-Saint Herblain, France, and Prof. Stephen R.D. Johnston, MD, PhD, of the Royal Marsden Hospital, London, served as co- chairmen of the forum. Physicians from throughout Europe attended the meeting, which was supported by Schering-Plough, marketer of Caelyx in the EU.
Jacques Bonneterre, MD, PhD, of Centre Oscar Lambret, Lille, France, presented data demonstrating an increased incidence of cardiac toxicity in patients receiving higher doses of epirubicin for the adjuvant treatment of breast cancer. Patients developing cardiac toxicity are usually not symptomatic. However, further use of conventional anthracyclines is limited since cardiac toxicity is cumulative.
Mary O'Brien, MD, of Royal Marsden Hospital, Sutton, Surrey, United Kingdom, presented data on the efficacy and relative ...
- CAELYX Demonstrates Efficacy and Reduced Cardiac Toxicity in First-Line...
- Press release article from: PR Newswire March 11, 2004 700+ words
...results with CAELYX in the treatment of metastatic breast cancer represent an...EU) for CAELYX as monotherapy...metastatic breast cancer in women who...metastatic breast cancer were randomised to receive CAELYX (50 mg/m2...
- CAELYX(R) Delays Time to Disease Progression as Maintenance Therapy in Patients...
- Press release article from: PR Newswire June 3, 2007 700+ words
...potential value of CAELYX in the management of metastatic breast cancer," said Robert...confirm that CAELYX is effective...select metastatic breast cancer patients who...approved dosage of CAELYX in metastatic breast cancer is 50 mg/m2...
- CAELYX and Herceptin Combination Shows Activity With Limited Cardiotoxicity in...
- Press release article from: PR Newswire June 5, 2004 700+ words
...treating metastatic breast cancer, combining an...important, and CAELYX is a logical choice...further evaluate the CAELYX and Herceptin combination...population. About Breast Cancer Breast cancer is...for metastatic breast cancer in patients who...cardiac ...
- CAELYX - a novel agent in the fight against metastatic breast cancer.
- Press release article from: PR Newswire April 4, 2003 700+ words
...with metastatic breast cancer, CAELYX was comparable...with CAELYX. "CAELYX provides physicians...of metastatic breast cancer, offering the...doxorubicin (CAELYX/Doxil) vs...of metastatic breast cancer [abstract...
- Caelyx - a novel agent in the fight against metastatic breast cancer.
- Newspaper article from: Cancer Weekly May 6, 2003 700+ words
...relative cardiac safety of Caelyx compared with conventional...women with metastatic breast cancer, Caelyx was comparable in efficacy...associated with Caelyx. "Caelyx provides physicians...treatment of metastatic breast cancer, offering the ability...
- Schering-Plough Announces EU Approval of CAELYX(R) in Metastatic Breast Cancer.
- Press release article from: PR Newswire January 14, 2003 700+ words
...authorization to CAELYX(R) (pegylated...for metastatic breast cancer in patients...disease. In the breast cancer clinical registration program, CAELYX was found to...treat metastatic breast cancer. Additionally, CAELYX was found to...
- Schering-Plough Reports European Union's CPMP Recommends Approval of CAELYX(R)...
- Press release article from: PR Newswire October 18, 2002 700+ words
...approval of CAELYX(R) (pegylated...for metastatic breast cancer in patients...treat metastatic breast cancer. Additionally, CAELYX was found to...with metastatic breast cancer occurring in...cases.(7) CAELYX is a long...
- Results of Caelyx study in first-line treatment of metastatic breast cancer...
- Magazine article from: Women's Health Weekly July 11, 2002 700+ words
...metastatic breast cancer. Results...demonstrated that Caelyx has an improved...results with Caelyx in the treatment...metastatic breast cancer represent...authorization for Caelyx in the European...metastatic breast cancer in women for...