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Liver fat content related to dietary fat, not body fat depots.
2003 MAY 1 - (NewsRx.com & NewsRx.net) -- The amount of liver fat was related to dietary fat, and to not body fat depots, in obese women who lost weight.
"Our objective was to determine how 8% weight loss influences subcutaneous, intra-abdominal, and liver fat (LFAT), as well as features of insulin resistance, in obese women with high versus low LFAT," scientists writing in the journal Diabetes report.
"A total of 23 women with previous gestational diabetes were divided into groups of high (9.4[+ or -]1.4%) and low (3.3[+ or -]0.4%) LFAT based on their median LFAT (5%) measured with proton spectroscopy," stated Mirja Tiikkainen and colleagues at the University of Helsinki. "Both groups were similar with respect to age, BMI, and intra-abdominal and subcutaneous fat. Before weight loss, women with high LFAT had higher fasting serum insulin and triglyceride concentrations than women with low LFAT. At baseline, LFAT correlated with the percent of fat (r=0.44, p
The researchers found, "Weight loss was similar between the groups (high LFAT -7.4[+ or -]0.2 vs low LFAT -7.7[+ or -]0.3 kg). LFAT decreased from 9.4[+ or -]1.4 to 4.8[+ or -]0.7% (p
The investigators concluded, "LFAT appears to be related to the amount of fat in the diet rather than the size of endogenous fat depots in obese women. Women with initially high LFAT lost more LFAT by similar weight loss than those with low LFAT, although both groups lost similar amounts of subcutaneous and intra-abdominal fat. These data suggest that LFAT is regulated by factors other than intra-abdominal and subcutaneous fat. Therefore, LFAT does not appear to simply reflect ...
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