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Pulmonary diffusing capacity in pregnancy is affected by residential altitude.
2003 MAY 1 - (NewsRx.com & NewsRx.net) -- The altitude where a pregnant woman spends the most time - presumably her residence - affects pulmonary diffusing capacity, study results show.
This has implications especially for pregnant women with pulmonary disease.
According to F. McAuliffe, Department Obstetrics & Gynecology at Mt. Sinai Hospital, Toronto, Canada, and colleagues there and at King's College, London, U.K., "The impact of pregnancy on respiratory function and whether this is influenced by living conditions, such as altitude of residence, must be determined if the management of pregnant women, particularly those with pulmonary disease is to be optimized."
The researchers tested their hypothesis in two groups of pregnant women living in Peru, They measured pulmonary diffusing capacity, corrected for hemoglobin concentration (DLCOc), in 112 healthy women with singleton pregnancies who lived at sea level and 19 non-pregnant controls, and 192 pregnant women living at 4300 meters and 19 non-pregnant controls.
They found that in both pregnant women and controls at sea level, mean DL(COc) levels were statistically similar, but lower than those of the group at higher altitude (both p
"At high altitude, the mean DL(COc)s of women studied ...
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