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2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Pregnant coffee-lovers can still enjoy their java in moderation, study results suggest, without worry about harmful effects of caffeine on their babies.
Since effects of mothers' caffeine intake on their fetuses was unclear, Yale University epidemiologists conducted a large prospective study, looking at data from 1996-2000 on 2,291 Connecticut and Massachusetts women with singleton births.
The women "were questioned about caffeine consumption and important confounding factors" and urine samples were analyzed for "urinary caffeine, cotinine, and creatinine levels. Mothers were followed throughout pregnancy to monitor changes in consumption. Pregnancy outcomes were obtained from medical records."
M.B. Bracken and colleagues found that intrauterine growth retardation, low birth weight, and preterm delivery were not associated with mothers' reports of how much caffeine they took in during their first and third trimesters.
"For every 1 mg/g creatinine increase in urinary caffeine, risk of intrauterine growth retardation was essentially unchanged (odds ratio (OR)=0.96, 95% confidence interval (CI): 0.85, 1.08)," reported the researchers. "In contrast, a 0.005 mg/g creatinine increase in urinary cotinine significantly increased risk (OR=1.003, 95% CI: ...
Source: HighBeam Research, Association of maternal caffeine consumption with decrements in fetal...