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Exclusive rights obtained to HIV microbicide candidate.(cyanovirin-N from Biosyn Inc. )

Women's Health Weekly

| May 01, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Biosyn, Inc., announced that the company has acquired exclusive, worldwide rights from the U.S. National Institutes of Health (NIH) for the development and commercialization of the novel protein, cyanovirin-N, as an HIV microbicide.

Cyanovirin-N (CV-N) has shown remarkably potent anti-HIV activity in laboratory studies and in animal models. Based on these data, Biosyn foresees significant potential in the development of CV-N as a microbicide to prevent the sexual transmission of HIV.

CV-N is a novel protein isolated from the cyanobacterium, Nostoc ellipsosporum (blue-green algae). Promising results of NIH research into the protein's use in preventing HIV included a primate model in which CV-N was shown to prevent transmission of simian-human immunodeficiency virus (SHIV), an HIV-like virus that infects monkeys. "CV-N is a member of an exciting new class of HIV drugs termed fusion inhibitors," stated Richard Bax, VP and chief scientific officer of Biosyn.

"By preventing HIV entry into and fusion with target cells, CV-N effectively inhibits the virus' mode of infection. As an intravaginal gel applied prior to intercourse, CV-N could help to avert the ...

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Source: HighBeam Research, Exclusive rights obtained to HIV microbicide candidate.(cyanovirin-N...

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