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Oxytocin and prostaglandins do not affect HIV replication.(Brief Article)

Women's Health Weekly

| May 01, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Oxytocin and prostaglandins (PGs) do not affect HIV replication.

These hormones are "involved in labor and are used clinically for its induction," researchers in Argentina explained.

A. Ceballos and colleagues at the University of Buenos Aires conducted a study in which "the effect of oxytocin, PGF(2alpha), and PGE(2) on human immunodeficiency virus-1 production in acutely and persistently infected cells was measured."

"No significant effect on p24 antigen production was found with oxytocin or PGs, except for a transient decrease in persistently infected cells treated with 1 microM PGF(2alpha)," they reported.

"These results showed that oxytocin and PGs could be used clinically for labor induction without any direct enhancement in viral production," Ceballos and coauthors concluded. "Besides, the results with PGF(2alpha) at the ...

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