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Women more likely to develop acute renal failure following open-heart surgery.
2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Women who undergo open-heart surgery are more likely than men to develop acute renal failure (ARF), according to research conducted at The Cleveland Clinic. ARF is strongly associated with an increased risk of mortality.
Complete results of the 7-year data appeared in the April edition of the American Journal of Kidney Diseases.
ARF is a serious complication of open-heart surgery. The study examined the influence of gender and race on the frequency of ARF in postoperative, open-heart surgery patients. More than 24,000 patients underwent open-heart surgery at The Cleveland Clinic between 1993-2000, according to the Clinic's department of cardiothoracic anesthesiology. After eliminating patients for extraordinary risk factors, a total of 22,589 patients were evaluated (30% female).
The study involved the largest absolute number of female patients (n=6738) ever reported in research examining the relationship of gender and race to ARF after open-heart surgery. In addition, the study involved one of the largest numbers of black patients (n=849, 3.7%) ever studied for the same purpose. The influence of race on the risk of ARF was not definitive, according to the research.
"This study confirms the link between ARF and postoperative mortality following open-heart surgery. Analyzing gender as an independent risk factor has allowed us to gain new insight in understanding ARF in heart surgery patients," said Charuhas ...
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