Pharmaceutical Processing articles from December 2005

Pharmaceutical Processing archives from December 2005

The more things change ...(From the Editor)
December 1, 2005... Around this time in 2004, safety questions about Vioxx were making the headlines, congressional testimony was looming and Merck's future looked grim. While no one would expect this problem to just go away--it is kind of interesting to find...

Polyethylene tank offers complete drainage.(What's Hot)
December 1, 2005... Cone bottom tank with poly-stand eliminates rust and corrosion problems. The one-piece tank is molded of durable polyethylene and is lightweight and offers less maintenance. The cone bottom design allows for complete drainage and the large...

Stainless steel AS-Interface gateways can support up to 62 addressable I/O modules in harsh environments.(What's Hot)
December 1, 2005... Available in single AS-interface or double AS-interface network versions, both gateways are ideally suited for networking safety inputs using AS-Interface Safety at Work. These modular Profibus slaves are designed in accordance with...

Linear sychronous motor module ideal for filling system.(What's Hot)
December 1, 2005... The QuickStick[TM] LSM (linear synchronous motor module) is an integrated component of Medical Instill Technologies' Intact filling system. The QuickStick enhance the fillers capacity for a variety of pharmaceutical, diagnostic, and sterile...

Packaging control system provides maximium flexibility.(What's Hot)
December 1, 2005... IndraMotion for packaging offers real-time motion control combined with an IEC 61131-3 compliant PLC, plus application-specific technology functions and PLCopen motion function blocks, scaled across three hardware platforms to provide the ideal...

Small bottle and vial filler reduces costs and eliminates repetitive strain injuries.(Process Equipment)
December 1, 2005... The FF20 offers packagers and manufacturers of clinical trial and small lot batches an automated flexible feed filling system that eliminates tedious, repetitive, pour and fill manual operations. The system works in tandem with the company's...

Liquid level monitor utilizes hall sensor technology.(Process Equipment)
December 1, 2005... Unit allows for continuous, real-time monitoring, logging and controlling of slurry/liquid level variation in a process container. Analog output boards provide the capability to control and maintain a particular target level. The remote...

Project delivery methods for pharmaceutical water systems: case studies on delivering affordable innovation.(Cover Story)
December 1, 2005... The method of design-build-validate is being used successfully to deliver pharmaceutical water systems as sub-sets of larger projects, for critical utility upgrades, and for system retrofits or enhancements. Within this model, opportunities...

Hose storage units create cleaner work environments.(Process Equipment)
December 1, 2005... Hose storage stations feature stainless steel construction and mount on a wall to create a cleaner, safer work environment and keep hose assemblies, clamps, gaskets, and adapters together and organized. Conforming to FDA and 3A regulations for...

Colloid mills reduce particle sizes uniformly.(Process Equipment)
December 1, 2005... Units feature a milling head which has a rotor and stator gap that can be adjusted while running to efficiently achieve particle size reduction and micron dispersion and emulsions of varying viscosities. Available with flow rates from 12 to...

Spiral wrap bundles, protects wiring in labs.(Process Equipment)
December 1, 2005... Heli-Tube[R] PTFE Spiral Wrap is an expandable wiring harness suitable for bundling, and protecting wires, cables and tubing in lab and harsh environments. Highly flexible for use with automated equipment or to bend around consoles and benches,...

Ball valves constructed with stainless steel.(Process Equipment)
December 1, 2005... Full-port valves are constructed with rigid corrosion-resistant Type 316 stainless steel for tank outlets, two-way in-line and three-way divert valves. The full nominal diameter ports provide slip-stream flow from inlet to outlet ports, with no...

An antidote for document overdose.(Applications)
December 1, 2005... More data was created from 2000 to 2003 than in the whole human history, according to researchers at the University of California. Unfortunately for the pharmaceutical industry, most of this data is on paper, making it difficult to locate...

Rotational vacuum concentrator suited for large sample volumes and all commonly used solvents.(Cool Technology)
December 1, 2005... Unit is designed for use in the evaporation of multiple small samples within: biology, microbiology, biochemistry, pharmaceutical research and analytical chemistry laboratories. Design features include: powerful magnetic drive system; stainless...

High retention sterilizing-grade filters provide superior protection against mycoplasma contamination.(Cool Technology)
December 1, 2005... Express[R] SHR (Sterile High-Retention) filters provide sterilizing-grade performance and mycoplasma removal across a range of applications including cell culture media and media additives, process intermediates and other biological fluids....

Pressure transmitter features stainless steel housing/measuring cell.(Cool Technology)
December 1, 2005... The Sitrans P300 pressure transmitter features a stainless steel housing and measuring cell that is flush with the front panel making it easy to clean and sterilize. The transmitter is suitable for process temperatures up to 392[degrees]F, and...

Modular chemical reactor is highly automated.(Cool Technology)
December 1, 2005... The Lara CLR is a flexible and modular chemical reactor that is both affordable and highly automated. Unit offers a choice of hardware and software components specifically designed to provide ease-of-use, time-savings, comprehensive data...

FDA and industry to collaborate on better ways to predict liver toxicity in human drug trials.(Industry News)
December 1, 2005... The FDA and BG Medicine, a Massachusetts-based biotechnology research company, have agreed to collaborate on a project designed to overcome one of the obstacles to efficient development of safe drugs. The Liver Toxicology Biomarker Study...

Feds give researchers OK for safety test of adult stem cells in patients with heart disease.(Industry News)
December 1, 2005... Researchers at Case Western Reserve University and University Hospitals of Cleveland recently announced that the FDA has approved plans to begin a study to evaluate the safety of using adult stem cells from bone marrow to treat chronic...

Sanofi-aventis Group announces new U.S. headquarters location.(Industry News)
December 1, 2005... World's Third Largest Pharmaceutical Company Plans Move To Nearby Bridgewater, NJ, Site to Accommodate Growth The Sanofi-aventis Group has signed an agreement to move its U.S. headquarters from its current location at Somerset Corporate...

Reata drug effective in preventing liver cancer.(Industry News)
December 1, 2005... Reata Pharmaceuticals, Inc. recently announced that researchers at Johns Hopkins University and Dartmouth Medical School have presented preclinical study results showing that one of Reata's synthetic triterpenoids significantly reduced the...

Metering pump offered in three configurations.(Cool Technology)
December 1, 2005... Metering pump is available in bare shaft, close-coupled and motorized configurations, each delivering smooth, metered flow free from pulsations and variations to prevent material waste or mixture imbalance. All models are capable of handling a...

Multiple grades of silicone tubing and hose meet a wide range of applications.(Cool Technology)
December 1, 2005... Company offers various grades of silicone tubing in sizes ranging from .012" through 3/4" I.D.; reinforced hose for increased pressure applications from 1/8" to 1" I.D. All manufacturing is performed in a strictly controlled, white room...

Fluoropolymer heat shrink for cryogenic applications.(Cool Technology)
December 1, 2005... Texflour Fluoropolymer Heat Shrink Tubing provides a protective covering that protects electrical wiring, conduit, or can be used in fluid transfer applications in temperatures as low as -450[degrees]F/268[degrees]C. Fluoropolymer heat shrink...

Butterfly valve offers ease-of-use and secure lock positioning.(Cool Technology)
December 1, 2005... The Pure-Fit TruValve System's design allows users to alter flow variability over standard flexible tubing or a finished assembly system, while providing tamper proof lockout positioning. Saint-Gobain Performance Plastics, Taunton, MA...

A meeting of the minds: INTERPHEX2006 conference presents information from the industry's best and brightest.(Interphex2006 Update)
December 1, 2005... In recent years, our collective knowledge of pharmaceutical development and manufacturing has expanded enormously. Yet at the same time our challenges have also multiplied, driving demand for timely, useful information that can have an...

Pressure and temperature recorder intrinsically safe.(Process Components)
December 1, 2005... The PRTEMP1000IS records both measurements independently at user-programmable reading intervals from 1 every 2 seconds to 1 every 12 hours, Featuring a stainless steel pressure strain gauge and an internal pressure sensor, it will store up to...

Pressure gauges offers increased information.(Process Components)
December 1, 2005... The Ashcroft[R] types 2032, 2132 and 2232 gauges offer features such as max/min value, alternate unit of measure or dampened value if required. Powered by battery, line or directly from a loop, gauges do the work of a pressure switch or...

Pharmaceutical catalyst recovery: how to select--and work with--the right refiner to help maximize returns and assure environmental compliance.(Applications)
December 1, 2005... Many pharmaceutical processors use a variety of precious metal-bearing catalysts for facilitating hydrogenation of various intermediates, and also for eliminating harmful exhaust emissions at end-of-pipe applications. Generally the precious...

Water Treatment System offers increased capacity in a compact package.(Cool Technology)
December 1, 2005... The MegaMagnum[R] Water Treatment System is a pre-engineered, packaged system that utilizes 18" diameter MegaMagnum membrane elements to reduce the cost, footprint and installation time of water treatment systems. A single 18" x 61" MegaMagnum...

Lab water purification system features carbon-resin technology.(Cool Technology)
December 1, 2005... The arium[R] 611 is capable of producing water with 18.2 M[omega] x cm resistivity with extremely low Total Organic Carbon (TOC) level <1 ppb, endotoxin level <0001 EU/ml and a flow rate up to 2 l/min. Depending on the application requirements...

Double Containment Piping System is easy to install.(Cool Technology)
December 1, 2005... The Poly-Flo[R] Unitary Double Containment Piping System is constructed of polypropylene and high-density polyethylene (HDPE) materials. A complete line of molded fittings for drainage or pressure applications, as well as special order...

Purification system converts tap to RO water.(Cool Technology)
December 1, 2005... The RiOs 3 water purification system is designed to meet the needs of laboratories that require up to 30 L/day of high quality pure water from tap. This adaptable system is suitable for general non-critical laboratory applications such as...

FDA increasing data mining to detect early safety signals.(Regulatory Update)
December 1, 2005... FDA is making increased use of data mining software to identify early drug safety signals in its adverse event database, Office of Pharmacoepidemiology & Statistical Science Director Paul Seligman said. The Pink Sheet reports. OPaSS has...

IND export requirements simplified in FDA final rule.(Regulatory Update)
December 1, 2005... A final rule issued by FDA simplifying requirements for investigational new drug exports prohibits transshipment of drugs from a "listed" country to an "unlisted" country where the drug does not have market authorization, but otherwise includes...

Brain tumor endpoints.(Highlights)
December 1, 2005... Brain tumor endpoints: Clinical trial endpoints for primary brain tumors will be the topic of the next public workshop in FDA's series of oncology endpoint meetings, to be held Jan. 20. "Issues identified in the workshop will be further...

Xyrem gains daytime claim.(Highlights)
December 1, 2005... Xyrem gains daytime claim: FDA cleared Jazz Pharmaceuticals' Xyrem (sodium oxybate) for treatment of excessive daytime sleepiness in patients with narcolepsy Nov. 18. Xyrem was previously approved for cataplexy in narcolepsy patients.

Emsam still in the dark.(Highlights)
December 1, 2005... Emsam still in the dark: FDA has extended the user fee date for Somerset's antidepressant patch Emsam to Feb. 26, 2006. The extension will allow FDA to review an amendment the company submitted to the NDA following the Psychopharmacologic Drugs...

Office of Women's Health director named.(Highlights)
December 1, 2005... Office of Women's Health director named: FDA names Kathleen Uhl as director of the Office of Women's Health, effective Dec. 15. Uhl has been with the Center for Drug Evaluation & Research since 1998, recently serving as the team leader for the...