Pharmaceutical Processing articles from August 2008

Pharmaceutical Processing archives from August 2008

"Lifestyle" products vs. real products.(From The Editor)
August 1, 2008... Fair warning to all readers--a long-winded and not necessarily politically correct rant is coming. Change the Channel if you wish. This is definitely not going to be rated PG and as far as I know the V-chip has no effect on print. This...

Stainless steel water cooled motors include detectors for remote monitoring.(What's Hot)
August 1, 2008... [ILLUSTRATION OMITTED] These water cooled motors are available in 5HP-500HP NEMA and IEC frames. They feature winding and bearing temperature detectors for remote condition monitoring, and stainless steel housing, water jackets and...

Valve line specifically engineered for powder handling.(What's Hot)
August 1, 2008... [ILLUSTRATION OMITTED] Range of valves and custom accessories have been developed for powder handling in the pharmaceutical, fine chemical, cosmetics and food industries. They are fully compliant with all relevant regulations and...

Hazardous chemical transfer station features glove ports for interior access.(What's Hot)
August 1, 2008... [ILLUSTRATIONS OMITTED] This apparatus for transferring hazardous material between the interior of a container and the chamber of a fume hood having a port includes a flexible enclosure with an upper surface, a lower surface and a side...

System designed for the safe transport of biopharm substances.(What's Hot)
August 1, 2008... [ILLUSTRATION OMITTED] System comprises a freeze controller and a freeze container. The control unit regulates, monitors and documents the processes for freezing and thawing the substances. In addition, it can direct the cleaning and...

Bag unloading system eliminates dust during product transfer.(What's Hot)
August 1, 2008... [ILLUSTRATION OMITTED] This sanitary bulk bag unloading system eliminates dust during untying, discharging, retying, collapse and removal of bags while allowing thorough wash down. The unloader is equipped with a patented clamp ring that...

Stainless steel bins for disposable process containers.(What's Hot)
August 1, 2008... [ILLUSTRATION OMITTED] Mobius[R] stainless steel bins provide support for handling disposable process containers filled with media, buffer, additional intermediates as well as final products. With a unique patent pending registration...

Blister printing unit offers anti-counterfeiting features.(What's Hot)
August 1, 2008... [ILLUSTRATION OMITTED] The DTS 1200 blister printing unit can be run in-line or as a stand-alone in the printing of anti-counterfeit solutions for pharmaceutical blister packs. It offers features in anti-counterfeiting and brand protection...

Trend-setting building design, multi-purpose features and equipment innovation result in award: IDT Biologika's Facility for Production of Live Human Viral Vaccines wins the 2008 Facility of the Year Award for Operational Excellence.(Cover story)(Company overview)
August 1, 2008... A combination of a trend-setting building design culminating in a multi-purpose facility, along with equipment innovation, flexibility, and effective and efficient project management resulted in IDT Biologika's Facility for Production of Live...

Use of disposables in final filling operations: converting to disposable filling components can result in significant benefits--no matter what product you are processing.(Disposables)
August 1, 2008... Single use technology continues to gain popularity in pharmaceutical and biopharmaceutical operations. One area where single use would be very beneficial is in product final filling. The following paper highlights the various benefits of...

Contamination prevention in single-use systems: Colder's John Boehm discusses important considerations for biopharm manufacturing.(Single-Use Systems)(Interview)
August 1, 2008... Single-use systems are gaining greater acceptance in biopharmaceutical manufacturing as companies increase the diversity of products they manufacture and redesign processes based on shorter, multi-product runs. Manufacturers who are...

Blister machine for high output and high speed packaging.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] The B1660 blister machine is a high performance model that is available in either continuous or intermittent motion configurations. It features a feeder allowing simultaneous tablet placement, integrated processes at...

Diaphragm metering pump with continuous gear lubrication.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] This hydraulically actuated diaphragm metering pump features a heavy-duty, continuously lubricated gear reduction system for improved pump performance and long pump life. The pumps provide accurate and leak-proof...

Laboratory high shear mixer offered for vacuum operation.(New Products)
August 1, 2008... The LCI-V model features: 1 HP variable speed drive for operation up to 10,000 rpm; 316 stainless steel wetted parts; four stator heads--slotted, square hole, fine screen and round hole; temperature probe to monitor batch temperature; vacuum...

Selection criteria for bioprocess addition vessels: key considerations for your biopharmaceutical facility.(Bioprocessing)
August 1, 2008... Addition vessels are used as components in fermentation or cell culture plants for dosing, storage, transfer or harvest of liquids. Inadequate vessels can lead to the contamination and loss of product samples and as such, deserve proper...

Fused glass cover/manway prevents particle accumulation.(Cool Technology: Aseptic Processing & Packaging)
August 1, 2008... [ILLUSTRATION OMITTED] Fused glass to metal sightglass can be used as a tank cover or manway. One piece construction offers reliability, safety and ease of opening and closing. The covers/ manways are offered with ASME or without ASME...

High efficiency mag drive pumps.(Cool Technology: Aseptic Processing & Packaging)
August 1, 2008... The DB Series premium magnetic drive pump line operates with high efficiency and has broad hydraulic coverage. High working pressure capabilities up to 90 psi allow high specific gravity fluids to be pumped safely. Maximum flow rates reach 220...

Liquid dispenser simplifies cleaning validation.(Cool Technology: Aseptic Processing & Packaging)
August 1, 2008... Liquid dispenser simplifies pharmaceutical and biotechnology cleaning validation with a new state-of-the-art peristaltic pump technology that results in significant cost savings. 100% security against product cross contamination is attained...

Laminate provides dent resistant packaging.(Cool Technology: Aseptic Processing & Packaging)
August 1, 2008... [ILLUSTRATION OMITTED] Cold Form 4000 blister laminate is ideal for light and moisture sensitive medications due to its 45 micron heavy gauge foil sandwiched between a PVC film on the sealant side and a 60 micron nylon film. It offers...

Platinum-cured tubing can withstand repeated compression.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] Class VI platinum cured tubing is a coiled tubing that has a 50A durometer and various I.D. and O.D options for biotechnical, medical and pharmaceutical applications. Platinum cured tubing provides many benefits...

Remote camera offers no image jitter.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] This compact, remote head camera features a 32.6mm x 38.6mm x 41mm frame. It includes a progressive scan system that delivers color images with no image-jitter. The camera weighs 5.74 ounces and comes equipped with...

Agitators meet wide ranging needs.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] Agitators include single motion, double motion, and sweep surface scrapers and feature many customizable options including lifting fins, brazing bars, scrapers in various materials, tilt angles, and pitched frames...

Liquid delivery accuracy advisor: solutions to your liquid handling issues: our expert answers your most pressing questions.(Instrumentation)
August 1, 2008... Some assumptions, like habits, can be unusually persistent, One common assumption is that the performance of liquid handling instrumentation--like the electronic drumbeat of a 70's disco dance tune--is dependably predictable and repeatable,...

In-line particle size measurement probe simplifies compliance.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] Two new options for the Parsum IPP-70 in-line particle size measurement probe are designed to simplify regulatory compliance for pharmaceutical applications. The Parsum IPP-70 provides real-time particle size...

Automated microbalances offer fast, precision weighing.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] The automated MX5 microbalance and UMX2 ultra microbalance are fast and precise for weighing small tubular samples. They are ideal for applications including weighing of coatings and checking thickness of tubular...

Pulse jet filters handle high loads economically.(New Products)
August 1, 2008... Pulse jet air filters are custom built for efficient, economical operation in demanding applications. Particulate-laden air is directed toward a deflector that causes heavier particles to fall directly into the collection hopper. Lighter...

Key considerations when embarking on a project to retrofit containment: as products become ever more potent, retrofitting your existing facility for containment becomes an attractive option.(Containing Contaminants)
August 1, 2008... As drug development and new chemical entities become ever more potent, we see a clear and rising trend for safety measures when these essential yet dangerous products are handled. Requirements for robust contained facilities are continually...

Dispensing pump ideal for vial or bottle filling of vaccines and diagnostics.(Cool Technology: Aseptic Processing & Packaging)
August 1, 2008... The 520Di dispensing pump is designed for accurate metering, dosing and transferring of sensitive fluids in sanitary environments. Ideal for filtration, fermentation and dispensing applications, the 520Di is well suited for filling lines in...

Semi-automatic loading and unloading system for lyophilizers.(Cool Technology: Aseptic Processing & Packaging)
August 1, 2008... [ILLUSTRATION OMITTED] System consists of a vial loading station (VLS) and a portable cart (PC) that the operator shuttles between the filling line and the lyophilizer. Features include: automatic loading of the portable cart with vials...

Powder filling line easily expanded with additional format parts.(Cool Technology: Aseptic Processing & Packaging)
August 1, 2008... [ILLUSTRATION OMITTED] This line consists of an inova brand washing machine, a SHT 1L sterilizing tunnel with sterilizable cooling zone, a filling and closing machine prepared for isolator, fully automatic loading and unloading units for...

Filling line systems offered with non-contact check weighing capability.(Cool Technology: Aseptic Processing & Packaging)
August 1, 2008... Company now offers 100% non-contact check weighing inspection equipment as part of a complete line solution. Benefits include: increased quality control and efficiency in accordance with the FDA's PAT initiative; improved process monitoring and...

Liquid enzyme cleaner for protein removal.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] This liquid enzyme cleaner removes protein-based soils in filter membrane applications and other cleaning processes. It is a blend of protease enzymes, detergents, and builders that work together to achieve broad...

Stainless steel linear systems feature self-lubricating bearings.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] These stainless steel linear systems feature self-lubricating bearing liners and are both FDA and USDA compliant. With linear travel lengths up to 136.0 inches, and shaft sizes of 0.5, 0.75, and 1.0 inches, they are...

Gearmotor mounting packages accommodate a variety of setups.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] These mounting packages include parts such as mounting brackets, 3-jaw flexible couplings, coupling guards, timing belts, pulleys, instructions and mounting hardware to accommodate a variety of setups. They are rated...

Stirred freeze drying: an examination of the process to produce loose and free-flowing powder at low temperatures and low pressures, all in one vessel.(Freeze Drying)
August 1, 2008... Discovered about one hundred years ago freeze-drying (also called lyophilization) has made a tremendous development in the previous century. From a curious lab experiment it has been evolved into a mature production technique for materials...

6 tips for establishing an effective condition based monitoring program in your facility: increase value and production with these easy-to-follow tips.(Maintenance)
August 1, 2008... Condition-based monitoring (CbM) is a maintenance process where the condition or health of plant equipment is monitored for the earliest signs of impending failure. An effective CbM program does not have to be extremely complicated nor...

PVC films designed for blister packaging.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] These PVdC coated PVC films are manufactured to offer users high clarity PVdC coatings available at 40 grams per square meter and up in both duplex and triplex constructions. The films meet all regulatory...

Mixer ideal for large volumes.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] This magnetically coupled mixer offers effective mixing in large volumes as high as 30,000 liters. Its aseptic design makes it ideal for use in mixing operations in sterile production of pharmaceuticals while the...

Self-repairing door ideal for use in interior openings.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] This high speed roll-up door is ideal for use on interior openings up to 14' x 16' and has an opening speed of up to 100" per second which promotes effective material handling and contributes to energy savings. In...

Cleanroom cabinet oven used for depyrogenation of glassware.(Cool Technology: Clean Rooms)
August 1, 2008... [ILLUSTRATION OMITTED] The No. 962 is a 500[degrees]F (257[degrees]C) electrically-heated, Class 100 cleanroom cabinet oven currently used for pass-through depyrogenation of glassware. Workspace dimensions measure 24"W x 36"D x27"H. 10KW...

Cleanroom pass-throughs offer simplified cleaning and sterilizing.(Cool Technology: Clean Rooms)
August 1, 2008... BioSafe[TM] Pass-Throughs incorporate coved corners and ultra-smooth 304/316 stainless steel surfaces to simplify cleaning and sterilization in critical aseptic applications. No-lip edges eliminate clearance obstructions for easy material...

Circular chart recorder features microprocessor control.(Cool Technology: Clean Rooms)
August 1, 2008... [ILLUSTRATION OMITTED] The microprocessor-based CT6100 Series circular chart recorders combine the simplicity and clarity of pen drawing with the versatility of microprocessor control while providing a high level of accuracy and stability....

Vibration isolation workstation is designed specifically for use in cleanrooms.(Cool Technology: Clean Rooms)
August 1, 2008... [ILLUSTRATION OMITTED] The 9600 Series is constructed of stainless steel using cylindrical welded braces for maximum rigidity, minimum flat surfaces, and easy wipedown. An enclosed isolation module, stainless steel valves, and vented...

Thermoplastic valve boxes offer protection in harsh environments.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] These customized valve boxes provide easy, convenient protection for all valves and valve assemblies. Available in PolyPro, HDPE, PVDF, ECTFE (Halar), PVC, or CPVC, these fully enclosed boxes offer protection against...

Multipurpose PVC tubing available in over 50 sizes.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] Ranging from 1/16" through 4" ID., these tubes meet the requirements of a wide variety of industries including pharmaceutical, food, medical, and chemical. It handles an assortment of applications involving liquid...

Flexible silos provide custom solutions for bulk solids storage.(New Products)
August 1, 2008... This range of flexible silos provides tailor-made solutions for quick, efficient and safe storing of bulk solids and ingredients in most industries. They are made of a durable and flexible polyester fabric supported on a steel frame. The silos...

Machine, heal thyself: improving packaging machine productivity with drive-based predictive maintenance.(Packaging)
August 1, 2008... Human protective reflexes are triggered by the central nervous system, bypassing conscious thought and operating with extraordinary speed. This distributed "nervous system" concept can be transferred to automation: integrating diagnostics and...

Wireless data acquisition system provides analog and contact inputs.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] The DR9011 wireless transmitter provides analog and contact closure data transmission to a companion DR9021 where the data is recovered. The analog data is recovered as two 4-20mA outputs and the switch data is...

Nanofiltration elements ideal for desalting and separating antibiotics.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] Ideally suited for desalting and the separation of antibiotics and APIs, the SPIRAPRO TFC elements utilize a proprietary, polyamide thin-film composite membrane with a sanitary spiral-wound net outerwrap. The...

Particle analyzers deliver zeta potential and submicron size measurement.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] The Delsa[TM] Nano Series Particle Analyzer performs zeta potential and particle size analysis on the same sample. The systems are designed to deliver accurate size measurement on particles ranging from 0.6 nm to 7...

Levitated impeller mixing system ideal for biopharm applications.(Cool Technology: Disposables)
August 1, 2008... [ILLUSTRATION OMITTED] The Flexel[R] 3D LevMix System for Palletank[R] is a single-use mixing solution using a LevTech levitated impeller and a Sartorius Stedim Biotech Flexel 3D bag combined with the cubical mixing tank based on Palletank...

Aseptic bag filler eliminates cross contamination.(Cool Technology: Disposables)
August 1, 2008... [ILLUSTRATION OMITTED] The AFL1000 aseptic bag filler is a sterile single use disposable fill line. Features and benefits include: eliminates possibility of cross contamination; disposable filter part of the fill line; eliminates CIP/SIP...

Clamp eliminates distortion in non-metallic sanitary flanges.(Cool Technology: Disposables)
August 1, 2008... [ILLUSTRATION OMITTED] The Bio Clamp[TM] is constructed of a glass reinforced nylon resin and does not promote distortion in non-metallic sanitary flanges as do stainless steel clamps. Due to its light weight they do not stress connection...

Disposable mixing system minimizes particle generation.(Cool Technology: Disposables)
August 1, 2008... The Mobius MIX500 disposable mixer features a configurable 500-liter container. The instant-on, levitating magnetically-driven impeller minimizes particle generation and enables risk-free media and buffer preparation. As a part of an integrated...

Precise barcode scanning in ultra-compact package.(New Products)
August 1, 2008... With a footprint of 22 mm x 30 mm x 40 mm, this small scanner delivers 0.15mm (6 mil) resolution to read very small labels, and operates at a speed up to 1200 scan/s. It is ideal for applications where space is limited and demands are high....

Capsule filler ideal for R&D to full production.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] This continuous motion capsule filler features an output of up to 100,000 capsules per hour, and has a modular design that allows for different dosing units to be fitted at the same time, permitting filling of...

1/16 DIN ramp, soak temperature, process controllers.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] The front panel of the CN6201 features a dual display and has a splash proof and dust-proof design. The universal input supports thermocouple, RTD and voltage input types. Units offer I program pattern consisting of...

Portable agitators offer a variety of mixing options.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] These agitators provide a variety of mixing options and can handle a wide range of products. Triple motion agitators feature three independent motors and may also be provided with vacuum and pressure capabilities....

Digital handheld calibrator for pressure/temperature measurement.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] Handheld precision calibrator offers practical features designed to meet modern line-test application requirements. With a modular sensor system, the PTE-1 can be configured to measure ranges from 0-.25" H20 to...

Programmable dispensing system uses precision stepper motors.(New Products)
August 1, 2008... [ILLUSTRATION OMITTED] Programmable dispensing system uses precision stepper motors to control a variety of valveless piston pumps now has a range from 500 nanoliters per dispense to 2 liters per minute continuous flow. It accommodates all...

FDA revises process for responding to drug applications.(FDA Update: A monthly compendium of news features, announcements, regulatory issues and approvals from the Food & Drug Administration.)
August 1, 2008... The FDA is revising the way it communicates to drug companies when a marketing application cannot be approved as submitted. Under new regulations that govern the drug approval process, FDA's Center for Drug Evaluation and Research (CDER)...

HHS announces international programs to enhance drug and food safety.(FDA Update: A monthly compendium of news features, announcements, regulatory issues and approvals from the Food & Drug Administration.)
August 1, 2008... U.S. Health and Human Services (HHS) Secretary Mike Leavitt recently announced two groundbreaking programs designed to enhance the safety of food and medical products exported to the United States. "These programs will significantly...

FDA grants Samaritan's HIV drug IND status.(FDA: RECENT APPROVALS)(Clinical report)
August 1, 2008... * Samaritan Pharmaceuticals has filed an IND (Investigational New Drug) application for SP-6310 in the treatment of HIV infected patients with abnormal cortisol levels. Following, discussions and protocol agreement with the FDA. Samaritan will...