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Robotic surgery on the cutting edge.(Gynecologic Surgery)
May 1, 2006... PHOENIX, ARIZ. -- It may seem unfathomable to them now, but there was a time when the surgeons at the Mayo Clinic Hospital mulled the possibility that an operating room robot might wind up in a corner, collecting dust.
"It is not an...
Top 10 reasons for ob.gyn. visits in 2005.(VITAL SIGNS)(Table)
May 1, 2006...
Top 10 Reasons for Ob.Gyn. Visits in 2005
Supervision of normal 2nd or later pregnancy 16.6%
Gynecologic exam 13.6%
Contraceptive counseling 5.7%
Symptomatic menopausal state ...
Nitroglycerin patch improves preterm neonatal outcomes: results seen despite no delay in delivery.(NEWS)
May 1, 2006... TORONTO -- Transdermal nitroglycerin improved neonatal outcomes but didn't significantly delay time to delivery, according to results of the Canadian Preterm Labor Nitroglycerin Trial.
"Given that there is no standard of care [for the...
Early oophorectomy may predict cognitive decline.(NEWS)
May 1, 2006... SAN DIEGO -- Women who underwent oophorectomy had an increased risk for developing dementia and cognitive impairment, especially if the surgery occurred before age 38, preliminary results from a large historical cohort study demonstrated.
...
Four criteria may confirm ovarian ca.(NEWS)
May 1, 2006... PALM SPRINGS, CALIF. -- The best predictor for ovarian malignancy in a postmenopausal woman with an initial abnormal screen is a CA 125 level greater than or equal to 65 U/mL, Dr. Edward E. Partridge said at the annual meeting of the Society of...
CMS proposes 4.6% physician pay cut for 2007.(NEWS)
May 1, 2006... In a not unexpected, but definitely unwelcome move, the Centers for Medicare and Medicaid Services has announced that it will cut physician pay by 4.6% for 2007.
The federal health program said the scheduled decrease in physician fees is...
List of certified EHRs expected by midsummer: electronic health record products will be evaluated based on more than 250 functional requirements.(NEWS)
May 1, 2006... PHILADELPHIA -- Physicians purchasing an electronic health record will be able to consult a list of certified products as early as this summer, according to Dr. Mark Leavitt, chair of the Certification Commission for Healthcare Information...
Four lots of cefazolin for injection recalled for microbial contamination.(NEWS)
May 1, 2006... Hanford Pharmaceuticals Inc. has recalled four lots of cefazolin for injection due to the possibility of microbial contamination, which may pose a serious or life-threatening risk for some patients.
The recall affects 379,975 vials (1 g/10...
More studies back patient-initiated herpes therapy.(NEWS)
May 1, 2006... SAN FRANCISCO -- A single, patient-initiated dose of famciclovir cut short recurrent outbreaks of herpes labialis by 2 days, Dr. Marcus Conant said at the annual meeting of the American Academy of Dermatology.
Viral replication of the...
Surgical care for ovarian ca not what it should be.(News)
May 1, 2006... PALM SPRINGS, CALIF. -- A significant number of women in the United States are not receiving the recommended surgical procedures for ovarian cancer, results from an analysis of hospital discharge data suggest.
"Approximately 50% of women...
Why give the WHI diet study credence?(GUEST EDITORIAL)
May 1, 2006... Counseling and motivating our patients to change their diet and lifestyle are tough enough, but the results from the Women's Health Initiative's examination of low-fat diets are likely to make that job even harder.
The study results, which...
Routine herpes screening in pregnancy pays off.(GUEST EDITORIAL)
May 1, 2006... It is cost effective and good clinical care to screen all pregnant women with a type-specific antibody test for herpes.
Although the American College of Obstetricians and Gynecologists does not currently recommend it, I have found that...
Be skeptical of drug industry defenders.(LETTERS)(Letter to the editor)
May 1, 2006... The relationship between physicians and the pharmaceutical industry is important and needs further consideration ("Defending the Drug Man," Guest Editorial, Jan. 15, 2006, p. 9).
The issue is important because of its effect on the ethical...
C-section increases later risk of placenta previa.(Obstetrics)
May 1, 2006... TORONTO -- Women whose first babies are delivered by cesarean section face an elevated risk of placenta previa and placental abruption in their second pregnancies. And with two previous cesarean deliveries the risk of placenta previa is...
Ultrasound's value as placental screen affirmed.(Obstetrics)
May 1, 2006... MIAMI BEACH -- Pelvic ultrasound is accurate for ruling out placenta accreta, and should be used as the primary screening tool in patients at high risk for this condition, Dr. Carri Warshak said at the annual meeting of the Society for...
Pregnant smokers: Tobacco road can be hard to exit.(Obstetrics)
May 1, 2006... ORLANDO -- Pregnant women who are not heavy smokers may be more likely to successfully quit, according to research presented at the annual meeting of the Society for Research on Nicotine and Tobacco.
Lower amounts of smoking, adequate...
Lone umbilical artery indicates need for fetal ECG.(Obstetrics)(echocardiography)(Brief article)
May 1, 2006... MIAMI BEACH -- A prenatal sonographic finding of single umbilical artery is an indication for fetal echocardiography, Dr. Lami Yeo said at the annual meeting of the Society for Maternal-Fetal Medicine.
In a case series of 430 fetuses with...
Thrombophilia not at fault in fetal losses.(Obstetrics)
May 1, 2006... TORONTO -- Recurrent pregnancy loss was not associated with inherited maternal thrombophilias in a prospective study, adding weight to the evidence against screening for such disorders in patients presenting with a history of first-trimester...
Nifedipine faster, safer than magnesium sulfate.(Obstetrics)
May 1, 2006... MIAMI BEACH -- Oral nifedipine is a faster acting and safer tocolytic than magnesium sulfate is, findings of a recent randomized study suggest.
A total of 192 women who presented between 24 and 34 weeks' gestation with contractions and...
Lupus treatment advised despite pregnancy concern.(Obstetrics)
May 1, 2006... SNOWMASS, COLO. -- Lupus treatment should not be discontinued in anticipation of a pregnancy, Dr. W Joseph McCune said at a symposium sponsored by the American College of Rheumatology.
Terminating drug treatment results in flares, and it is...
Success rates similar for preterm, term VBAC.(Obstetrics)(vaginal birth after cesarean)
May 1, 2006... MIAMI BEACH -- A trial of labor should be considered an option for women with a history of prior cesarean delivery when preterm delivery is anticipated, Dr. Celeste P. Durnwald said at the annual meeting of the Society for Maternal-Fetal...
Preconception dieting raises preterm risk.(Obstetrics)
May 1, 2006... TORONTO -- Women who diet to lose weight before getting pregnant could be at increased risk of giving birth prematurely, according to Jim Johnstone of the department of physiology at the University of Toronto.
The findings, which he...
Biology, behavior raise STD risks for adolescents.(Gynecology)
May 1, 2006... NEW YORK -- Adolescents are disproportionately affected by sexually transmitted diseases because of biologic, psychological, cognitive, and behavioral factors, as well as poor access to health care, Dr. Robin Recant said at a gynecology...
One-third of U.S. girls sexually active by age 15.(Gynecology)
May 1, 2006... BOSTON -- By age 15, more than a third of American girls say they are sexually active, according to a Centers for Disease Control and Prevention survey. About 26% have had oral sex, 26% have had vaginal intercourse, and another 8% have had oral...
Managing adolescent breast masses.(Gynecology)
May 1, 2006... NEW YORK -- When evaluating a breast mass in an adolescent, keep in mind that breast cancer is rare in this population and imaging should be limited, Dr. Patricia Simmons advised physicians at a gynecology conference sponsored by Mount Sinai...
Young black women at risk for aggressive breast tumors.(Gynecology)
May 1, 2006... WASHINGTON -- Aggressive breast tumors, known as "triple negatives," are significantly more common among black women--especially younger women--than in white women, reported Mary Jo B. Lund, Ph.D., at the annual meeting of the American...
DMPA at initial visit cuts unintended pregnancies.(Gynecology)
May 1, 2006... BOSTON -- The immediate initiation of depot medroxyprogesterone acetate to adolescent and young adult women seeking the contraceptive injection resulted in higher continuation rates and substantially diminished unintended pregnancy rates at 6...
Some women may be allergic to hormones.(Gynecology)
May 1, 2006... The hormones progesterone and estrogen might provoke allergic antibody reactions in some women, which might in turn help explain various menstrual disorders, according to a prospective study.
Dr. Russell R. Roby and colleagues from the Roby...
HPV screening in teens not cost effective.(Gynecology)
May 1, 2006... NEW YORK -- Screening for the human papillomavirus in adolescent females is not cost effective because of the high rate of infection in that population, Dr. Edyta C. Pirog said at a gynecology conference sponsored by Mount Sinai School of...
Genital Gram stains unreliable as STI detectors.(Gynecology)
May 1, 2006... WASHINGTON -- Genital Gram stains alone lack the diagnostic ability to detect Chlamydia trachomatis and Neisseria gonorrhoeae infections, based on data from 1,511 emergency department visits, reported Dr. Shanda Riley in a poster at the annual...
Self-testing for HPV preferred by majority in study.(Gynecology)
May 1, 2006... PALM SPRINGS, CALIF. -- Women who do not participate in routine screening programs may prefer self-testing for human papillomavirus with a tampon or cotton swab over testing administered by a physician, Dr. Robert P. Edwards reported in a...
Menopausal hormones may bring on depression.(Gynecology)
May 1, 2006... The "changing hormonal milieu" of menopause is strongly associated with new-onset major depression as well as depressive symptoms in women with no history of mood disturbance, reported Ellen W. Freeman, Ph.D., of the departments of ob.gyn. and...
Fracture risk linked to pelvic organ prolapse: collagen deficiencies may explain the presence of prolapse, bone fragility in postmenopausal women.(Gynecology)
May 1, 2006... TORONTO -- Women with pelvic organ prolapse may be at more risk for fracture, according to a new analysis of data from the Women's Health Initiative trial.
"As a clinician, if I see a woman who is early postmenopausal with moderate to...
Depression risk nearly doubles when women enter menopause.(Gynecology)
May 1, 2006... Women entering menopause are nearly twice as likely to develop depression as are women the same age who are not yet making the transition to menopause, reported Dr. Lee S. Cohen and his associates in the Harvard Study of Moods and Cycles.
...
New device described as objective test of pelvic floor musculature.(Gynecology)
May 1, 2006... FORT LAUDERDALE, FLA. -- The Colpexin sphere, an intravaginal device for women with advanced genital prolapse that supports the prolapse above the levator musculature and helps patients strengthen their pelvic floor muscles, can also serve as a...
Submucous uterine fibroids.(MASTER CLASS)
May 1, 2006... Uterine fibroids are the most common benign tumor of the female genital tract. Almost 40% of the 600,000 hysterectomies performed each year in the United States are performed for symptomatic fibroids. Given the fact that many fibroids occur in...
Hysteroscopic myomectomy safe and easy.(Gynecologic Surgery)
May 1, 2006... Contrary to what many still believe, hysteroscopic myomectomy can be one of the safest, mostly easily learned surgical procedures in gynecology. It is certainly underutilized and continues to be offered and performed by relatively few...
If fertility is a consideration, choose myomectomy over UFE.(Gynecologic Surgery)(uterine fibroid embolization)
May 1, 2006... TORONTO -- Fibroid patients who want to preserve or improve their chances of having children should undergo uterine fibroid embolization only if they are not good candidates for myomectomy, Dr. Gary P. Siskin told his colleagues at the annual...
When to try surgical treatment for tubal disease.(Gynecologic Surgery)
May 1, 2006... PASADENA, CALIF. -- The conundrum of whether tubal disease should be treated before moving on to assisted reproductive technologies has persisted for nearly three decades--since in vitro fertilization was first developed to compensate for tubal...
Questionnaire increases use of preop protocols.(Gynecologic Surgery)
May 1, 2006... WASHINGTON -- Use of a questionnaire prior to surgery can greatly increase compliance with preoperative protocols, Anika Backster and her associates wrote in a poster at a meeting sponsored by the National Hispanic Medical Association.
...
Laparoscopy gets qualified nod in uterine cancer.(Gynecologic Surgery)
May 1, 2006... PALM SPRINGS, CALIF. -- Laparoscopic surgical staging of uterine cancer is feasible for most patients with clinical stage I-IIA uterine cancer, Dr. Joan L. Walker reported at the annual meeting of the Society of Gynecologic Oncologists.
...
Fondaparinux plus compression prevents VTE.(Gynecologic Surgery)
May 1, 2006... PALM SPRINGS, CALIF. -- Once-daily fondaparinux 2.5 mg for 5-7 days combined with pneumatic compression was significantly more effective than intermittent pneumatic compression alone for preventing venous thrombosis after elective major...
Mean robotic hysterectomy time 129 minutes, few complications.(Gynecologic Surgery)
May 1, 2006... TUCSON, ARIZ. -- A retrospective study of 91 robotic hysterectomies performed at the Mayo Clinic Hospital in Phoenix determined that the new approach results in "acceptable operating times and surgical outcomes."
Dr. Rosanne Kho reported...
Checking in after day surgery averts lawsuits.(Gynecologic Surgery)
May 1, 2006... PASADENA, CALIF. -- Short-stay surgery has many practical and financial advantages, but it deprives the physician of making rounds in the hours and days following surgery--a fertile time for complications and, quite possibly, seeds of a...
Complication rates similar with Sutures and drains for high BMI.(Gynecologic Surgery)
May 1, 2006... ORLANDO -- Sutures and drains are associated with equal rates of wound complications when used in the subcutaneous management of vertical incisions in women with more than 3 cm of subcutaneous fat after abdominal wall closure of vertical...
Radiation can be reduced in uterine fibroid embolization.(Gynecologic Surgery)
May 1, 2006... NICE, FRANCE -- German investigators significantly reduced radiation exposures without causing complications in 64 women undergoing uterine fibroid embolization.
Bilateral embolization was possible in 63 patients, Dierk Vorwerk, M.D.,...
Preoperative OCs smooth the way for hysteroscopic sterilization with Essure.(Gynecologic Surgery)
May 1, 2006... CHICAGO -- A short course of oral contraceptives prior to hysteroscopic sterilization can make it easier to place the device, Dr. Sarit Aschkenazi-Steinberg reported in a poster at the annual meeting of the AAGL (formerly the American...
Three studies highlight hypertension treatments: a hormone therapy, a reformulated [beta]-blocker, and the benefits of lowering BP and lipids are reviewed.(Clinical Rounds)
May 1, 2006... ATLANTA -- A new hormone therapy for postmenopausal symptoms also has a significant antihypertensive effect; the popular [beta]-blocker carvedilol comes in a once-daily formulation; and an analysis of more than 600 patients with hypertension...
Multiple lifestyle changes are sustainable, can control BP.(Clinical Rounds)
May 1, 2006... People with prehypertension and hypertension can make and sustain multiple lifestyle modifications, controlling their blood pressure and perhaps reducing their risk for many chronic diseases, according to Patricia J. Elmer, Ph.D., of Kaiser...
Report equates PPIs, surgery as GERD treatments.(Clinical Rounds)
May 1, 2006... Proton pump inhibitors are as effective as surgery for the treatment of most patients with uncomplicated gastroesophageal reflux disease, according to a new report from the Agency for Healthcare Research and Quality, Rockville, Md.
The...
Cancer surgery survival better at busy hospitals: two strategies--selective referral and quality improvement--might address the disparities.(Clinical Rounds)
May 1, 2006... SAN DIEGO -- A new study has found that foregut cancer patients are significantly more likely to live 5 years after surgery if their operations are performed in hospitals doing a large number of procedures annually, Dr. John D. Birkmeyer said...
Hospitals urged to improve monitoring of pain medications.(Clinical Rounds)
May 1, 2006... LOUISVILLE, KY. -- Overmedication of pain with narcotics and sedatives may be a growing problem in hospitals and should be monitored with the same regularity as pain, Dr. Charles E. Lucas said at the annual meeting of the Central Surgical...
Rape linked with acute inflammatory changes.(Clinical Rounds)
May 1, 2006... SAN FRANCISCO -- Rape appears to initiate a host of neuroinflammatory changes that could predispose the victim to later inflammatory disease, Maureen Groer, Ph.D., said at the annual meeting of the Society of Behavioral Medicine.
"Victims...
Illness, abuse are associated with chronic pelvic pain.(Clinical Rounds)
May 1, 2006... Pelvic disease, psychological morbidity, and a history of abuse are the factors most strongly associated with chronic pelvic pain in women, according to a metaanalysis including data on more than 90,000 patients.
Dr. Pallavi Latthe and...
MRSA hits neonatal units; hand hygiene cited.(Clinical Rounds)
May 1, 2006... Outbreaks of community-associated methicillin-resistant Staphylococcus aureus among healthy, term newborns in Chicago and Los Angeles County hospitals probably originated in the newborn nursery and illustrate the critical importance of...
Oracea called best nonantibiotic Tx for rosacea: the once-daily, 40-mg, controlled-release dose falls below doxycycline's threshold of antibiotic activity.(Clinical Rounds)
May 1, 2006... KOLOA, HAWAII -- With marketing approval of the anti-inflammatory, nonantibiotic formulation of doxycycline for treatment of rosacea widely anticipated by the end of this month, this new once-daily oral agent is likely to be viewed as the best...
Alternative cancer therapies are heading for more clinical studies.(Clinical Rounds)
May 1, 2006... LA JOLLA, CALIF. -- An emerging trend in complementary and alternative medicine is a shift away from animal-only studies and toward clinical trials involving the use of herbs for cancer treatment, Dr. Mary L. Hardy said at a meeting on natural...
Fusarium-linked contact lens solution pulled.(Clinical Rounds)
May 1, 2006... Federal, state, and local health officials are investigating at least 109 cases of Fusarium keratitis in which the use of a contact lens solution may have played a role.
Bausch & Lomb, which had stopped shipment of the product, ReNu with...
Female pattern hair loss may need more finasteride.(Clinical Rounds)
May 1, 2006... Finasteride, taken at a higher dosage than is approved for male androge-netic alopecia, improved female pattern hair loss in 23 of 37 premenopausal women who used it for 1 year, reported Dr. Matilde Iorizzo and her associates at the University...
Informed consent requirements.(POLICY & PRACTICE)
May 1, 2006... The Florida Supreme Court recently upheld as constitutional the state's requirement that physicians provide certain information to women before an abortion. But the court decision also held that while informed consent could be required,...
Breast cancer survival.(POLICY & PRACTICE)
May 1, 2006... Women who are socially isolated are more likely to die from breast cancer, according to a study published in the Journal of Clinical Oncology. Researchers found that women without close relatives or friends had a 66% higher risk of dying from...
Pregnancy prevention.(POLICY & PRACTICE)
May 1, 2006... A group of House Republicans recently asked the Government Accountability Office to review the curricula of 24 federally funded teen pregnancy prevention programs for accuracy and age-appropriate content. "We are requesting an investigation...
AIDS Drug Assistance.(POLICY & PRACTICE)
May 1, 2006... Waiting lists and cost-containment measures continue to be a fact of life at the state and territorial AIDS Drug Assistance Programs (ADAPs) that serve as the primary drug safety net for individuals with HIV/AIDS, according to the National ADAP...
Mifepristone review.(POLICY & PRACTICE)
May 1, 2006... Members of the House Pro-Life Caucus have urged the Food and Drug Administration to withdraw the abortifacient mifepristone from the market, pointing to reports of deaths of women who have taken the drug. The FDA is currently investigating...
Two heavy smokers and how they quit.(THE REST OF YOUR LIFE)
May 1, 2006... The day Dr. Robert L. Kistner turned his back on cigarette smoking, a behavior he began as a 14-year-old growing up in St. Louis, was Jan. 1, 1982.
"I smoked through high school, college, and through medical school and the Air Force," said...
Medical board probes: first of all--call a lawyer.(Practice Trends)
May 1, 2006... PASADENA, CALIF. -- Your state medical board requests medical and billing records from your office.
You are advised to appear for an interview with state medical board representatives.
Investigators from the state medical board show up...
New law puts pseudoephedrine behind counter.(Practice Trends)
May 1, 2006... Over-the-counter drugs containing pseudoephedrine will go behind the counter beginning in late September under a new law passed by Congress and signed by President Bush.
The Combat Methamphetamine Epidemic Act of 2005--passed as part of...
Survey dispels worries of genetic bias by insurers.(Practice Trends)
May 1, 2006... SAN ANTONIO -- The specter of discrimination based on genetic test results has turned out to be greatly overblown, Dr. Kenneth Offit said at a breast cancer symposium sponsored by the Cancer Therapy and Research Center.
"It's a topic we've...
Self-care, support may lower physician stress.(Practice Trends)
May 1, 2006... TUCSON, ARIZ. -- Medicine is a high-risk profession for psychiatric morbidities. But several strategies can help reduce the risk of hitting bottom, Dan Shapiro, Ph.D., said at a psychopharmacology conference sponsored by the University of...
Waterproof medical keyboard.(PRODUCTS)
May 1, 2006... The "Really Cool" keyboard is waterproof and can be cleaned with water, soap, alcohol and other disinfectants to promote infection control. The keyboard retails for $169 and is USB and PS/2 compatible. For more information, contact Man &...
Prenatal vitamins include DHA.(PRODUCTS)
May 1, 2006... The Citracal Prenatal + DHA prenatal pack contains a daily dose of prescription-strength vitamins and minerals and a 250-mg capsule of Martek DHA omega-3 fatty acid. Docosahexaenoic acid supplementation is an alternative to eating fish during...
Disposable germicidal wipes.(PRODUCTS)
May 1, 2006... Super Sani-Cloth and Sani-Cloth Plus wipes are designed for use on hard, non-porous surfaces such as carts, counters, exam tables, and monitoring equipment. For more information, contact Professional Disposables International by visiting...
Cervical Imaging System available.(PRODUCTS)
May 1, 2006... The Luma Cervical Imaging System is an FDA-approved optical imaging device for examining women with abnormal Pap tests and is designed to be used as an adjunct to colposcopy. For more information, contact MediSpectra Inc. by visiting...
Web site offers handy mnemonics.(FYI)
May 1, 2006... The Medical Mnemonics Web site offers a free, online, searchable database of medical mnemonics to help remember important details. The database is also available for PalmOS, PDF, AvantGo, and WAP, and is customizable. For more information,...
Trichomoniasis booklet is offered.(FYI)
May 1, 2006... The booklet "Trichomoniasis: The Most Common Curable STD" describes the key aspects of this common cause of vaginal infections. The booklet is available free of charge from Presutti Laboratories by calling 888-405-7800 or by sending an e-mail...
National breast Milk Bank.(FYI)
May 1, 2006... The National Milk Bank collects donated human milk, ensures milk safety and quality, and makes it available for premature and critically ill infants. For more information, visit www.nationalmilkbank.org or call 866-522-6455.
Research targets evolution of CIN.(News)
May 15, 2006... LAS VEGAS -- Chemopreventive therapeutic agents may be able to alter the molecular changes that occur in the progression from preinvasive to invasive cervical disease, Dr. Janet S. Rader said at a meeting of the American Society for Colposcopy...
Percentage of IMGs in Ob.Gyn. steady over time.(VITAL SIGNS)
May 15, 2006... Percentage of IMGs in Ob.Gyn. Steady Over Time
Source: American Medical Association
ELSEVIER GLOBAL MEDICAL NEWS
Combo HT curbs hot flashes, cuts blood pressure: drospirenone has antialdosterone effects.(News)
May 15, 2006... WASHINGTON -- The combination of drospirenone (a progestin with antialdosterone effects) and 17-[beta]-estradiol as hormone therapy for hypertensive postmenopausal women not only reduces their hot flashes, but lowers their blood pressure as...
Previous early c-section ups future rupture risk.(News)
May 15, 2006... MIAMI BEACH -- Women with a history of preterm cesarean delivery are twice as likely to experience uterine rupture during a subsequent vaginal delivery, compared with women who have a history of operative delivery at term, according to a large...
Raloxifene matches tamoxifen for breast cancer: the star trial measured prevention of invasive breast cancer in women at high risk for the disease.(News)
May 15, 2006... Raloxifene is as effective as tamoxifen in preventing invasive breast cancer in postmenopausal women, according to initial results of the Study of Tamoxifen and Raloxifene (STAR) trial.
The large, randomized, double-blind trial also...
Pregnancy complications may mark increased risk for premature CAD.(News)
May 15, 2006... ATLANTA -- Consider pregnancy complications to be a red flag for premature coronary artery disease, Dr. Mimi S. Biswas said at the annual meeting of the American College of Cardiology.
She presented a retrospective cohort study involving...
Delaying conception urged after cervical conization.(News)(Brief article)
May 15, 2006... TORONTO -- Women who undergo cervical conization for the treatment of cervical intraepithelial neoplasia may benefit from delaying conception for about a year to reduce their risk of preterm birth, Dr. Katherine P. Himes said at the annual...
Thalidomide aids topotecan efficacy in ovarian ca.(News)
May 15, 2006... PALM SPRINGS, CALIF. -- Combining thalidomide with topotecan for the treatment of recurrent ovarian cancer significantly increased the response to therapy and the duration of progression-free survival without added toxicity, according to a...