Journal of Drugs in Dermatology articles from May 2005

Journal of Drugs in Dermatology archives from May 2005

A letter from the Editor-in-Chief.
May 1, 2005... The demand for knowledge in dermatology from professionals outside of our field has been increasing exponentially. Unfortunately, dermatology is not a required subject in many medical schools. Even in residency other specialties have limited...

In contrast with PAR-2 mediated nociception and hyperalgesia, melanosome transfer does not involve N-methyl-D-aspartate receptors.(LETTERS TO THE EDITOR)(Letter to the Editor)
May 1, 2005... The mechanism of melanosome transfer from melanocytes to keratinocytes is believed to be a type of cytophagocytosis, regulated by a keratinocyte receptor called protease-activated receptor-2 (PAR-2). (1) PAR-2, expressed in keratinocytes but...

Mechanism-based treatment of acne vulgaris: the value of combination therapy.
May 1, 2005... Abstract Acne vulgaris has multiple pathogenic mechanisms that act in concert to produce disease. Effective therapy addresses more than one pathogenic factor to speed resolution of disease. Typically, retinoids are used to inhibit comedo...

A chart review of patients with early stage mycosis fungoides treated with psoralen plus UVA (PUVA).
May 1, 2005... Abstract PUVA has become a common form of treatment for early stage mycosis fungoides (MF). The purpose of this retrospective study was to review the clinical data of 51 MF patients (96% stage IA or IB) treated with PUVA at the Mt. Sinai...

Therapeutic decision making in the therapy of actinic keratoses.
May 1, 2005... Abstract Actinic keratoses (AKs) represent the second most common reason to visit a dermatologist in the United States and their therapy has become a major portion of most dermatologists' practice. An ever-increasing array of therapeutic...

The use of terbinafine in the treatment of onychomycosis in adults and special populations: a review of the evidence.
May 1, 2005... Abstract Terbinafine is an allylamine with fungicidal activity, first approved for the treatment of onychomycosis in the United Kingdom in the early 1990s, and in the US in 1996. Terbinafine is the most frequently prescribed oral...

The effect of lidocaine and adrenaline on the viability of injected adipose tissue--an experimental study in nude mice.
May 1, 2005... Abstract Adipose tissue injection as a free graft for the correction of soft tissue defects is a widespread procedure in plastic surgery. The main problem in achieving long-term soft tissue augmentation is partial absorption of the...

The potential of interleukin 12 inhibition in the treatment of psoriasis.
May 1, 2005... Abstract Interleukin 12 (IL-12) is an important cytokine produced by a variety of immune effector cells that leads to a type 1 helper T cell (Th1) response. IL-12 also directs T cells to the skin via induction of cutaneous lymphocyte...

Rosacea, light, and phototherapy.
May 1, 2005... Abstract The long-established notion that rosacea is worsened by light is of particular concern in the phototherapy of diseases such as psoriasis, eczema, or vitiligo, which often can be coexistent with rosacea. A literature search was...

Clobetasol propionate 0.05% lotion in the treatment of moderate to severe atopic dermatitis: a randomized evaluation versus clobetasol propionate emollient cream.
May 1, 2005... Abstract Atopic dermatitis (AD) is a chronic inflammatory and pruritic skin disorder marked by alternating periods of relapse and remission. This multicenter, randomized, active- and vehicle-controlled, investigator-blinded study compared...

A randomized controlled clinical trial assessing the effect of betamethasone valerate 0.12% foam on the short-term treatment of stasis dermatitis.
May 1, 2005... Abstract Background: There are no published studies examining either the effectiveness of topical steroids in the treatment of stasis dermatitis or indicating what steroid strength or duration of treatment is optimal to treat this common...

Evaluation of subcision as a treatment for cutaneous striae.
May 1, 2005... Abstract Background: Treatment options for cutaneous striae are very limited. Objective: To determine if subcision is an effective treatment for cutaneous striae and compare a combination with 0.1% tretinoin cream against a single...

Basal cell carcinoma of the areola in a man.(CASE REPORTS)
May 1, 2005... Abstract Basal cell carcinomas (BCCs) that arise in sun-protected sites are quite uncommon. We report a case of BCC of the areola, which is extremely rare. Mohs micrographic surgery was used for the treatment. The etiologic factors of BCCs...

Merkel cell carcinoma in a patient with autoimmune hepatitis.(CASE REPORTS)
May 1, 2005... Abstract Merkel cell carcinoma (MCC) has been shown to have a higher incidence in many etiologically distinct immunosuppressed populations. We report a case of aggressive MCC diagnosed in a man with autoimmune hepatitis who was treated...

The successful use of etanercept in combination therapy for treatment of acrodermatitis continua of Hallopeau.(CASE REPORTS)
May 1, 2005... Abstract Acrodermatitis continua of Hallopeau (ACH) is a rare form of pustular psoriasis which poses a challenge to treat and causes considerable pain and suffering for those afflicted. Tumor necrosis factor-alpha (TNF-[alpha]) is a...

Furuncular myiasis secondary to Dermatobia hominis.(CASE REPORTS)
May 1, 2005... Abstract Dermatobia homininis is the most common cause of furuncular myiasis in Central and South America. It is diagnosed based on a history of travel to an endemic region and the characteristic cutaneous lesion. We present a 54-year-old...

Isotretinoin in acne vulgaris: a prospective analysis of 160 cases from Kuwait.(CASE REPORTS)
May 1, 2005... Abstract A total of 160 patients (59 male and 101 female) ages varying from 13 to 28 years (mean age 20 years) with moderate to severe acne were treated with isotretinoin in the doses ranging from 0.5 mg/kg/day to 1 mg/kg/day. The drug was...

Clofazimine as elective treatment for granulomatous cheilitis.(CASE REPORTS)
May 1, 2005... Abstract Cheilitis granulomatosa (CG) is a rare, idiopathic inflammatory disorder that usually affects young adults and clinically is characterized by diffuse, non-tender, soft to firm swelling of one or both lips. A variant of...

Focus on: herpes acquisition and transmission.
May 1, 2005... Abstract Present dogma is based on herpesviruses (HSV-1 and HSV-2) residing only in the dorsal root ganglion and laying dormant unless reactivated. Polymerase chain reaction has improved specificity and sensitivity so that tenets based on...

Treatment and prophylaxis of seborrheic dermatitis of the scalp with antipityrosporal 1% ciclopirox shampoo.(WASHINGTON WHISPERS)
May 1, 2005... Treatment and Prophylaxis of Seborrheic Dermatitis of the Scalp with Antipityrosporal 1% Ciclopirox Shampoo Shuster S, et al. Archives of Dermatology. 2005;141:47-52. Summary The authors present a double-blinded, randomized,...

Topical tacrolimus ointment combined with 6% salicylic acid gel for plaque psoriasis treatment.(WASHINGTON WHISPERS)
May 1, 2005... Topical Tacrolimus Ointment Combined with 6% Salicylic Acid Gel for Plaque Psoriasis Treatment Carroll CL, et al. Archives of Dermatology. 2005;141:43-46. Summary The authors present a randomized, vehicle-controlled, left-right...

Hydrocortisone butyrate 0.1% cream in the treatment of chronic dermatitis.(WASHINGTON WHISPERS)
May 1, 2005... Hydrocortisone Butyrate 0.1% Cream in the Treatment of Chronic Dermatitis Fowler JF, et al. Cutis. 2005; 75(2):125-131. Summary The authors present a double-blinded, multicenter, randomized clinical trial to assess the efficacy...

No compensatory sweating after botulinum toxin treatment of palmar hyperhidrosis.(WASHINGTON WHISPERS)
May 1, 2005... No Compensatory Sweating after Botulinum Toxin Treatment of Palmar Hyperhidrosis Krogstad AL, et al. British Journal of Dermatology. 2005;152:329-333. Summary The authors present a trial to determine if treating palmar...

Topical aminolevulinic acid-based photodynamic therapy as a treatment option for psoriasis? Results of a randomized, observer-blinded study.(WASHINGTON WHISPERS)
May 1, 2005... Topical Aminolevulinic Acid-Based Photodynamic Therapy as a Treatment Option for Psoriasis? Results of a Randomized, Observer-Blinded Study Radakovic-Fijan S, et al. British Journal of Dermatology. 2005;152:279-283. Summary The...

Centocor files sBLA for infliximab.(PIPELINE PREVIEWS)
May 1, 2005... Based on promising results of 2 double-blind, placebo-controlled trials, IMPACT and IMPACT 2, a Supplemental Biologics Licensee Application (sBLA) was accepted by the FDA for infliximab (Remicade[R]). Infliximab is a monoclonal antibody to TNF...

FDA approves vaccinia-specific IgG injection (VIGIV) for complications of smallpox vaccination.(PIPELINE PREVIEWS)
May 1, 2005... The FDA recently approved a human plasma-derived antibody product (Vaccinia Immune Globulin Intravenous; VIGIV) made by DynPort Vaccine Company, LLC) for the treatment of complications arising from administration of smallpox vaccination. The...

Fluocinonide 0.1% cream (Vanos) approved for plaque-type psoriasis.(PIPELINE PREVIEWS)
May 1, 2005... Patheon Inc. announced FDA approval of Vanos[R] (fluocinonide 0.1%) cream for the treatment of plaque-type psoriasis affecting up to 10% body surface area. Vanos is a class 1 corticosteroid formulated for once or twice daily application....

Generic 750 mg levofloxacin (Levaquin[R]) for bacterial infections in adults.(PIPELINE PREVIEWS)
May 1, 2005... A first-time generic formulation of 750 mg levofloxacin tablets (Levaquin, Ortho-McNeil Pharmaceuticals, Inc.) has been approved by the FDA. Levofloxacin is a fluoroquinolone antibiotic and is currently indicated for various infections in...

New Drug Application submitted for dalbavancin for treatment of skin infections.(PIPELINE PREVIEWS)
May 1, 2005... Vicuron Pharmaceuticals Inc. announced recently that it has submitted a New Drug Application (NDA) to the FDA for IV dalbavancin for the treatment of complicated skin and soft tissue infections (cSSTIs). Dalbavancin is a second-generation...

Second-generation pulsed light system (Ellipse I2PL) receives FDA approval.(PIPELINE PREVIEWS)
May 1, 2005... The Ellipse I2PL, manufactured by Candela Corp, has received FDA approval for the improvement of pigmentary, vascular, and textural changes in sun damaged skin. According to the manufacturer, the Ellipse allows effective treatments of both...

FDA warns of illegal home medical test kits.(PIPELINE PREVIEWS)
May 1, 2005... The FDA sent an alert warning consumers against the use of unapproved home medical testing kits marketed over the Internet by Globus Media of Montreal, Canada according to MedWatch, the FDA's adverse event reporting and safety information...

Oracea enters Phase III clinical trials.(PIPELINE PREVIEWS)
May 1, 2005... Screening and enrollment of over 500 patients has been completed for two multicenter, double-blind, placebo-controlled Phase III clinical trials evaluating the efficacy of Oracea[R] (doxycycline) for the treatment of rosacea. Oracea is a...

New indication for Smoothbeam diode laser.(PIPELINE PREVIEWS)
May 1, 2005... Candela Corporation has announced that it received clearance from the FDA to market the Smoothbeam diode laser for the treatment of sebaceous hyperplasia. This is the fifth indication for this laser system. Other indications include treatment...

FDA warns of Zyprexa[R] and Zyrtec[R] substitution errors.(PIPELINE PREVIEWS)
May 1, 2005... Reports of medication dispensing or prescribing errors involving Zyprexa (olanzapine; Eli Lilly & Co.) and Zyrtec (ceterizine HCl; Pfizer, Inc.) have led to an official FDA warning to healthcare professionals according to an alert from MedWatch...

Bioengineered skin and wound healing.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). This study will look at whether a graft of bioengineered skin (BSC), known commercially as Apligraf[R],...

Comparison of telavancin and vancomycin for complicated skin and skin structure infections with a focus on methicillin-resistant staphylococcus aureus.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by Theravance. Study 0017 compares the safety and effectiveness of an investigational drug, telavancin, and an approved drug, vancomycin, for the treatment of complicated skin and skin...

T4N5 liposomal lotion in preventing the recurrence of nonmelanoma skin cancer in patients who have undergone a kidney transplant.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsors and Collaborators: UAB Comprehensive Cancer Center and National Cancer Institute (NCI). This randomized phase II trial is studying how well T4N5 liposomal lotion works in preventing the...

Photodynamic therapy using silicon phthalocyanine 4 in treating patients with actinic keratosis, Bowen's disease, skin cancer, or stage I or stage II mycosis fungoides.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsors and Collaborators: Ireland Cancer Center and National Cancer Institute (NCI). This phase I trial is studying the side effects and best dose of photodynamic therapy using silicon...

Photodynamic therapy in treating patients with skin cancer or solid tumors metastatic to the skin.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsors and Collaborators: Ireland Cancer Center and National Cancer Institute (NCI). Phase I trial to study the effectiveness of photo-dynamic therapy in treating patients who have either squamous...

Celecoxib in preventing skin cancer.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsors and Collaborators: Herbert Irving Comprehensive Cancer Center and National Cancer Institute (NCI). Randomized phase II trial to study the effectiveness of celecoxib in preventing skin cancer...

Linezolid in the treatment of complicated skin and soft tissue due to methicillin-resistant staphylococcus aureus.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by Pfizer. This is a Phase IV randomized, multi-center, open label trial to compare the clinical safety and efficacy of linezolid to vancomycin in the treatment of complicated skin and soft...

Daptomycin in the treatment of patients with renal insufficiency and complicated skin and skin structure infections.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by Cubist Pharmaceuticals. This is a Phase 4, randomized, open-label, multicenter, comparative study designed to further evaluate the pharmacokinetics of intravenous daptomycin and the...

The acquisition of blood and skin samples from normal volunteers to support research activities on dermatologic diseases.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Cancer Institute (NCI). This protocol is concerned with the acquisition of blood, skin, and mucosal samples from normal volunteers to support the basic science research...

Photodynamic therapy in treating patients with skin cancer.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by Roswell Park Cancer Institute. This randomized phase II trial is studying how well photodynamic therapy works in treating patients with skin cancer. Condition ...

Photodynamic therapy in treating patients with skin cancer.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsors and Collaborators: Roswell Park Cancer Institute and National Cancer Institute (NCI). This randomized phase II trial is studying how well photodynamic therapy that includes aminolevulinic...

ZD1839 (Iressa[R]) for recurrent or metastatic squamous cell carcinoma of the skin.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by M.D. Anderson Cancer Center. Patients will receive 250 mg ZD1839 daily by mouth (1 course = 4 weeks). Patients will receive 6 courses of treatment. A patient may continue to receive...

Characterizing serum protein patterns in selected skin diseases.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Cancer Institute (NCI). The purpose of this study is to determine whether computer-aided analysis of proteins found in the blood can distinguish between the serum protein...

Oral acyclovir for neonatal HSV disease of the skin, eyes, and mouth.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Institute of Allergy and Infectious Diseases (NIAID). The purpose of this study is to test whether long-term treatment with oral acyclovir improves the outcome for infants with...

Topical imiquimod compared with surgery in treating patients with basal cell skin cancer.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by Cancer Research UK. Randomized phase III trial to compare the effectiveness of topical imiquimod with that of surgery in treating patients who have basal cell skin cancer. ...

Examination of clinical and laboratory abnormalities in patients with defective DNA repair: xeroderma pigmentosum, Cockayne syndrome, or trichothiodystrophy.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Cancer Institute (NCI). Four rare genetic diseases, xeroderma pigmentosum (XP), Cockayne syndrome (CS), the XP/CS complex and trichothiodystrophy (TTD) have defective DNA...

Tetracycline in preventing skin rash in patients who are receiving drugs such as gefitinib and cetuximab for cancer.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsors and collaborators: North Central Cancer Treatment Group and National Cancer Institute (NCI). This randomized clinical trial is studying tetracycline to see how well it works compared to...

Infliximab (Remicade[R]) to treat dermatomyositis and polymyositis.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). This study will examine whether infliximab (Remicade[R]) is safe and effective for the treatment of...

Cancer risk in carriers of the gene for xeroderma pigmentosum.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Cancer Institute (NCI). This study will determine if family members of patients with xeroderma pigmentosum (XP) have various abnormalities, including: skin abnormalities;...

Skin response to sunlight.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Cancer Institute (NCI). This study will explore the relationship between skin cancer and ultraviolet (UV) radiation exposure by measuring gene expression patterns in skin that...

Study of skin tumors in tuberous sclerosis.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Heart, Lung, and Blood Institute (NHLBI). Tuberous sclerosis is a rare, hereditary disease in which patients develop multiple tumors. Although not cancerous, the tumors can...

Evaluation and treatment of patients with dermatologic diseases.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Cancer Institute (NCI). This is a training, natural history of disease, and screening protocol for the evaluation, treatment and follow-up of patients with dermatologic diseases...

Serum protein patterns in participants with mycosis fungoides/cutaneous T-cell lymphoma, psoriasis, or normal skin.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Cancer Institute (NCI). Pilot study to evaluate the effectiveness of analyzing blood proteins in detecting mycosis fungoides/cutaneous T cell lymphoma. Condition ...

Study of talabostat in advanced melanoma.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by Point Therapeutics. The purpose of this study is to assess the antitumor activity and safety of talabostat in patients with metastatic melanoma. Condition Treatment or...

Study of talabostat and cisplatin in advanced melanoma.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by Point Therapeutics. The purpose of this study is to assess the antitumor activity and safety of the combination of talabostat and cisplatin in patients with metastatic melanoma. ...

Genetic analysis of familial keloids.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The purpose of this study is to identify the gene or genes responsible for keloid formation. Keloids are raised...

To study the effects of CD25 and low dose cyclosporin in the treatment of active psoriasis vulgaris.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by Protein Design Labs. This study compares the efficacy and analyzes the cellular effects of anti-TAC (daclizumab) and cyclosporine in the treatment of psoriasis vulgaris. This is a...

To study the use of humanized CD25 in preventing the relapse of psoriasis vulgaris.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by Protein Design Labs. This study is designed to study disease relapse after NBUVB and how the administration of daclizumab/placebo alters disease relapse. Condition Treatment or...

Clinical, laboratory, and epidemiologic characterization of individuals and families at high risk of melanoma.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Cancer Institute (NCI). This study will investigate how genetic and environmental factors contribute to the development of melanoma, a type of skin cancer, and related...

Copper histidine therapy for Menkes diseases.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Institute of Neurological Disorders and Stroke. The purpose of this study is to continue to evaluate the effects of early copper histidine in Menkes disease patients and to...

Phase II randomized bilateral comparison of topical Targretin[R] gel 1% in alopecia areata.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsors and Collaborators: M.D. Anderson Cancer Center and Ligand Pharmaceuticals. The rationale for the use of bexarotene in alopecia areata comes from the drugs' immunomodulatory effects. It has...

Preliminary testing of new treatment for chronic leg wounds.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsors and Collaborators: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and National Gene Vector Laboratory. The long-term goal of this study is to evaluate a new...

Conditioning, the placebo effect, and psoriasis.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). This study uses the psychological principle known as classical conditioning to try to improve the standard...

Alopecia areata registry.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). Alopecia areata is the loss of hair in oval patches that can proceed to loss of all hair (alopecia totalis...

Bevacizumab to treat Kaposi's sarcoma in HIV-positive and HIV-negative patients.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by National Cancer Institute (NCI). This study will examine the safety and effectiveness of the experimental drug bevacizumab for treating both non-AIDS and AIDS-associated Kaposi's sarcoma...

An investigational vaccine in reducing the incidence of anogenital warts in young men.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by Merck. This study is to evaluate an investigational vaccine with the following objectives: 1) To demonstrate that the vaccine is well-tolerated in young men; 2) To demonstrate that the...

An observational study of the use and safety of Raptiva[R] during pregnancy.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by Genentech. The Raptiva Pregnancy Registry is a prospective observational study established to obtain data on pregnancy outcomes of women who are exposed to Raptiva. Condition...

Study of oral zileuton in the treatment of moderate to severe facial acne vulgaris.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsored by Critical Therapeutics. Tissue inflammation is a major component of the acne disease process. Leukotriene B4 (LTB4) is thought to be a major player in the development of tissue...

Photodynamic therapy in treating patients with lymphoma or chronic lymphocytic leukemia.(CLINICAL TRIAL REVIEW)
May 1, 2005... This study is currently recruiting patients. Sponsors and Collaborators: Roswell Park Cancer Institute. Randomized phase II trial to study the effectiveness of photodynamic therapy using aminolevulinic acid in treating patients who have...

The ABCDEs of melanoma: an evolving concept.(SKIN CANCER FOUNDATION UPDATE)
May 1, 2005... In 1985, (1,2) clinicians working in the Melanoma Clinical Cooperative Group at New York University (NYU) School of Medicine sought to develop easily memorizable, readily usable guidelines to alert both laypersons and primary care providers to...