Journal of Drugs in Dermatology articles from June 2008

Journal of Drugs in Dermatology archives from June 2008

Letter from the Guest Editor.(Guest editorial)
June 1, 2008... Here we are again... the Acne and Rosacea issue of Journal of Drugs in Dermatology, this time in 2008.I am very thankful to Dr. Perry Robins and the leadership of this publication for the opportunity to contribute each year as the Guest Editor...

Evaluating hyperandrogenism: a challenge in acne management.(Disease/Disorder overview)
June 1, 2008... Introduction Androgen hormones play a pivotal role in the multifactorial pathogenesis of acne vulgaris, proven by both direct and indirect evidence. For example, acne begins to develop at adrenarche, when androgen hormone production...

American acne & rosacea society rosacea medical management guidelines.
June 1, 2008... Objectives The objectives of these Guidelines are to provide an overview of the fundamental disease state of rosacea and quality of life implications and outline available pharmacological treatments for rosacea with reference to supporting...

Solubilized Benzoyl peroxide versus Benzoyl peroxide/clindamycin in the treatment of moderate acne.(Clinical report)
June 1, 2008... Abstract Background: Benzoyl peroxide (BPO) is poorly soluble. A solubilized formulation of BPO has been developed to maximize its bioavailability and enhance follicular penetration Methods: Patients with acne vulgaris were randomly...

Azelaic acid 15% gel once daily versus twice daily in papulopustular rosacea.(Clinical report)
June 1, 2008... Abstract Background: Twice-daily azelaic acid (AzA) is the conventional regimen for papulopustular rosacea, but once-daily AzA may be equally effective, with greater convenience and dosing flexibility. In order to test this hypothesis, an...

Steroid acne and rebound phenomenon.(Clinical report)
June 1, 2008... Abstract Background: There have been many reports of topical steroids treatment for the face causing perioral dermatitis, steroid acne, and steroid rebound phenomenon. Objective: To assess patient reported outcomes in patients...

Prevalence and severity of facial and truncal acne in a referral cohort.(Clinical report)
June 1, 2008... Abstract Background: There is a paucity of information on the prevalence and severity of acne of the face, chest, and back. Purpose: This study was designed to examine the prevalence and severity of acne on the face, chest, and back in...

The effect of HESA-A on psoriasis vulgaris.(Clinical report)
June 1, 2008... Abstract Background: Psoriasis vulgaris is one of the most common chronic skin disorders without any curative treatment. The aim of this study was to investigate the efficacy and safety of HESA-A in the treatment of psoriasis. ...

Psoriasis and the metabolic syndrome.(Clinical report)
June 1, 2008... Abstract Psoriasis is a chronic immune-inflammatory-mediated disease that can predispose patients to other inflammatory conditions. For example, individuals with psoriasis are at increased risk for insulin resistance, obesity,...

Comparison of anti-inflammatory dose doxycycline versus doxycycline 100 mg in the treatment of rosacea.(Clinical report)
June 1, 2008... Rosacea is a chronic inflammatory dermatosis, but the exact etiology of rosacea remains unknown. It has been described as a result of "a disparate assortment of stimuli acting in concert on a genetically susceptible host" with a constitutional...

Case reports: nodule formation following lip augmentation using porcine collagen-derived filler.(Case study)
June 1, 2008... Abstract In 2006, a novel, porcine-derived collagen filler (Evolence) was introduced to the Canadian aesthetic market. Evolence, unlike bovine-derived collagen, does not require skin testing and was marketed as an alternative to hyaluronic...

Case reports: unilateral facial paralysis after treatment of secondary syphilis.(Case study)
June 1, 2008... Abstract Bell's palsy is an acute facial paralysis of unknown etiology. Infections including syphilis have been implicated as causes for peripheral facial paresis. The Jariseh-Herxheimer reaction is an acute worsening of skin...

Case reports: severe exacerbation of rosacea induced by cinnamon supplements.(Case study)
June 1, 2008... Abstract The authors report a case of a 68-year-old Caucasian female with type 2 diabetes mellitus who experienced an acute exacerbation of her rosacea 2 weeks after self-initiating cinnamon oil pills to lower her blood sugar levels....

Case reports: sorafenib-induced palmoplantar hyperkeratosis.(Case study)
June 1, 2008... Abstract Sorafenib is an oral multikinase. inhibitor used in the treatment of renal cell carcinoma. As with single kinase inhibitors, cutaneous adverse events have been reported with sorafenib, specifically a hand-foot reaction complicated...

CASE REPORTS: benzoyl peroxide microsphere cream as monotherapy and combination treatment of acne.(Case study)
June 1, 2008... Abstract This office-based case series describes the use of a new formulation of benzoyl peroxide (BPO) delivered via a porous microsphere cream vehicle in patients with mild to moderate acne vulgaris. While BPO has been used for many...

News, views, and reviews.(Clinical report)
June 1, 2008... News, Views, and Reviews provides focused updates, topic reviews, and editorials concerning the latest developments in dermatologic therapy. Management of Methicillmrresistant Staphylococcus aureus (MRSA) Skin Infections and MRSA...

Pipeline previews.
June 1, 2008... Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatological community. These features may include additional information from the manufacturers, plus reports from...

Clinical trial review.
June 1, 2008... Clinical Trial Review is designed to provide physicians with as much information as possible about drugs undergoing Phase 1,.2, and 3 clinical testing. It is our goal to inform the reader of the up-to-date status of these drug trials before...

Instructions to authors: may be downloaded at www.JDDonline.com/submit.php.
June 1, 2008... All submissions must he clearly marked as articles (recommended: 20004000 words, including references and tables), case reports (750-1500 words plus pictures), or letters (700 words max, no figures or references). You may submit either by...

Introduction.(Column)
June 1, 2008... When I was asked to author the introduction to this supplement of the Journal of Drugs in Dermatology, I accepted without hesitation. The opportunity to review, evaluate, and discuss new clinical information about treatment of the most common...

Efficacy and tolerability of adapalene 0.3% gel compared to tazarotene 0.1% gel in the treatment of acne vulgaris.(Clinical report)
June 1, 2008... Abstract Treatment of acne vulgaris can be challenging for both patients and physicians. Topical retinoids are often considered first-line therapy for the treatment of all but the most severe forms of acne. A variety of formulations of...

Is switching retinoids a sound strategy for the treatment of acne vulgaris?(Clinical report)
June 1, 2008... Abstract Topical retinoids, such as adapalene gel and tazarotene cream, are considered first-line therapy for the treatment of acne vulgaris. Dermatologists often initiate adapalene gel treatment first, due to its good tolerability,...

Adapalene 0.1% gel compared to tazarotene 0.1% cream in the treatment of acne vulgaris.(Clinical report)
June 1, 2008... Abstract A variety of topical retinoids is available for the treatment of acne vulgaris. Selection of the appropriate treatment depends not only on efficacy but also on how well the patient can tolerate different formulations. The goal of...

Long-term safety and efficacy study of adapalene 0.3% gel.(Clinical report)
June 1, 2008... Abstract The efficacy and safety of adapalene 0.1% gel in the treatment of acne vulgaris has been demonstrated in multiple controlled clinical trials; A higher concentration formulation, adapalene 0.3% gel, has been developed to provide a...