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Keeping science Kosher: in-the-lab realities of federal stem cell policy.
September 1, 2007... [ILLUSTRATION OMITTED]
Meri Firpo still laughs when someone asks her about the pens.
Last year, a Los Angeles Times article proclaimed that Dr. Firpo, a stem cell researcher at the University of Minnesota, required that workers in her...
Methods most often used by Bioscience Technology readers.(SNAPSHOT)
September 1, 2007...
Methods Most Often Used by
Bioscience Technology
Readers
Microscopy 69%
Spectrophotometry 64%
Cell Culture 48%
PCR 45%
ELISA/Immunoassay 44%
HPLC ...
Humbling news.(scientist involvement in environmental policy making)(Editorial)
September 1, 2007... During the Monday, September 10th edition of National Public Radio's Morning Edition program, Steve Inskeep interviewed Bjorn Lomborg. Lomborg, a Ph.D. in political science, and the director of the Copenhagen Consensus Center and an adjunct...
Benchtop enzymatic assay systems.(September's Innovations)
September 1, 2007... LabChip EZ Reader Series systems cost-effectively profile compounds against a diverse kinase panel. The base system features a four-sipper LabChip microfluidic device, while the EZ Reader II system is offered with a choice of either a 4-sipper...
Plating module.(September's Innovations)
September 1, 2007... The Advanced Plating Module (APM) is an option for automating media changes in microplates on the CompacT Select (The Automation Partnership, Wilmington, DE) automated cell culture system. The APM option includes a C[O.sub.2] cell culture...
Pipette-type transfection device.(September's Innovations)
September 1, 2007... OneDrop MicroPoration MP-100 System uses sample sizes of 10 to 100 [micro]l and provides high yields of transfected cell. The hand-held pipette-type device utilizes MicroPoration technology, and consists of a pulse generator, safety chamber and...
Multifunction microscope.(September's Innovations)
September 1, 2007... [ILLUSTRATION OMITTED]
With a new turret condenser and motorized nosepiece, the LV-UDM multifunctional microscope can be used in various bioscience applications with changing hardware. Advanced illumination techniques for both transmitted...
Small syringe pump.(September's Innovations)
September 1, 2007... [ILLUSTRATION OMITTED]
Model KDS 310 Nano Pump is used exclusively with micro syringes from 0.5 to 250 microliter. The pump head can be mounted close to the fluid delivery location while the control unit can be located up to six feet away....
Two-compartment disposable bioreactor.(September's Innovations)(Brief article)
September 1, 2007... Disposable CELLine bioreactor maintains cell cultures at near in vivo conditions. The system incorporates two compartments separated by a 10 kDa MWCO membrane to provide continuous and optimal levels of oxygen and nutrients to cultures while...
HEPA-Filtered Glove Boxes.(September's Innovations)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
Precise HEPA-Filtered Glove Boxes protect operators from hazardous airborne particulates and powders. The units feature a one-piece molded, medium-density polyethylene shell with a black, chemical-resistant work...
High throughput rat, mouse genotyping.(September's Innovations)
September 1, 2007... Taconic has announced a high throughput platform for genotyping laboratory mice and rats. Scientists log-in to http://taconic.transnetyx.com and request a sample collection kit by clicking on the "Quick Order" button. Sample submission and...
Purdue researchers develop technology to detect cancer by scanning surface veins.(Research News)
September 1, 2007... A new technology for cancer detection that eliminates the need for drawing blood has been developed by researchers at Purdue University's Cancer Center, Department of Chemistry and Weldon School of Biomedical Engineering, in collaboration with...
Stem cells isolated in womb tissue.(Research News)
September 1, 2007... Scientists in Australia have found a way of identifying probable stem cells in the lining of women's wombs. The finding opens up the possibility of using the stem cells for tissue engineering applications such as building up natural tissue to...
Measurement of zebrafish QT prolongation.(Research News)(Phylonix pharmaceutical Inc. contracred with ADInstruments)(PowerLab systems)(Brief article)
September 1, 2007... PowerLab systems from ADInstruments (Colorado Springs, Colorado) are being used to establish the zebrafish as a model for assessing drug effects on cardiac function, using QT prolongation as a key indicator. Researchers at Phylonix...
New class of RNA may be important in human cancer.(Research News)
September 1, 2007... Research conducted at The Ohio State University Medical Center shows that an obscure form of RNA, part of the protein-making machinery in all cells, might play an important role in human cancer. These ultraconserved noncoding RNAs (UCRs) have...
Amplification reagents.(DNA Focus)
September 1, 2007... These reagents are formulated for use in reverse transcription, PCR, and real-time PCR, to help achieve success with minimal optimization in nucleic acid amplification applications. The reverse transcription products facilitate amplification of...
DNA Methylation kit.(DNA Focus)
September 1, 2007... EZ DNA Methylation-Direct kit provides bisulfite conversion of DNA directly from blood, tissue, or cells. Prior purification steps are not required. The streamlined procedure enables the complete conversion of DNA directly from as few as 10...
Non-mutagenic DNA stain.(DNA Focus)
September 1, 2007... [ILLUSTRATION OMITTED]
ENVISION non-mutagenic fluorescent DNA stain (Amresco, Inc., Solon, OH) is supplied in the firm's 6 X loading buffer. The fluorescent reagent forms a complex with the sample DNA before electrophoresis. Bands are...
RNA, DNA and protein purification.(DNA Focus)
September 1, 2007... [ILLUSTRATION OMITTED]
The Urine (exfoliated cell) RNA Purification Kit and Urine (Exfoliated Cell) DNA Purification Kit enable isolation of total RNA or genomic DNA from exfoliated cells that have been shed into the urine from the urinary...
Expedited analysis and purification of a GST-tagged recombinant protein: synergistic application of two disparate technologies.(Biochemicals & Kits)
September 1, 2007... Introduction
The use of affinity tags for purification of recombinant proteins is a widely accepted technique. One of the more commonly employed tags is glutathione Stransferase (GST). Protein fused to GST can be purified from crude...
Synthetic extracellular matrix.(Product News)(Glycosan BioSystems Inc. information)(Extracel-X hydrogel)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
Extracel-X hydrogel is an easy to use hyaluronan-based synthetic extracellular matrix for preparing tumor xenografts in mice. It is lactate dehydrogenase- elevating virus (LDEV) free. To reconstitute the hydrogel,...
Protein microarrays.(Product News)
September 1, 2007... SomaPlex slides, for screening protein biomarkers in human tumors, are arrays prepared from a vast collection of total protein lysates derived from numerous human tissues representing a range of cancer subtypes. Clinical and histopathology is...
Full-length, biologically-relevant mTOR.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
The mTOR kinase has recently been linked to many important human diseases, including cancer, diabetes, obesity, cardiovascular disease ad neurological disorders. The kinase enables the regulation of cell cycle...
cDNA clones.(Product News)
September 1, 2007... The TrueClone Access Collection is comprised of 5000 expression-ready full-length cDNA clones that enable single-target analysis and a systems biology approach to high-throughput screening, functional studies, and protein production. The cDNA...
Universal electroporation buffer.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
Gene Pulser electroporation buffer is formulated to improve delivery of molecules into mammalian cells; especially primary cells and difficult-to-transfect cells. The sugar-based formulation simulates the natural...
Human Adipose-Derived Stem Cells.(Product News)
September 1, 2007... Poietics Human Adipose-Derived Stem Cells (ADSC), for use adult stem cell research, provide labs with ready to use cells and media for research in areas such as tissue repair, wound healing, cell differentiation, osteoporosis, insulin...
Non-enzymatic FFPE tissue labeling.(Product News)
September 1, 2007... These kits enable oligo microarray comparative genomic hybridization (CGH) analysis of DNA from formalin-fixed paraffin-embedded (FFPE) tissue samples. The method is based on proprietary Universal Linkage System (ULS) technology, non-enzymatic...
Protein assays.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
LifeMarker protein assays quantify proteins from complex biological samples without the need for an antibody. The assays can be multiplexed to monitor a panel of protein markers. The assays are currently available...
Antibody microarray.(Product News)
September 1, 2007... XPRESS Profiler725 contains 725 antibodies that are arrayed in duplicate on nitrocellulose slides and compatible with the majority of available DNA array scanners. The arrays detect human, mouse, and rat proteins associated with various cell...
Antigen immobilization immunoassay.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
Dynabeads M-270 Immunoassay (Carboxyl) immobilizes antigens such as proteins, peptides, steroids and hormones for in vitro diagnostic (IVD) magnetic bead-based immunoassay applications. The antigens are coupled...
Transgenic, knock-out and knock-in mice.(Product News)
September 1, 2007... TransnetYX's technologies for automated genetic testing and Internet biopsy submission and results reporting speeds the process while ensuring quality and accuracy of test results for transgenic, knock-out and knock-in mutant mice. The use of...
Human genome sequencing.(Sequencing Focus)
September 1, 2007... [ILLUSTRATION OMITTED]
The Genome Analyzer uses sequencing-by-synthesis chemistry, enabling a human genome to be sequenced for a greatly reduced cost. Producing over 100 times the output of other analyzers enables researchers to carry out...
Real-Time PCR System.(Sequencing Focus)
September 1, 2007... [ILLUSTRATION OMITTED]
StepOne Real-Time PCR System provides highly-functional, easy-to-use and cost-effective way to conduct real-time PCR experiments. Real-time PCR is a laboratory method used to simultaneously detect and determine the...
Genome sequencer.(Sequencing Focus)
September 1, 2007... FLX System high-throughput sequencing instrument can be used in applications including identification of small RNAs, ChIP-sequencing, whole genome sequencing, metagenomics and amplicon resequencing. As many as 100 million bases can be sequenced...
Gel documentation system.(Sequencing Focus)
September 1, 2007... [ILLUSTRATION OMITTED]
The DigiGenius gel documentation system features a 10 mega pixel camera that can separate even the closest band images. The camera can be linked via standard interface to a PC or Mac, for full automation of camera...
Computer simulation of molecular docking to screen compounds.(Instruments & Systems)
September 1, 2007... Introduction
Peptide fusion inhibitors based on C-helix regions of the human immunodeficiency virus (HIV) viral protein gp41 represent an important new class of antiviral therapeutics. However peptides are not ideal drugs. They are...
Sequence analysis.(Product News)(DNASTAR Inc. product information )(Lasergene)(Brief article)
September 1, 2007... Lasergene is a comprehensive suite of tools for molecular biologists and geneticists, and is used primarily in the assembly and analysis of DNA and protein sequences. Version 7.2 offers expanded assembly and visualization capabilities. The...
Library storage, delivery.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
The comPOUND automated sample storage system utilizes high-speed cherry-picking to select library subsets, and can deliver any sample within five seconds. Sample integrity is maintained using a hermetically sealed...
Real-time PCR system.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
The 96-well StepOnePlus System offers fluorophore detection chemistries including FAM/SYBR Green I, VIC/JOE, ROX and TAMRA dyes, and performs both standard and fast thermal cycling for any real-time PCR application,...
96-well plate for microscopy.(Product News)
September 1, 2007... This 96-well plate has a thin bottom that makes it useful for high resolution microscopy assays. The bottom has the same thickness as the original company slides, which is the same as a #1.5 cover slip. The plate is used exactly the same way...
Universal interface for continuous flow isotope ratio MS.(Product News)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
ConFlo IV Universal Interface, for liquid and gas chromatographs coupled with isotope ratio mass spectrometers, enables immediate switching between as many as three sample preparation devices to reduce idle time and...
Peak analysis software.(Product News)
September 1, 2007... Chart software module for use with PowerLab data acquisition systems (ADInstruments, Colorado Springs, CO) speeds up and enhances analysis of peaks in waveform data for life science researchers. The software can be used in a applications...
Biomarker discovery software.(Product News)
September 1, 2007... GeneSpring MS 1.1 allows for the import of data produced by the proprietary 6410 Triple Quadrupole (QQQ) liquid chromatography/mass spectrometer (LC/MS) system, enabling users to analyze QQQ quantitative batch result files with GeneSpring MS's...
Flow chemistry experimental system.(Product News)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
With the FRX, reactions occur under laminar flow conditions, improving reaction speed, optimization and control. The modular systems are configured to meet individual needs, and can be easily upgraded. Four FRX...
Integrated robotic system.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
Robotics systems for high-through-put applications utilize the Motoman HP3JC Robot as their transportation foundation, while SAMI Workstation EX Software provides features tailored to specific applications. A safety...
Stereomicroscope.(Product News)(Brief article)
September 1, 2007... SteREO Discovery.V20 incorporates a PlanApo S 2.3X objective to provide 1000 LP/mm resolution, with a maximum magnification of 345x (eyepieces 10x). Achromat S, Plan S and PlanApo S objective series enable fine details to be highlighted with...
Dual-Sample BeadChip.(Product News)
September 1, 2007... Infinium HumanHap550-Duo BeadChip provides the same content as the HumanHap550 BeadChip in a dual-sample for mat, increasing throughput and reducing sample costs. The chip contains more than 550,000 SNPs, selected based on a tag SNP approach...
Lab water purification.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
The compact arium EDI 61215 water purification system is offered for applications requiring Type 2 purified water. A combination of high flux reverse osmosis membranes with proven EDI (electrodeionization)...
Electrochemical HPLC.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
These HPLC systems electrochemically synthesize significant quantities of difficult-to-obtain metabolites from various parent compounds. The user can control the systems' oxidation capability to generate specific,...
Focus Drive with integrated controller.(Product News)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
Focus Drive with Integrated Controller, for optical microscopes, provides computer-controlled movement of the fine focus and retains manual movement of the coarse focus. No modification of the microscope is required...
Bioscience spell-check.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
Latest release of Spellex Biotech spell-checking software includes more than 200,000 specialty bioscience words and spelling engine enhancements. Correct choices are provided for incorrectly spelled words. Uncertain...
Drug testing and toxicology.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
GCMS-QP2010 Plus is equipped with three technologies that work with system hardware capabilities in identifying complex samples. AART (Automatic Adjustment of Retention Time) identifies and quantifies compounds after...
Educational microscope.(Product News)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
The E100 microscope provides clear, bright images. Chromatic-free infinity (CFI) optics correct for both chromatic aberration and curvature of the field of view. The result is a true-to-life, flat image right across...
Protein characterization.(Product News)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
Zetasizer Nano protein characterization instrument rapidly acquires data, so that the time-dependence of a process can be followed. The combination of dynamic and electrophoretic light scattering makes measurement of...
Analytical columns.(Product News)
September 1, 2007... ACQUITY-UltraPerformance LC (UPLC) HSS T3 columns feature high-strength 1.8 [micro]m silica particles. The first bonded phase to be introduced, T3, is aimed at separating small, water-soluble, polar organic molecules via reversed-phase UPLC...
Prevent waterborne contamination.(Water Purification Focus)
September 1, 2007... AquaTec water preservation cell prevents waterborne contamination in C[O.sub.2] incubators and water baths for up to six months. Protection is provided against more than 600 types of bacteria, viruses, molds and fungi. Harsh chemicals are not...
Water purification systems.(Water Purification Focus)
September 1, 2007... [ILLUSTRATION OMITTED]
PURELAB water purification systems feature multi-stage monitoring and purification technology that reduces annual costs. A complete system sanitization function reduces risk of bacterial contamination. Real-time TOC...
Life science water purification.(Water Purification Focus)
September 1, 2007... Cascada water purification system provides real-time quality monitoring for life sciences applications. Multi-stage monitoring analyzes water throughout system to ensure purity. Resistivity, temperature, and Total Organic Carbon (TOC)...
Low volume water purification.(Water Purification Focus)
September 1, 2007... The RiOs-DI Clinical water purification system is optimally used with low-volume analyzers requiring between 10-30 L purified water per day. It provides a reliable alternative to buying, storing and handling bottled water. The system combines...
Ergonomics and safety in biological research cabinets.(Apparatus & Consumables)
September 1, 2007... [FIGURE 1 OMITTED]
From the earliest forms of lab-acquired infections to the hazards posed by today's antibiotic-resistant bacteria and rapidly-mutating viruses, laboratories have had to eliminate risk. Many techniques produce aerosols...
Transducers monitor muscle contractions.(Product News)
September 1, 2007... With the attachment of these research-grade force transducers to the free end of the muscle, muscle contraction of small animals can be accurately measured. There are many configurations of transducers: isometric, isotonic, variable range and...
Multi-sample cell disrupter.(Product News)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
MiniBeadbeater-16 disrupts plant and animal tissues, spores, microorganisms and soil samples. Up to 16, 1.5 or 2 ml microvials in a removable cassette are loaded with small ceramic beads and sample suspension. The...
Benchtop centrifuge.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
Microfuge 16 has a small footprint, weighs just 14 pounds and is less than seven inches tall. The unit spins quietly at 16,163 x g (14,800 rpm) for pelleting or isolation of DNA, RNA, proteins and viruses. It can...
Heat shrink bands seal media bottles.(Product News)
September 1, 2007... The heat-shrink bands found on Nalgene PETG (polyethylene terephthalate copolymer) Square Media Bottles are now offered separately for customers that perform liquid fill operations. End users apply the recommended application torque, and the...
Conical Tube.(Product News)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
BD Falcon 50 ml Conical Tube with flip-top cap is used in any research applications requiring one-handed operations to open and close the cap. The design saves time and effort in applications requiring multiple...
Automated chemical synthesis.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
The reagent injection and product collection modules for the AFRICA (Automated Flow Reaction Incubation and Control Apparatus) system allow full automated synthesis, improving throughput and extending walk-away time....
Syringe filters.(Product News)
September 1, 2007... The 4 mm Millex syringe filter is available in sterile and nonsterile versions for use when filtering sample volumes
* Millipore Corp.
800-548-7853
www.millipore.com
Microcentrifuges.(Product News)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
Models 5418 and 5424 include standard aerosol-tight rotors that hold 18 or 24 microcentrifuge tubes, respectively. Unit lids optimize airflow and reduce noise levels. Operation is quiet even for runs that do not use...
New incubators.(Product News)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
The 6.0 cu/ft capacity Innova or Excella C[O.sub.2] incubators are heated from all six surfaces, creating gentle convection circulation and eliminating the need for a fan, and with it, the crevices where contaminants...
Processing cassette.(Product News)(Brief article)
September 1, 2007... In the first stage of fixation, MicrOflow II Mini Cassettes eliminate the need for containment materials that impede fluid flow. Openings on all four sides of the cassette walls allow maximum exposure to, and exchange of, processing reagents....
Upright freezers.(Product News)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
Revco PLUS -86 C upright freezers provide maximum heat removal capacity to ensure rapid temperature recovery after door openings. They consume power efficiently, which reduces heat emissions into the lab, meaning...
Modular Cleanroom.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
BioSafe Modular Cleanrooms meet cleanliness requirements to Class 10/ISO 3 at a fraction of the cost of conventional rooms. Their ultra-smooth stainless or powder-coated steel surfaces eliminate the cracks that can...
Automated Reactor Sampling System interface.(Product News)
September 1, 2007... Kits from Groton Biosystems (Boxborough, MA) permit the company's ARS Automated Reactor Sampling System to connect through a sterile interface to a variety of analytical instruments. Nutrient monitor interface options include kits for the YSI...
Silicone tubing for peristaltic pumps.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
Formulated for use in peristaltic pumps, APSPG tubing withstands repeated compression and release. Smooth surfaces allow uniform fluid flow and resist bacteria build-up. It is translucent and will not impart taste or...
Disposable reservoirs minimize reagent waste.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
These sterile, clear, disposable polystyrene reservoirs feature reusable bases. The units refract light so graduations below the fluid surface become invisible. Volume graduations are permanently marked on the inside...
High-speed low-vibration filter wheel.(Product News)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
The FW-1000 filter wheel features a rotary encoder provides positional feedback. Programmable filter sequences and delays are stored in memory. Motion can be triggered by a TTL input pulse as well as by standard...
Biomedical freezer.(Product News)(Brief article)
September 1, 2007... The MDF-U730M upright freezer is offered for long-term preservation and storage of specimens, biologics, reagents and test samples. The 24.4 cu/ft-capacity unit offers uniformity, microprocessor control and large flexible storage capacity for...
Multi-sample homogenizing system.(Product News)(Brief article)
September 1, 2007... Programmable Omni Prep homogenizer processes up to six samples per cycle and 250 samples per hour. Operation with disposable Omni Tip probes eliminates cross contamination and cleaning. Brushless motor technology provides quiet operation and...
Racks for plate handler.(Velocity11 introduces BenchCel Microplate Handling System and VStack Labware Stacker)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
Three different labware racks are offered for the BenchCel Microplate Handling System and VStack Labware Stacker. The existing economy rack will continue to be supplied as standard equipment. A slot-style rack will...
High capacity chilling/ heating dry baths.(Torrey Pines Scientific Inc. introduces EchoTherm Model IC35 Series Peltier dry baths)(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
EchoTherm Model IC35 Series Peltier-driven chilling/heating heavy-duty dry baths handle a large variety of sample blocks with the largest sample capacities available. The units are programmable and can store 5...
Pipetting Training and Certification Program.(Product News)
September 1, 2007... Improper pipetting technique is a major source of lab error. When working with smaller liquid volumes and more complex multipart tests, operator variability can have greater impact on results. The Pipetting Training and Certification Program...
Thermometer.(Control Co. introduces Traceable Pocket-Size Thermometer )(Brief article)
September 1, 2007... Traceable Pocket-Size Thermometer is compatible with all type-K probes. Temperature range is -50 to 750 C with a resolution of 1 degree and meter accuracy of [+ or -] 1 C + .75% between 0 to 500 C and [+ or -](1 C + 1%) 500 to 750C. Below 0...
Decontamination system.(Xenon Corp. introduces SteriPulse-XL Surface Sanitization System )(Brief article)
September 1, 2007... [ILLUSTRATION OMITTED]
SteriPulse-XL Surface Sanitization System employs pulsed UV light to achieve up to six log kill which kills DNA and prevents replication. The modular, non-contact system employs high peak energy lamps which destroy...
Square polycarbonate storage bottle.(Product News)
September 1, 2007... [ILLUSTRATION OMITTED]
Square polycarbonate bottles require less storage space than other bottles holding the same volume. These bottles are available in 125, 250 and 500 mL and 1L sizes, can be autoclaved one time at 121 C and 15 psi, use...