Bioscience Technology articles from October 2004

Bioscience Technology archives from October 2004

Microarray scanner.
October 1, 2004... LS Reloaded microarray scanners support customized array formats and microplates. High throughput and automatic gain control are accomplished using laser and filter combinations. Dynamic range of intensities is extended by providing a series of...

Protein Delivery Reagent.
October 1, 2004... Passport Protein Delivery Reagent facilitates non-cytotoxic delivery of biologically active cargo molecules, such as proteins, peptides or small molecules, directly into living cells. The newly discovered peptide translocates itself and...

Slide, array processing instrument.
October 1, 2004... Discovery XT automates immunohistochemistry (IHC), in situ hybridization (ISH), tissue microarray (TMA), and DNA microarray slide preparation and processing. Slide preparation steps, including baking, deparaffinization, cell conditioning, and...

Digital imaging for electrophoresis and blotting.(Editor's Choice)
October 1, 2004... KODAK Gel Logic 440 Imaging System features a cooled CCD camera and integrated illumination sample cabinet to permit sensitive detection of UV/fluorescent, chromogenic and luminescent samples in gel, membrane or plate assay formats. Cooled CCD...

Calibrate automated multichannel liquid handling systems.(Editor's Choice)
October 1, 2004... Multichannel Verification System MVS verifies and calibrates automated multichannel liquid delivery equipment. Based on ARTEL's patented Dual-Dye Ratiometric Photometry method, the MVS determines both the accuracy and precision of each...

RTPCR Master Mixes.(Editor's Choice)
October 1, 2004... RT-PCR Master Mix (2 x) and FideliTaq RT-PCR Master Mix (2 x) provide convenient, sensitive, specific, one-step RTPCR reactions in a single tube. These ready-to-use mixes are available with Taq DNA Polymerase, optimized tot routine detection,...

Arrayer accommodates plates, slides.(Editor's Choice)
October 1, 2004... Genetix hybrid bed option compliments its medium-throughput, fully featured QArray2 microarray platform. The bed can hold either a standard SBS dimension microplate or 2 standard slides within a single destination footprint, allowing the...

Class 1 and HEPA filtered enclosures.(Editor's Choice)
October 1, 2004... Purifier Class I Safety Enclosures provide user protection from agents that require Biosafety level 1, 2 or 3 containment and serve as an economical alternative to Class II biological safety cabinets when applications do not require product...

Fully automated research microscope.(Editor's Choice)
October 1, 2004... Leica DM6000 B fully automated research microscope incorporates Intelligent Automation, which keeps the instrument set for every imaging situation, based on personal, optimized settings. Switch between brightfield, phase contrast, DIC, or...

Utilizing automated classification of cellular responses to investigate apoptosis.(Tools & Techniques)
October 1, 2004... Introduction High content screening (HCS), or the automation of image-based cell biological investigation, has rapidly become a widely utilized approach in basic cell biological research and drug discovery. (1) Currently available tools...

On-line event focuses on biomarkers, expression profiling, RNAi.(New Products)
October 1, 2004... Keynote talks by Emmanuel Petricoin, MD, on The Potential for Clinical Applications of Proteomics and by Ruedi Aebersold, PhD, on Quantitative Proteomics: Now and in the Future will introduce the BioDiscovery Expo, a Web conference that will...

Shutter controller.(New Products)
October 1, 2004... SC-2000 two-channel shutter controller activates from a front panel switch, TTL signals, foot switches, or RS232 serial computer interface. In addition to simple on/off control, it provides programmable fixed shutter exposure time. When used...

Syringe-less filters.(New Products)
October 1, 2004... Whatman Mini-UniPrep Syringeless Filters remove particulates from samples being prepared for High Performance Liquid Chromatography (HPLC). The filters decrease sample batch processing time, and reduce the need for consumables, such as...

Electron multiplier CCD camera.(New Products)
October 1, 2004... The C9100 camera features high gain, and good signal to noise, resolution and speed combined with a proprietary hermetic vacuum chamber evacuated to [10.sup.-8] Torr. High vacuum, deep cooling and unit electronics reduce camera noise before the...

Label design software.(New Products)
October 1, 2004... LabelMark V3 software allows quick design and editing of labels. It supports most Windows printer drivers and is compatible with the TLS2200 and TLS PC Link portable printers, and accommodates all proprietary stock and custom formats. LabelMark...

Conductive Miniature Microfilter.(New Products)
October 1, 2004... Conductive Mini MicroFilters allows voltage to be applied through its stainless steel body, and is useful in applications such as mass spectrometry and CEC analysis. Like standard versions, it effectively filters along capillary flow paths with...

Lab monitoring system.(New Products)
October 1, 2004... eCENTRON combines several features in one lab monitoring system. Centron hardware, Web Access, internal CDRW drive, Autobackup software, four-hour battery backup, printer, monitor, keyboard, and mouse are all delivered in a tower chassis. The...

Variable, fixed volume and multichannel pipettors.(New Products)
October 1, 2004... Signature Pipettors are available in variable-volume, fixed-volume and multichannel models and offer accuracy and comfortable handle design. The pipettors cover the range from 0.2 to 5000 [micro]l in nine single channel units. They feature...

Ion trap mass spectrometer.(New Products)
October 1, 2004... LC/MSD Trap XCT Plus mass spec is offered for applications such as drug development and biomarker identification for disease research. New detector technology and improved manufacturing processes deliver a sensitivity specification of 250...

Microsphere and microarray stabilizers.(New Products)
October 1, 2004... StabilCoat Plus and StabilGuard Choice Stabilizers improve the stability of proteins bound to microspheres in solution, protect the activity of proteins while blocking nonspecific binding sites, and prevent aggregation, even after long-term...

Personal screening synthesizer.(New Products)
October 1, 2004... Advantage Series 2410 personal screening synthesizer helps process chemists who work with small amounts of material replicate the thermal and mixing conditions seen in larger production reactors. It provides efficient process development for...

Piezo-driven steering mirrors and scanners.(New Products)
October 1, 2004... Piezo-driven mirror scanners series now includes a device with an optical deflection range of 6 degrees. Piezo steering mirrors are driven by piezoceramic actuators providing acceleration to 10,000 g's, making them suitable for fast image...

Plant DNA isolation.(Genomics Focus)
October 1, 2004... UltraClean Plant DNA Isolation Kit isolates DNA from plant cells and tissues in less than 35 minutes. The kit removes polysaccharide and phenolic inhibitors of PCR yielding DNA greater than 50 kb in length. Purified DNA is ready for immediate...

Sequence analysis software.(Genomics Focus)
October 1, 2004... DNASIS MAX Version 2.5 Sequence Analysis Software tool delivers industry standard functionality--molecular biology tools, multiple consensus calling methods, and rapid BLAST searches--as well as features that enhance common task performance and...

PCR workstation.(Genomics Focus)
October 1, 2004... This workstation reduces DNA contamination in the chamber using high-intensity, shortwave 254-nm UV. Contamination control is provided with a coated stainless steel design that continuously maintains antimicrobial efficacy and resists growth of...

Frog array for environmental, developmental studies.(Genomics Focus)
October 1, 2004... MAGEX Frog cDNA Array is offered for research in developmental biology and environmental toxicology. The array is constructed using isolated gene fragments from Xenopus laevis and Rana catesbeiana frog species. It contains over 400...

RNA amplification system for gene expression analysis.(Genomics Focus)
October 1, 2004... The Ovation RNA Amplification System (NuGEN Technologies, Inc.), enables analysis of small samples for gene expression experiments, especially those based on real-time quantitative PCR (QPCR). Use of the system prior to QPCR analysis amplifies...

Clone sequence validation kit.(Genomics Focus)
October 1, 2004... SURVEYOR Check-It Kit (Transgenomic, Inc.) for clone sequence analyzes cloned DNA to detect mutations and errors that may have been inadvertently introduced into sequences during the PCR amplification and/or cloning processes, or to verify the...

Purify mRNA from cells, tissue, or total RNA.(Genomics Focus)
October 1, 2004... Qbiogene has introduced three ncw kits for purifying mRNA directly from cells, tissues, or total RNA. Formulated to achieve high yields, the kits incorporate a peptide nucleic acid (PNA) molecular probe that has an extremely high binding...

Custom and standard genotyping products.(Genomics Focus)
October 1, 2004... Affymetrix, Inc. and ParAllele BioScience offer early technology access to ParAllele's MegAllele genotyping reagents for use with Affymetrix GeneChip arrays, enabling researchers to perform large-scale gnotyping in their own labs with their own...

Microarrays screen for RNA interference.(Genomics Focus)
October 1, 2004... Microarray products offered by Genetix, Inc., are suitable for screening the efficacy of short-interfering RNA (siRNA) molecules in RNA Interference (RNAi) studies. Double-stranded siRNA molecules (typically 20-25 nucleotides in length) can be...

Centrifuge adapters for PCR plates.(Genomics Focus)
October 1, 2004... Eppendorf CombiSlide and PCR plate adapters provide maximum support during centrifugation in Eppendorf microplate rotors for multipurpose centrifuges 5804, 5804 R, 5810 and 5810 R. The CombiSlide glass slide/microarray adapter holds a maximum...

Plant leaf DNA extraction.(Genomics Focus)
October 1, 2004... Rapid Homogenization Kit, for extracting DNA from plant leaf tissue, enables quick and inexpensive processing of a sample yielding a solution containing DNA that is ready to be amplified using PCR. PCR compatible buffer system allows the use of...

Phagemid display system.(Genomics Focus)
October 1, 2004... pSKAN Phagemid Display System is offered for high-throughput screening of protein-protein interactions as well as for selection and production of novel proteins with specific binding properties and 3-D structure-based protein design. It can be...

Whole genome amplification service.(Genomics Focus)
October 1, 2004... MRC geneservice's (MRCg) Whole Genome Amplification service provides amplification of small quantities of DNA to provide sufficient quantities for larger scale and multiple projects. The service bolsters MRCg's range of genomic services, which...

Array-Ready Oligo set for Xenopus tropicalis genome.(Genomics Focus)
October 1, 2004... Array-Ready Oligo Set for the Xenopus tropicalis genome contains 10,898 70mer probes representing Xenopus transcripts, and provides a valuable tool for microarray analysis of Xenopus gene expression. Each probe is melting-temperature normalized...

Genotyping, AFLP analysis software.(Genomics Focus)
October 1, 2004... GeneMarker is an analytical tool for both AFLP and genotyping applications such as fragment and microsatellite analysis. The program features automated stutter peak and saturation correction, two of the most common genotyping difficulties....

Thermal melt analysis.(Genomics Focus)
October 1, 2004... Thermal Melt Analysis System, for use with proprietary UV-Vis spectrophotometers, monitors nucleic acid dissociation as temperature is raised, measures absorbance changes at user-specified wavelengths, and determines the melting temperature at...

High Throughput Oligonucleotides.(Genomics Focus)
October 1, 2004... High Throughput (HT)-Oligonucleotides are offered in 96 and 384 well-plates. Proven quality by mass spectra is offered for every oligo, along with short production times. The products will be of interest to those performing research on a large...

DNA extraction, purification.(Genomics Focus)
October 1, 2004... NucleoSpin Extract II Kit is suitable for both gel extraction as well as PCR purification. The procedure is simple. The spin column binds DNA to a silica membrane in the presence of chaotropic salt. Once the binding mixture is loaded directly...

Robotic centrifuge.(Automation/Robotics Focus)
October 1, 2004... Robotic version of Hettich's Rotanta 46RSC refrigerated centrifuge offers PC control and rotor positioning with maximum capacity of four, 750 ml round bottom containers, sixteen multiple-well plates or four deep-well plates. The 46RSC is...

Microplate Handling System.(Automation/Robotics Focus)
October 1, 2004... BenchCel Microplate Handling System (Velocity 11) automates a wide range of assays. It uses a high-speed shuttle to transfer microplates between integrated storage racks and two peripheral instruments. Compact footprint frees bench space, and...

Microwave-assisted synthesis integrates with robots, instruments.(Automation/Robotics Focus)
October 1, 2004... Nautilus integrated sample preparation system incorporates a microwave to enhance speed, reproducibility, and yield in synthesis. The Navigator is based on LISSY, CALLI, and LIPOS workbenches with a cutout on the right side for the microwave....

Plate stacker integrates with dispenser, washer.(Automation/Robotics Focus)
October 1, 2004... Thermo Electron Corporation has introduced the RapidStak microplate stacker for their Multidrop 384 Dispenser, Multidrop Micro Dispenser, and Wellwash AC Microplate Washer. Intuitive design allows the stacker to deliver and stack plates...

Lab Automation Software.(Automation/Robotics Focus)
October 1, 2004... Biomek Lab Automation Workstation Software Version 3.0 includes passwords, electronic signature, and customizable access and revision controls. The system administrator can set different permission levels for various functions, while a revision...

Automated plasmid DNA purification.(Automation/Robotics Focus)
October 1, 2004... BioRobot 3000 workstation and DirectPrep 96 BioRobot Kit together provide an automated package for performing plasmid minipreps in a 96-well format. The procedure enables reproducible purification of plasmid DNA that is ready for direct use in...

Cellular assay workstation with lidded plate handling.(Automation/Robotics Focus)
October 1, 2004... Quadra3 pipetting workstation is offered with lidded plate handling stackers and automatic de-lidding capability. The cellular assay station has interchangeable pipet heads, two standard bi-directional cassette stackers, and two Lidded Plate...

Compound storage.(Automation/Robotics Focus)
October 1, 2004... SmaRTStore small, automated compound storage unit provides storage for vials, plates and tubes at temperatures from ambient to -20 C. With a footprint of 2,000 mm W x 1,500 mm D x 2,400 mm H) it is capable of handling in the region of 260,000...

Microplate washer.(Automation/Robotics Focus)
October 1, 2004... Columbus Pro microplate washer is offered for applications ranging from diagnostic tests to cell based research. High wash performance derives from very low residual volumes (less than 2 [micro]l) and multiple aspiration points for each well....

Microplate centrifuge.(Automation/Robotics Focus)
October 1, 2004... VSpin Access microplate centrifuge system integrates with a range of automation platforms. It couples with a rapid plate shuttle to allow access by any robotic plate handler. Maximum speed is 3,000 rpm at 1,000 x g. Acceleration/deceleration...

Automated MALDI plate spotter.(Automation/Robotics Focus)
October 1, 2004... Accuspot MALDI plate spotter automates LC micro-fractionation, spotting and preparation for mass spec analysis. Used with any HPLC for proteome analysis, the system enables spotting in volumes of 10 nl or more on up to nine plates in 96 or...

Technology optimizes tube picking processes.(Automation/Robotics Focus)
October 1, 2004... TekCel, Inc.'s Adaptive Process Technology (APT) uses a combination of robotics and software to optimize tube-picking processes to achieve overall throughput and efficiency. APT runs from a laptop and requires lists of retrieval requests...

Automated dispenser.(Automation/Robotics Focus)
October 1, 2004... AutoDispenser Model AD 9602 incorporates an automated 12-channel, positive displacement syringe assembly that dispenses reagents into various 96-well plates. Exact plate positioning, X-axis motion control, and pneumatic positive syringe motion...

Microplate cytometer measures blue fluorescent protein reporter systems.(Automation/Robotics Focus)
October 1, 2004... Acumen Explorer 405 microplate cytometer is offered in a model with a single violet (405 nm) laser excitation source. The new version enables the [beta]-lactamase and blue fluorescent protein reporter systems which, until now, have routinely...

Chicken antibodies against neuronal/astrocytic markers.(Immunologicals Focus)
October 1, 2004... Chicken polyclonal antibodies against neuronal and astrocytic markers like GFAP, MAP2, NF-M, NF-H and Vimentin are available for double or triple immunostaining where rabbit or mouse antibodies are already in use. The image is of rat cortical...

T cell activation/expansion kit.(Immunologicals Focus)
October 1, 2004... Miltenyi Biotec kit provides activation and expansion of human T cells, by means of micron-sized Anti-Biotin MACSiBead particles. The T Cell Activation/Expansion Kit consists of Anti-Biotin MACSiBead particles and biotinylated antibodies...

cAMP assay development.(Immunologicals Focus)
October 1, 2004... HTRF cAMP homogeneous immunoassay is based on interaction between europium cryptate-labeled, anti-cAMP antibody and cAMP-XL665 conjugates. Two versions, cAMP femtomolar and cAMP dynamic, are both pre-packaged for either 1,000 or 20,000 tests on...

Immunoassay blocking solution.(Immunologicals Focus)
October 1, 2004... UltraBlock complex protein solution has been biotin reduced to undetectable levels by immunoassays with streptavidin-based detection methods. This formula provides blocking with low background to enhance the signal-to-noise ratio, and can be...

Recombinant mouse protein.(Immunologicals Focus)
October 1, 2004... Recombinant mouse Wnt-5a protein is a secreted glycoprotein with four potential N-linked glycosylation sites and a 10-amino acid Wnt-1 family signature sequence, CKCHGcSGSC. Mouse and human Wnt-5a share approximately 97% amino acid sequence...

DNA, RNA, protein quantitation assays.(Immunologicals Focus)
October 1, 2004... Four new kits are offered for the fluorescence-based quantitation of DNA, RNA, and protein in solution. Quant-iT assays provide results in minutes: dilute the dye with the buffer, add sample, and read fluorescence. Only 1-20 [micro]l of sample...

Orange fluorescent protein.(Immunologicals Focus)
October 1, 2004... CoralHue Kusabira Orange, a true orange fluorescent protein isolated from the stony coral Fungia concinna, absorbs light maximally at 548 nm and emits orange light at 561 nm. Wild-type CoralHue KO matures rapidly to form a fluorescent dimeric...

Small GTPase Activation Kits.(Immunologicals Focus)
October 1, 2004... EZ-Detect Small GTPase Activation Kits detect active or GTP-bound Cdc42, Rac 1, Rapl, Ras, and Rho from cell lysates. The kits utilize GST-fusion proteins immobilized on a resin to pull down active GTPases. Pulled-down, active GTPase is...

Polymerized reporter enzyme staining system.(Immunologicals Focus)
October 1, 2004... ImmPRESS polymerized reporter enzyme staining system is based on a new method of polymerizing enzymes and attaching these polymers to antibodies. Attaching an enzyme micro-polymer with a great density of active enzymes to a secondary antibody...

Antibody conjugation kit.(Immunologicals Focus)
October 1, 2004... This kit allows conjugation of antibodies to Qdot 655 nanocrystals. The kit contains the reagents and components for two conjugation reactions, each using 300 [micro]g of IgG class antibody, as well as a detailed protocol. The conjugation uses...

Human Bcl-2 EIA kit.(Immunologicals Focus)
October 1, 2004... Immunoassay are offered for quantitative determination of human total Bcl-2 in cell lysates. Bcl-2 (B-cell lymphoma 2) is an oncogenic protein that regulates cell death by controlling the permeability of the mitochondrial membrane. It inhibits...

Autoimmune related antibodies and antigens.(Immunologicals Focus)
October 1, 2004... BIODESIGN International has expanded its line of autoimmune related antibodies and antigens. Available products include antibodies to human thyroid peroxidase, human myeloperoxidase, U1 snRNP A/B, ribosomal P antigen, Jo-1 antigen, RNP antigen,...

Anti-Mullerian Hormone/Mullerian Inhibiting Substance ELISA.(Immunologicals Focus)
October 1, 2004... Anti-Mullerian Hormone/Mullerian Inhibiting Substance(AMH/MIS) ELISA is a mono/mono two-site test with a dynamic range of 0.05 10 ng/ml and sensitivity of 0.039 ng/ml. Featuring ready-to-use reagents and results in under 3 hours, the test may...

Prostaglandin E2 FPIA kit-red.(Immunologicals Focus)
October 1, 2004... Prostaglandin E2 (PGE2) Fluorescence Polarization Immunoassay (FPIA) facilitates high-throughput screening of PGE2 samples. This assay utilizes the red-shifted dye rhodamine as the label. It makes possible analysis of samples and increased rate...

ELISpot Kits.(Immunologicals Focus)
October 1, 2004... Protein Detector ELISpot Kits provide successful ELISpot assays with any matched pair of antibodies. The universal kits offer reproducible detection of protein-secreting cells. The enzyme-labeled streptavidin provided in the kit detects any...

Multiple Antigen Peptides.(Immunologicals Focus)
October 1, 2004... Multiple Antigen Peptides (MAPs) assist in immunization to raise antibodies, tools for immunization assays and therapeutics. Synthesizing MAPs enhances autigenicity (the ability to raise antibodies) of small peptides. MAPs serve as alternatives...

Serological pipette.(Labware Focus)
October 1, 2004... New 50 ml serological pipettes are gamma sterilized. They are manufactured from medical grade polyethylene and certified nonpyrogenic. Units are color-coded and cotton-plugged, with standard and negative printed graduations. Sarstedt Inc. ...

Culture flasks, vented caps.(Labware Focus)
October 1, 2004... Sterile polycarbonate flasks can be autoclaved. For shaker and suspension cell culture, they are compatible with cell culture media, reagents and buffers, and are virtually unbreakable. Triforest Enterprises, Inc. Use InfoLINK 4K1182 or...

Cell Culture Chamber.(Labware Focus)
October 1, 2004... 5-STACK CellSTACK Culture Chamber provides a cell growth area of 3180 [cm.sup.2] All 1-, 2-, 5-, 10-, and 40-STACK chambers are available with the CellBIND surface for cell attachment or standard tissue culture treatment. Customized filling and...

96-well filter plate.(Labware Focus)
October 1, 2004... MultiScreen Solubility Filter Plate, an automation-compatible, 96-well product for quantitative solubility assays, provides a filtration-based protocol validated to screen hundreds of samples per day. The plates conserve sample and provide...

Funnel for centrifuge slide prep.(Labware Focus)
October 1, 2004... Shandon EZ Megafunnel facilitates thin-layer slide preparations, and eliminates the need for metal Cytoclips. Intended for single use on the Shandon Cytospin cytocentrifuge, it is dedicated to preparation of samples of up to 6 ml. Strategically...

1536-well polypropylene deep-well plate.(Labware Focus)
October 1, 2004... Greiner Bio-One's 1536-Well MASTERBLOCK Deepwell meet SBS recommendations to ensure compatibility with automation and to be certified RNase/DNase-free and non-pyrogenic. Polypropylene is biologically inert, exhibits low binding characteristics,...

Plates for low-volume and optical assays.(Labware Focus)
October 1, 2004... Low-profile Multiplate 48-well unskirted microplates are offered for real-time, low-volume thermal cycling and other experiments. Compatible with most 96-well cyclers, the 91ates are available in clear, white (for enhanced fluorescent signal),...

Bar-coded cryogenic vials.(Labware Focus)
October 1, 2004... NALGENE 1.2, 2.0 and 5.0 ml standard and 1.5 ml SYSTEM 100 cryogenic vials with bar code are available for automated data collection, sample inventory or to mask the identity of samples. A code 128-numeric bar code is printed in black on a...

Disposable nanoliter pipette tips.(Labware Focus)
October 1, 2004... PocketTips disposable pipette tips deliver nanoliter amounts of molecular compound, and are compatible with existing liquid handling equipment. The U200 universal format tip dispenses 100 nanoliters of compound. Precision and accuracy are...

Bar-coded tubes.(Labware Focus)
October 1, 2004... Matrix Technologies had added to their line of 2D bar-coded storage products with the release of the ScrewTop TrakMates tube. The first 8 x 12 format screw tube and rack featurse a permanently attached, globally unique 2D barcode. Suitable for...

Sterile pipette tips.(Labware Focus)
October 1, 2004... BIO-CERT pipette tips and filtered pipette tips are offered for applications such PCR, DNA/RNA purification, sequencing, bioluminescence, ATP-detection, and others. The products are lot-tested for sterility and to be free of endotoxins....

Shallow 384-well plates.(Labware Focus)
October 1, 2004... NUNC 384 Shallow Well Plates combine the volume of a 1536 well plate with the technical benefits of a 384 well plate. Conical well shape (3.0/1.5 mm top/bottom diameters with flat bottoms) provides a working volume of 2 to 20 [micro]l, reducing...