Bioscience Technology articles from November 2006

Bioscience Technology archives from November 2006

Visualizing the biology of disease.
November 1, 2006... Quick, what do you think of when you hear the word "biomarkers?" For most people, the first thought is probably of markers of disease (or therapeutic response or toxicity) found in enzymes, proteins, hormones, and other substances detectable in...

Top biochemistry kits used by bioscience technology readers.(SNAPSHOT)
November 1, 2006... Top Biochemistry Kits Used by Bioscience Technology Readers Cell Assay Kits 31.7% Cloning 25.4% DNA Analysis/Purification 46% Immunoassay 46% PCR Research ...

Election results and science.(Editor's Note)(law for stem cell research)
November 1, 2006... I wonder if the results of the recent election will in turn mean more resources for scientists in the United States, or if there will be more support for scientific efforts. A shift in party dominance in the legislature does nothing to change...

MIT reveals inner lives of red blood cells.(Research News)
November 1, 2006... Using a technique known as quantitative phase imaging, researchers at MIT's George R. Harrison Spectroscopy Laboratory are able to see cell membrane vibrations as tiny as a few tens of nanometers. Studying cell membrane dynamics can help...

TOPAZ system instrumental in solving Asf1 structure.(Research News)
November 1, 2006... The TOPAZ system (Fluidigm Corp., South San Francisco, CA) has played a major role in the structure determination of Anti-Silencing Function 1 (Asf1) with histones H3/H4. Asf1, a highly conserved chaperone of histones H3/H4, assembles or...

Human cord blood stem cell differentiates into lung cell.(Research News)
November 1, 2006... A report published in Vol. 8, Issie 5 of Cytotherapy confirms the BioE Inc. (St. Paul, MN) Multi-Lineage Progenitor Cell (MLPC) is the first human cord blood stem cell to differentiate into a type II alveolar lung cell. Type II alveolar...

Biochip helps study living cells.(Research News)
November 1, 2006... Purdue University researchers have developed a biochip that measures the electrical activities of cells. In the near term, the chip could speed scientific research and accelerate drug development. Instead of doing one experiment per day,...

Laboratory automation system.(November's Innovations)
November 1, 2006... The Element lab automation system (from Velocity 11) facilitates mid-size applications (it is sized between the company's BenchCel Microplate Handling System and the larger BioCel Automation System). A compact floor-standing unit, the Element...

Microcapillary flow cytometry.(November's Innovations)
November 1, 2006... The Guava EasyCyte Plus microcapillary flow cytometry system is a compact high throughput system that provides absolute cell counts, 6 parameters (4 fluorescent colors, 2 light scatter), and a blue laser for access to commonly used fluorescent...

Integrated electrophysiological workstation for neuroscience applications.(November's Innovations)
November 1, 2006... The Nikon FN1 Multipatch upright focusing nosepiece microscope advantage of the properties of the "One Lens Solution" CFI75 16x water dipping objective. The objective has a 2.0 mm field of view, a numerical aperture of 0.80, a working distance...

Multiplexing platform.(November's Innovations)
November 1, 2006... The Comprehensive Solution (CS) Autoplex Gene Expression Platform and the Spectral Genomics Array Comparative Genomic Hybridization (CGH) Platform provide tools for improving gene expression validation, molecular karyotyping and genome...

Multi-channel pipettors.(November's Innovations)
November 1, 2006... Excel Electronic Pipettors are available in single channel, 8-channel and 12-channel versions. In addition to standard pipetting mode (for pipetting single volumes), the pipettors can be set for repeat pipetting, sequential pipetting, automatic...

Rotary evaporators.(November's Innovations)
November 1, 2006... Heidolph rotary evaporator Model 4003 control with motor lift features an integrated vacuum controller and vapor temperature controller with choice of three programs for automated distillations. It also allows for the setting of the nine most...

Centrifugal cell separation.(November's Innovations)
November 1, 2006... SpinSep separation method for human and mouse cells requires only a centrifuge, permitting multiple simultaneous separations, and is suitable for any sample, including frozen samples. Cells can be isolated from samples containing as few as...

Fluorescence illumination system.(November's Innovations)
November 1, 2006... Lumen 200 Series fluorescence systems specifically illuminate fluorescently labeled specimens using a 200 Watt metal arc lamp with a 2000 hour life span. The light is coupled to the microscope via a two or optional three meter liquid light...

Protein Purification Kits.(Proteomics Focus)
November 1, 2006... ProPur Kits provide total protein purification from initial fractionation to final polishing steps in yields typically associated with a gravity drip column, but with the speed of a spin column. IgG, IgA and Histagged proteins can be purified...

Protein expression system.(Proteomics Focus)
November 1, 2006... FreeStyle MAX System protein production technology has been developed for rapid, large-scale generation of post-translationally modified, functional proteins in Chinese Hamster Ovary (CHO) and HEK-293 suspension cell cultures. The large-scale...

Protein expression kit.(Proteomics Focus)
November 1, 2006... The K. lactis Protein Expression Kit provides a simple method for cloning and expressing genes of interest in the yeast Kluveromyces lactis. This system offers rapid high cell density growth, access to protein folding and glycosylation...

Protein microarray for antibody characterization.(Proteomics Focus)
November 1, 2006... Scientists involved in antibody development need to compare and validate many candidates. UNIchip protein biochips save time on downstream assays by enabling early selection of the best antibodies for validation. These protein microarrays...

Improving cryopreservation outcome.(Application Note)
November 1, 2006... Introduction Traditional cryopreservation can result in a 50 to 70% cell loss--a problem that is not often appreciated and often erroneously perceived as not critical to cell system quality. (1) A loss of this magnitude of stem or...

CHO cell media.(Product News)
November 1, 2006... GIBCO CD OptiCHO serum-free solution is optimized to support the growth of Chinese hamster ovary (CHO) cells and maximize protein expression from these cells. The chemically defined, protein-free formulation contains no hydrolysates, which...

ULS Labeling for CombiMatrix microarrays.(Product News)
November 1, 2006... ULS Labeling Kits provide specific formulations to CombiMatrix platform customers. Available formats include two color formats with Cy3 and Cy5, one color formats with either Cy3 or Cy5 and also kits with biotin ULS with the option of...

Screening service.(Product News)
November 1, 2006... GPCRProfiler service provides selective screening and characterization of lead compounds and screening of focused GPCR libraries. Accurate characterization of lead compounds provides comprehensive functional data, which accelerates optimization...

CGMP, PGE2, cortisol assays.(Product News)
November 1, 2006... Assays for cGMP, PGE2 and cortisol integrate a d2 acceptor dye. The cGMP (Cyclic Guanosine 3', 5'-cyclic monophosphate) assay addresses the needs of screening targets such as guanylyl cyclases or a number of cGMP-regulated phosphodiesterases...

Transfection of sensitive cells.(Product News)
November 1, 2006... PromoFectin provides reliable delivery of nucleic acids into a variety of cell types, including many hard-to-transfect cell lines and primary cells. It consists of a robust, non-liposomal polymer that is stable, water-soluble and free of any...

Rat whole genome expression chip.(Product News)
November 1, 2006... Illumina, Inc. offers a whole-genome expression product for rat that analyzes twelve samples in parallel on a single company BeadChip. Content for the new RatRef-12 Expression BeadChip is derived from the NCBI RefSeq database (Release 16), with...

Spin column digests proteins.(Product News)
November 1, 2006... Proteomics Grade Trypsin Spin Column reduces the amount of time required to digest complex protein mixtures to only 15 minutes. The column contains purified, TPCK-treated porcine trypsin, immobilized on a chemically modified silica support to...

Mycoplasma detection, elimination.(Product News)
November 1, 2006... Mycoplasma safety tools detect and eliminate various mycoplasma species in cell culture. The line includes specific detection kits based on conventional or real-time PCR as well antibiotic and non-antibiotic reagents for elimination of...

Two-plate immunoassay system.(Plate Reader Focus)
November 1, 2006... DS2 automated two-plate immunoassay system provides full automation in a small footprint instrument. The system quickly and easily processes two 96-well microplates and up to 12 different assays simultaneously and features a user-friendly...

Multi-mode microplate reader.(Plate Reader Focus)
November 1, 2006... Synergy 2 Multi-Detection Microplate Reader is a compact, modular system that provides fluorescence intensity, fluorescence polarization, time-resolved fluorescence, luminescence and UV-visible absorbance detection. The instrument combines a...

Benchtop spectrofluorometer.(Plate Reader Focus)
November 1, 2006... FluoroMax-4 offers sensitivity of at least 400,000 cps for the water-Raman peak at 397 nm, and a signal-to-noise ratio of 3000:1 minimum. Fluorescence measurements are facilitated by accessories and FluorEssence software for Windows. An...

Microplate handling system.(Plate Reader Focus)
November 1, 2006... StakMax integrated microplate handling system for the SpectraMax line of microplate, readers (Molecular Devices Corp.) enables researchers to run batches of microplates, which increases productivity and requires less hands-on time from...

In vivo experimental imaging of spinal cord injury: new platform and optics allow low-trauma imaging deep within organisms.(Application Note)
November 1, 2006... The ability to stimulate accurate axon re-growth is the ultimate goal in spinal cord injury research, but another key area of study comes from the fact that patients who have suffered such injuries are also at risk for potentially fatal...

NMR spectrometer.(Product News)
November 1, 2006... Avance II spectrometer's a 850 MHz US2 NMR magnet combines Ultra-Stabilized and UltraShield technologies to provide the benefits of active-shielded technology in a small footprint. Increased sensitivity and resolution allow the advanced studies...

Multi-sample whole-genome Genotyping BeadChips.(Product News)
November 1, 2006... HumanHap300-Duo and Duo+ Genotyping BeadChips enable simultaneous analysis of two samples, with more than 634,000 total tag SNPs on a single chip (317,000 tag SNPs per sample). The multi-sample format makes these products useful for loss of...

Automated crystallization.(Product News)
November 1, 2006... Compact Rhombix TableStore integrates storage and imaging in crystallization processes. The unit holds up to 176 standard 96-well SBS-format plates in an ambient storage unit. Clear, single- or multi-mode brightfield, darkfield or polarized...

Sample tracking software.(Product News)
November 1, 2006... Labtronics is pleased to announce the release of NEXXIS Sample Tracker (ST) version 3.0. The product provides small to medium sized labs with an affordable system for storing and tracking test results. With the latest release, authorized users...

MS post acquisition software.(Product News)
November 1, 2006... MassWorks post acquisition software package utilizes MSIntegrity technology to improve mass spectral measurements. It standardizes peak shapes, improves signal-to-noise, deconvolutes overlapped peaks, improves quantitative accuracy and...

Kinase profiling system.(Product News)
November 1, 2006... Desktop Profiler rapidly profiles compounds against a diverse kinase panel. It works in conjunction with ProfilerProT kinase panel kits. ProfilerPro microplates are preloaded with kinases, substrates and reagents, eliminating assay development...

Biomolecular interactions analysis system.(Product News)
November 1, 2006... Based on Resonant Acoustic Profiling (RAP) technology, RAPuid 4 enables real-time label-free measurement and analysis of biomolecular interactions. The flow-based system reduces the need to purify samples and generates accurate kinetic,...

Spectral Genomics Array CGH Platform.(Product News)
November 1, 2006... The Spectral Genomics Array CGH Platform offers a Bacterial Artificial Chromosome (BAC) based integrated solution consisting of the SpectralChip 2600 array, the Constitutional Chip 3.0 array, the ScanArray System, labeling reagents and...

Gene expression sample prep software module.(Product News)
November 1, 2006... Biomek 3000 GeXP Methods automates gene expression sample preparation. The software plug-in provides methods to prepare samples for the Beckman Instruments GenomeLab GeXP Genetic Analysis system on the Biomek 3000 Liquid Handling Workstation....

High throughput homogenizing.(Product News)
November 1, 2006... Programmable Omni Prep homogenizes up to 250 samples per hour. Operation with disposable Omni Tip probes eliminates cross contamination and cleaning. Brushless motor technology provides quiet operation and long motor life. Features include a...

Pipette Calibration System.(Product News)
November 1, 2006... PCSplus Pipette Calibration System has been upgraded with automation capabilities. The system reduces human transcription error and speeds calibration using software, a barcode scanner and a lab-qualified printer. Affixing barcode labels with...

Fluorescence imaging.(Product News)
November 1, 2006... The Leica AF6000 fluorescence imaging system combines the acquisition features of Leica's FW4000 fluorescent imaging systems with Leica Application Suite software. Image documentation, quantification, enhancement and analysis solutions evolve...

Imaging software sharing feature.(Product News)
November 1, 2006... NetCam, a feature of Olympus America's MicroSuite FIVE imaging software, allows the microscope user to share images easily with colleagues or students in other locations. Designed for use with Olympus's DP71, DP70, and DP20 and many other...

ChIP-on-chip prokaryote arrays.(Product News)
November 1, 2006... ChIP-on-chip microarray family includes four prokaryote species: Escherichia coli 0157, Salmonella typhimurium LT2, Salmonella typhimurium SL1344 and Streptomyces coelicolor. Chip2 microarrays can be used to identify the binding positions of...

Sample compartment microscope for FTIR.(Product News)
November 1, 2006... Irtron[mu] sample compartment microscopy system installs into the spectrometer sample compartment of JASCO FT/IR-4000 and 6000 Series FT-IR instruments in seconds without optical alignment. The unit can be operated using an integrated touch...

AFM employs new imaging mode.(Product News)
November 1, 2006... Asylum Research offers a new imaging mode, Dual AC, which is available on the company's MFP-3D Atomic Force Microscope (AFM). In Dual AC, the cantilever is driven at or near two or more of its resonance frequencies. Cantilever motion is then...

A novel protein design tool: protein crystallography labs are starting to reduce the amount of gene cloning they perform and shortcut the molecular biology process by designing optimized proteins from scratch employing de novo gene synthesis methods.(Application Note)
November 1, 2006... Introduction Welcome to the era of synthetic biology! Protein crystallography laboratories are starting to reduce the amount of gene cloning they perform and shortcut the molecular biology process by designing optimized proteins from...

Infrared Neural Stimulator.(Physiological Research Focus)
November 1, 2006... Renoir R-1850 Infrared Neural Stimulator (INS) is a fiber-coupled laser that generates reliable, pulsed, mid-infrared (IR) light. The compact, low-cost, optical neural stimulator exhibits excellent performance to the electrical stimulators...

Animal containment workstations.(Physiological Research Focus)
November 1, 2006... Three workstations with ULPA filtration are designed to protect animals, lab workers and the environment from particulate byproducts of feeding, cage changing and research protocols. Models include a mobile 4' Dual Access workstation, a 4' and...

Mouse genotyping service.(Physiological Research Focus)
November 1, 2006... Researchers in North America and Europe are offered transgenic, knock-out and knock-in mutant mice. TransnetYX's proprietary technologies for automated genetic testing and Internet biopsy submission and results reporting speeds the process,...

Rat Dual Energy X-ray Absorptiometry.(Physiological Research Focus)
November 1, 2006... Dual Energy X-ray Absorptiometry (DEXA) scan capabilities now include rat models. The DEXA Scan measures body composition, bone mineral content, bone area, bone mineral density (BMD), percent body fat, and percent lean tissue. It uses X-ray...

Comparative investigations on the blocking efficiency of filter pipet tips.(USA Scientific Inc.)
November 1, 2006... Introduction The blocking efficiency of filter tips is investigated using airborne particles. Filter tips seated on air displacement pipettors are used to prevent potential contamination of the pipettor tip cones (i.e. DNA fragments). The...

Multilayer tubing.(Product News)
November 1, 2006... This 78A durometer hybrid tubing combines the attributes of non-reactive polyethylene with clear, flexible medical grade PVC. The pure LDPE inner layer is compatible for contact with many reagents. The exterior non-DEHP PVC layer provides easy...

Multichannel liquid handler verification system.(Product News)
November 1, 2006... Capable of rapid volume verification of multichannel and automated liquid handlers, the MVS (Multichannel Verification System) produces traceable accuracy and precision measurements in one simple experiment. The system verifies liquid handlers...

Shaker line.(Product News)
November 1, 2006... Lab Companion laboratory shakers available in a number of sizes and temperature ranges in bench-top and floor model designs. Unit features include dual motion (orbital and reciprocal) control; programmable time, speed, and direction control...

Halogen illuminator.(Product News)
November 1, 2006... MI-150 Ring Light System, a 150-watt quartz halogen illuminator, includes a ring light that provides high intensity illumination at high magnifications and long working distances without light adjustment when refocusing or when zoom features...

Laminar Flow Clean Bench.(Product News)
November 1, 2006... Series 305 Horizontal Laminar Flow Clean Bench features a stainless steel table top with a white painted-steel shell, front access and interior lighting. Models are available for Class 100 or Class 10 environments. Bench length and height will...

Probe Colorimeter.(Product News)
November 1, 2006... Probe colorimeter Model PC950 measures transmittance, absorbance or concentration. It can be used manually or with any automation package; it can be customized for a specific application by selecting a fiber optic length and drop-in filter from...

Neuron transfection system.(Product News)
November 1, 2006... The HT Electroporation System with the ECM 830 square wave generator transfects cerebellar granule and hippocampal neurons. This electroporation method requires a small number of cells and easy-to-prepare reagents, and can be rapidly performed...

Blender for cell lysis.(Product News)
November 1, 2006... Bullet Blender gently and effectively breaks cell membranes or tissue samples. It provides timed control with 11 speeds of operation for different samples. At the highest speed, it is about as loud as a coffee grinder. Samples are completely...

Conductivity, temperature sensors.(Product News)
November 1, 2006... Single use, pre-calibrated sensors have stored ID, stored calibration data, stored lot number. The sensors feature tamper-resistant digital credentials and high and low alarms. They identify themselves and dump Real-Time documentation/graphing...

Environmental chambers.(Product News)
November 1, 2006... EnviroMax Environmental Chambers can serve as a stability tight tolerance chambers for locations where ambient conditions fluctuate or when specifications that call for environmental conditions that may require varying set points with precise...

PCR cabinets and workstations.(Product News)
November 1, 2006... This line of PCR systems offers six models that bring together UV irradiation and antimicrobial stainless steel for a contamination-free environment with select models featuring a HEPA filter system. The models are configured into two sizes to...

Web-based compliance support program.(Environmental Health & Engineering, Inc.)(Brief article)
November 1, 2006... Knowledge-based "eH&E-LabSupport" enables companies to manage environmental health and safety (EH&S) compliance programs, involving federal, state, and local regulations, without a large staff. A complete outline of a comprehensive compliance...

Microscope objectives.(Product News)
November 1, 2006... CY series of UIS2 plan achromat microscope objectives have built-in neutral density filters for light balancing, so the user can switch from high to low magnification without adjusting the light source. This provides automatic homogeneous...

UV Cryostat, UVC disinfection.(Product News)
November 1, 2006... Leica CM1850 UV Cryostat features AgProtect antimicrobial silver (Ag) ion coating, which protects users by reducing exposure to airborne and surface pathogens. When sectioning fresh tissue specimens in a cryostat, operators can be exposed to...

UPLC injector.(Product News)
November 1, 2006... Cheminert C72 UPLC Injector features a stator coating that permits pressures up to 15,000 or 20,000 psi. The injectors use the same mounting system as the widely used Cheminert C2 series HPLC injectors. The optional microelectric actuator...

Sample tube screw-cap automation.(Product News)
November 1, 2006... ALTO-8 provides access to eight sample tubes at a time. The system reduces the possibility of operator repetitive strain injury in the workplace from the manual opening and closing of caps. Contamination is reduced both from the manual handling...

Laboratory hoods.(Product News)
November 1, 2006... Benchtop Protector PassThrough Laboratory Hoods can be operated from either side. Mounted in an island or peninsular configuration, the hoods offer unobstructed viewing from either side, and thus they can be used for conducting chemistry...

High speed homogenizer.(Product News)
November 1, 2006... Light-weight, high-torque homogenizers provide speeds variable up to 30,000 rpm. Sealed tube chamber assemblies ensure safe operation. The homogenizer cannot operate when the blade is exposed, thus preventing injury and exposure to aerosols....

Small blender.(Product News)
November 1, 2006... Seward Stomacher 80 MicroBiomaster blender processes 250 [micro]l to 80 ml samples. It offers continuous adjustment of paddle speed, pressure, and processing time on the door panel. This feature is particularly useful when processing tissue and...

Culture plate nourishes cells from both sides.(Product News)
November 1, 2006... Optimized to grow and sustain high integrity cell monolayers, 96-well Millicell plate membranes nourish ceils from both the apical and basolateral sides. The plates are offered for analysis and cell growth, and can be used manually or with...

Micro polypropylene vials.(Product News)
November 1, 2006... Micro-Polyvials have been developed for storage and packaging low volumes of reagents. They are made of high purity, virginal polypropylene. Closure ensures tight sealing without the use of septa or liners. Slight conically shaped bottoms...

Large volume vacuum desiccator.(Product News)
November 1, 2006... Large quantities of standards, samples or other high value items can be safeguarded in the 65 liter (4000 cu/in) Secador Techni-Dome Vacuum Desiccator). The unit offers space for items up to 45 cm tall or wide including racks, trays and...

New light on neuronal networks.(Best Practices)
November 1, 2006... In neurobiology, crucial mechanisms work at various scales, ranging from molecular interactions between two cells to information traveling through networks of neurons. Using a variety of imaging techniques, scientists can probe the molecular...