Bioscience Technology articles from November 2005

Bioscience Technology archives from November 2005

Biomarkers all over.(EDITOR'S Note)(Editorial)
November 1, 2005... Writing for this issue of BioScience Technology, Contributing Editor Angelo DePalma titled his article. "Biomarkers: Biologists Best Friends." It's no wonder: they are ubiquitous, finding application at every level of biology, from basic...

MS-based biomarker research.(EDITOR'S Choice: NOVEMBER'S TECHNOLOGY)
November 1, 2005... BIOiTRAQ MS-based systems are offered for key phases of biomarker research. Workflows provide discovery, identification and quantitation within a single experiment. Systems suit varying research needs and budgets, incorporating iTRAQ and ICAT...

Phosphatase and tensin homolog activity assay.(EDITOR'S Choice: NOVEMBER'S TECHNOLOGY)
November 1, 2005... PTEN (phosphatase and tensin homolog) activity assay is offered in a non-radioactive 96-well ELISA format that directly measures PTEN activity in vitro, and that specifically measures the lipid product of PTEN. The assay has low interference,...

Refrigerators, freezers.(EDITOR'S Choice: NOVEMBER'S TECHNOLOGY)
November 1, 2005... SR-Series refrigerators and freezers are offered in both 23 cu/ft (single door) and 49 cu/ft (double door) models with stainless steel interior and exterior surfaces, microprocessor controls and digital temperature displays, available with...

Strep Tag system.(EDITOR'S Choice: NOVEMBER'S TECHNOLOGY)
November 1, 2005... Strep Tag technology is based on the strong and specific interaction between biotin and streptavidin. The short Strep Tag II fusion tag (8 amino acids) reduces potential interference with target protein structure or function. Strep Tag II binds...

Protein Stabilizing Cocktail.(EDITOR'S Choice: NOVEMBER'S TECHNOLOGY)
November 1, 2005... Protein Stabilizing Cocktail increases the shelf life of purified or partially purified proteins during routine storage. The formulation of low molecular weight, naturally occurring molecules helps protect proteins from environmental stresses...

Recombinant mouse Tryptase.(EDITOR'S Choice: NOVEMBER'S TECHNOLOGY)
November 1, 2005... Recombinant mouse Tryptase-5/Prss32 is encoded by the Prss32 gene. The mT5/Prss32 is a member of the mouse serine protease superfamily and is composed of a signal peptide, a pro region, a catalytic domain and a C-terminal hydrophobic peptide....

Methods development system maximizes electroporation yields.(EDITOR'S Choice: NOVEMBER'S TECHNOLOGY)
November 1, 2005... High throughput system maximizes electroporation yields of mammalian, bacterial and yeast cell lines. Suited for the delivery of siRNA and DNA expression vectors into mammalian cells, the system provides a 96-well electroporation plate and a...

Kits measure eight phosphoproteins.(EDITOR'S Choice: NOVEMBER'S TECHNOLOGY)
November 1, 2005... The Mercator PhosphoArray glass slide microarray measures phosphorylation of EGFR, FAK, Src, Paxillin, AKT, p38, HSP27 and ATF2. Made from a technology similar to sandwich ELISAs, the kits reproducibly quantify eight phosphoproteins with...

Cellular screening solutions.(EDITOR'S Choice: NOVEMBER'S TECHNOLOGY)
November 1, 2005... PerkinElmer Corp. offers a group of products dedicated to cellular screening. The LumiLux uHTS system enables luminescent ultra-high throughput cellular screening with all types of cells in 1536 well format. The LANCE cAMP assay features a...

Biomarkers: biologists' best friends.(Cover Story)
November 1, 2005... Biomarkers have become the workhorses of basic research, drug discovery, preclinical drug development, clinical testing, and at their most refined, human diagnostics. Under their broadest definition, biomarkers include any biological or...

Miniature, remote syringe pump and micro injector.(LIQUID HANDLING)
November 1, 2005... Nanomite micro injector pump features a small pump controller and a thin-profile remote pumping head. The device holds syringes up to 6-mm diameter, from 0.5 ml to 1.25 ml, and achieves the linear force needed for gas tight microsyringes....

Shaking water baths.(LIQUID HANDLING)
November 1, 2005... A universal spring tray is available for Julabo's SW22 and SW23 shaking water bathes. It allows for the insertion of almost any type, or combination, of beaker, flask or sample container. The SW22 features a simple-to-operate and clear, legible...

Water purification system.(LIQUID HANDLING)
November 1, 2005... EIix Clinical laboratory water purification system supports medium-sized clinical analyzers performing chemistry and immunochemistry assays. Water quality significantly impacts the precision and sensitivity of laboratory test results. According...

Fully autoclavable pipettes.(LIQUID HANDLING)
November 1, 2005... Labpette Discovery Pipettes provide accuracy, reproducibility, comfort and safety. Volume is easily set using either thumbwheel or pushbutton. Pushbutton design prevents accidental change. An ergonomic design and reduced plunger forces make the...

Linear encoder stage.(IMAGE ANALYSIS MICROSCOPY)
November 1, 2005... BioPrecision2 stage features embedded linear encoders with a resolution of 0.1 micron. The stage is suited for time lapse experiments, image tiling and measurement applications. The stage emphasizes ergonomics, performance and microscope...

High speed CCD camera system.(IMAGE ANALYSIS MICROSCOPY)
November 1, 2005... SPOT Pursuit XS digital camera system delivers 14-bit megapixel images up to 11 full frames per second at less than 8 electrons read noise. With Binning and ROI, the camera delivers over 130 frames per second and has been finely tuned for high...

Microscopy, image capture software.(IMAGE ANALYSIS MICROSCOPY)
November 1, 2005... PixeLINK Capture Standard Edition (SE) software, for use with microscopes and PixeLINK digital cameras, provides live preview of image data from the computer, full control of camera and image capture settings, and image calibration and...

Image dababase, analysis.(IMAGE ANALYSIS MICROSCOPY)
November 1, 2005... IQbase 2.0 enterprise image asset management software (Media Cybernetics) offers database enhancements and new display, measurement and collaboration tools that enable organizations to store, query, and share images and data. Analytical tools...

Genotyping system.(ARRAY TECHNOLOGIES)
November 1, 2005... The 48-plex GenomeLab SNPstream (Beckman Coulter, Inc.), an automated, multiplexed genotyping system, can process up to 48 SNPs in each well of an arrayed 384-well plate. Operation at consistent cost per genotype or per sample, regardless of...

Microarray Analysis System.(ARRAY TECHNOLOGIES)
November 1, 2005... The ScanArray [G.sub.x] PLUS Microarray Analysis System is a dedicated 2-laser, entry-level microarray scanner. Single slide scanning can be upgraded to high-throughput automated scanning and analysis with a 20-slide autoloader. Dual color...

Print arrays in plate wells.(ARRAY TECHNOLOGIES)
November 1, 2005... Genomic Solutions Inc. offers Plate Arraying technology on the BioRobotics MicroGrid II arraying instrument and the GeneMachines OmniGrid Accent microarrayer This option enables the production of DNA and protein microarrays in 96 and 384-well...

Human Protein Microarray.(ARRAY TECHNOLOGIES)
November 1, 2005... ProtoArray Human Protein Microarray version 3.0 enables screening of biological samples or of a labeled probe of interest against 5,000 unique human proteins in a single experiment. Full-length, native human proteins from a broad range of...

Histidine-tagged protein purification using recombinant DNA techniques.(APPLICATION Note)
November 1, 2005... The use of recombinant DNA techniques for protein expression and purification has increased greatly in recent years. The abundant amounts of recombinant proteins that can be produced in bacterial hosts gives rDNA (recombinant DNA) techniques an...

Nucleic Acid Stain Kit.(NEW Technology)
November 1, 2005... SilverSure Nucleic Acid Stain Kit provides results in under 30 minutes. The reagents detect either DNA or RNA in any type of agarose. Results are achieved without the need for chemical mutagens or UV transilluminators. Sensitivity levels are...

Rotational vacuum concentrator.(NEW Technology)
November 1, 2005... MAXI-concentrator type RVC 2-33 is suited for large sample volumes and all commonly used solvents. Typical applications include evaporation of multiple small samples within biology, microbiology, biochemistry, DNA/RNA (ethanol, methanol), PCR...

Small, two-glove position barrier isolator.(NEW Technology)
November 1, 2005... Small, two-glove position version of the SterilSHIELD barrier isolator (The Baker Co.) offers a contained, positive-pressure work area. Providing aseptic compounding of non-hazardous drugs in compliance with USE the SS500 model creates a...

ROX-Free DNA Polymerase Kit.(NEW Technology)
November 1, 2005... QTaq ROX-Free DNA Polymerase Kit, for real-time quantitative PCR (qPCR), allows individual adjustment of passive reference dye concentration. Because the ROX dye is provided separately, users can determine the best passive reference dye...

Transcription factor assay.(NEW Technology)
November 1, 2005... PPARa transcription factor assay offers a non-radioactive method for detecting PPARa binding activity in nuclear extracts. A 96-well enzyme-linked immunosorbent assay (ELISA) replaces the radioactive electrophoretic mobility shift assay (EMSA)....

Large scale DNA isolation from soil.(NEW Technology)
November 1, 2005... PowerMax Soil DNA kit isolates DNA from up to 10 g of almost any soil type. The DNA yields are high and clean, and total DNA is free from inhibitors that could affect RT PCR. Each ready-to-use kit includes all required reagents. The researcher...

Enzymes, biochemicals.(NEW Technology)
November 1, 2005... Enzymes, biochemicals and primary cell isolation kits are offered for application in life science research, diagnostics and biotechnology. New and traditional products in the line find application in cell culture, protein research, diagnostic...

Labels will not jam in autoclave.(NEW Technology)
November 1, 2005... Computer Imprintable Label Systems (CILS) offers a label that will prevent vials fusing together in autoclaves. The labels utilize a material/adhesive combination that maintains integrity during the sterilization process. CILS International,...

Insect-based protein expression system.(NEW technology)
November 1, 2005... Triple Express nonlytic insect-based protein expression system combines an expression cassette (engineered from the silk moth cytoplasmic actin A3 gene, a strong constitutive cellular promoter), an enhancer element and a transcriptional...

Dynamic Anesthesiometer.(NEW technology)(Brief Article)
November 1, 2005... Dynamic Von Frey Instrument (Plantar Anesthesiometer) assesses sensitivity to light touch and is used in quantifying analgesic effects, detecting nerve sensitivity and neuropathy. A tiny filament lightly touches the plantar surface, and gentle...

Heat-Labile Alkaline Phosphatase.(NEW technology)
November 1, 2005... APex Heat-Labile Alkaline Phosphatase uses a single protocol to dephosphorylate blunt, 5'-overhang and 5-recessed DNA ends, regardless of the length of the overhang. It functions over a range of pH, ionic strength and temperature conditions,...

Phosphatase inhibitor.(NEW technology)
November 1, 2005... Halt phosphatase inhibitor cocktail preserves phosphorylation of proteins in cell and tissue lysates, and contains four phosphatase inhibitors of broad specificity: sodium fluoride, sodium orthovanadate, sodium pyrophosphate and...

Chromatography magnetic beads.(NEW technology)
November 1, 2005... Dynabeads RPC 18 are based on reversed-phase chromatography (RPC) or weak cation exchange (WCX) chromatography and can fractionate mixed protein and peptide samples quickly and easily. Optimized surface binds intricate peptide mixtures....

Lab seating.(NEW technology)
November 1, 2005... VWR Contour adjustable-height chairs and stools provide comfort and support in a range of tasks. Three styles and two stool styles are available in desk, medium-bench and high-bench heights. Black vinyl upholstered chairs provide a greater...

Yeast two- and one-hybrid technology.(NEW technology)
November 1, 2005... Y2H Membrane Protein System allows two-hybrid screening for proteins interacting with full-length membrane-integrated or membrane-associated proteins. The system enables detection of membrane protein binding partners and identification of their...

Western and chemiluminescent substrates.(NEW technology)
November 1, 2005... Immobilon Western HRP and AP chemiluminescent substrates provide high signal response at mid-femtogram levels. Primarily used in Western and dot/slot/spot blotting applications, each substrate provides a high signal intensity to facilitate the...

Solid phase synthesis resin.(NEW technology)
November 1, 2005... Resin for solid phase synthesis of resin-bound unnatural amino acids, PL-BIG-W Resin is added to Polymer Laboratories' StratoSpheres line. The resins offer batch to batch reproducibility, optimized particle sizes and high loading capacity....

Nucleic acid purification.(NEW technology)
November 1, 2005... Nucleic acid purification and quantitation kits are optimized for front-end DNA or RNA process. Chemistries match applications with ChargeSwitch and GeneCatcher technologies, as well as traditional silica and anion exchange products. Invitrogen...

M2A antibody.(NEW technology)
November 1, 2005... Mouse monoclonal antibody, clone D2-40, specifically recognizes M2A Antigen, a 40-kD oncofetal antigen characterized as an O-linked sialoglycoprotein that is expressed on lymphatic endothelial cells in normal and tumor tissues. This antibody...

Microcentrifuges.(NEW technology)
November 1, 2005... Microcentrifuge models 5418 and 5424 include standard aerosol-tight rotors that hold 18 or 24 microcentrifuge tubes, respectively. Lids optimize airflow and reduce noise levels to background level. Operation is quiet, even for runs that do not...

Dynamic Light Scattering instrument.(NEW technology)
November 1, 2005... A recent application by IBMC-CNRS, Strasbourg, France, has demonstrated that Wyatt Technology's DynaPro Titan range of Dynamic Light Scattering instruments can be used to determine whether freezing alters a macromolecule's homogeneity or not....

HPLC silica media.(NEW technology)
November 1, 2005... The Gemini C18 HPLC column achieves extended pH 1-12 stability with silica performance by using a silica manufacturing process. The extreme pH ruggedness permits method developers to perform cyclic pH testing for rapid method development. The...

Columns for Eksigent HPLC.(NEW technology)
November 1, 2005... ChromXP columns for the Eksigent Technologies ExpressLC HPLC operate at high linear flow velocities. The columns are offered with C18 material in 3m m and 5m m particle sizes in lengths from 3 cm to 15 cm, with other chemistries to follow....

Personnel consultants.(LITERATURE FOCUS)(Advertisement)
November 1, 2005... FPC is a national network of executive search firms. The company has been providing human resource solutions since 1959. Advocates for both companies and candidates, FPC recruiters are committed to bringing together the right candidate with the...

Laboratory Chemicals.(LITERATURE FOCUS)(Wako BioProducts )(Brief Article)
November 1, 2005... Wako BioProducts has changed its name to Wako Laboratory Chemicals to incorporate all the reagents that we can supply. There are over 15,000 reagents in our new catalog! We are constantly adding new and unique items to our product lines to keep...

New -190 C freezer.(CBS ISOTHERMAL )(Brief Article)
November 1, 2005... CBS ISOTHERMAL liquid nitrogen vapor phase storage systems allow frozen sample storage at liquid nitrogen temperatures without liquid nitrogen contact. This innovative design provides storage temperatures in the -190 C range with absolutely no...

BioDiscovery Online Conference & expo.(LITERATURE FOCUS)(Advertisement)
November 1, 2005... Archive Online Event. The BioDiscovery Online Conference program features a speaker roster that includes numerous senior level scientists from leading universities and top pharmaceutical and biotech companies. The conference is comprised of...