Bioscience Technology articles from May 2006

Bioscience Technology archives from May 2006

What is cancer research worth?(Editor's Note)
May 1, 2006... A press conference held during the American Association for Cancer Research annual meeting last month addressed the reduction in federal spending for cancer research for budget year 2006, and a likely further reduction in spending for 2007....

Stereomicroscope, transmitted light bases.(May's Innovations)
May 1, 2006... This line of stereomicroscopes with transmitted light bases provides illumination for a variety of applications. The all-purpose TL ST base incorporates a halogen illumination system that provides brighfield or pseudo-darkfield transmitted...

Kinase screening kit.(May's Innovations)
May 1, 2006... The HTRF KinEASE kinase assay development kit allows profiling and high-throughput screening of a large range of Ser/Thr kinases, major targets in drug discovery. The kit combines antibody and kinase substrates with homogeneous time resolved...

Automated proteomics workstation.(May's Innovations)
May 1, 2006... ProLink Express automated proteomics work-cell integrates all plate delivery and transfer operations with automated data tracking from initial bacterial colony picking through final protein expression and measurement. The system links all the...

Water purification system.(May's Innovations)
May 1, 2006... The Milli-QAdvantage converts pure water to ultrapure water. Rather than purchasing separate production units, several final point-of-use polishers are available to match the required application. The production units can be placed on the...

Nanoliter dispensing system.(May's Innovations)
May 1, 2006... Single channel, non-contact nanoliter dispense system is available for the Hydra II line of automated pipettors. When coupled with the 96 or 384 channel positive displacement pipetting capabilities of the Hydra II, the single channel eDrop...

In vitro imaging system.(May's Innovations)
May 1, 2006... LI-COR Biosciences has introduced a new accessory and IRDye reagents for in vivo molecular imaging on its Odyssey Infrared Imaging System. The Odyssey MousePOD Imaging Accessory fits over the standard Odyssey scanning surface for in vivo...

SNP multiplexing kit.(May's Innovations)
May 1, 2006... Based on single-based primer extension technology, the GenomeLab SNPStart primer extension kit is validated and optimized for multiplexing up to 10 SNPs in a single tube. Ideal for low- to medium-throughput applications, this kit provides a...

Assay system.(May's Innovations)
May 1, 2006... GreenScreen GC eukaryotic genotoxicity assay rapidly screens lead compounds. The assay system is designed for use early in drug discovery. In a recent study, 2698 proprietary compounds were tested, as well as 51 marketed pharmaceuticals. The...

Gene expression: better tools: more complex results.(Cover story)
May 1, 2006... Gene expression has become a mainstream technique in biology, medicine, and drug development. Broadly speaking, gene expression comes in two flavors: analytical and functional. The former refers to detecting and quantifying genes, especially by...

Micro HPLC system.(HLPC Focus)
May 1, 2006... UltiMate 3000 Series chromatography systems (Dionex Corp.) feature a comprehensive range of modules, including five micro pump systems optimized for flow rates of 10 [micro]l/min to several ml/min. Fast separations are provided on 1-3 mm ID...

Liquid chromatography system.(HLPC Focus)
May 1, 2006... The 1200 Series HPLC system (Agilent Technologies Inc.), a high-throughput configuration of the company's 1100 Rapid Resolution system, allows sequential execution of more than 2,000 samples per day without compromising data quality or method...

UPLC/MS system.(HLPC Focus)
May 1, 2006... The ACQUITY SQD Ultra Performance Liquid Chromatography/Mass Spectrometry (UPLC/MS) features the Waters SQbenchtop, single-quadrupole, atmospheric pressure ionization (API) mass detector for routine UPLC/MS analyses. IntelliStart Diagnostic...

2-dimensional HPLC series.(HLPC Focus)
May 1, 2006... HPLC series includes the 2D Micro-HPLC System for Proteome Analysis, the 2D HPLC for Bioanalysis (BA), and the 2D HPLC for NMR Sample Preparation. The systems incorporate Shim-pack MAYI Restricted Access Media (RAM) pretreatment columns that...

Finding Factor II and V Leiden polymorphisms with gold nanoparticles.(Application Note)
May 1, 2006... Abstract The method is based on hybridization of the target by allele-specific surface-immobilized capture probes and gene-specific oligonucleotidefunctionalized gold nanoparticle probes, followed by a signal amplification process for...

Colony picker.(PRODUCTS: Instruments & Systems)
May 1, 2006... CP7200 picks colonies at rates of up to 7,200 per hour. Software allows shifting from plate-to-plate and even run-to-run without re-calibration. Instrument footprint is 22" x 20". It is reliable, and utilizes a continuous configuration that...

Clinical data repository.(PRODUCTS: Instruments & Systems)
May 1, 2006... Combining information from multiple sources, this repository provides integration and reporting for clinical and non-clinical data that enables regulatory compliance. All aspects of the integration process can be managed--data access,...

In-vitro imaging of protein biomarkers.(PRODUCTS: Instruments & Systems)
May 1, 2006... MALDI Molecular Imager facilitates in-vitro imaging of peptide and protein biomarker distributions in tissue sections and cell clusters. An autoFlex MALDI-TOF mass spectrometer equipped with smartbeam laser technology provides high-throughput...

Electronic pressure control module.(PRODUCTS: Instruments & Systems)
May 1, 2006... The VSO-EP is a module for precision control of critical system pressures. An automated alternative to manual pressure regulators, needle valves, flow controllers, and bleed orifices, it provides integral closed-loop proportional control for...

Multi-mode potentiostat.(PRODUCTS: Instruments & Systems)
May 1, 2006... BioStat multi-mode potentiostat is compatible with most electrochemical sensors or electrodes, and allows independent amperometric or potentiometric measurements on four electrically-isolated channels. The system handles signals of either...

Real-time PCR platform.(PRODUCTS: Instruments & Systems)
May 1, 2006... LightCycler 480 Real-Time PCR System (Roche Applied Science) is a multiwell plate-based platform for qualitative and quantitative detection of nucleic acids and genotyping. Interchangeable blocks are used for 96 or 384 samples. Building on...

Informatics system integrates molecular modeling.(PRODUCTS: Instruments & Systems)
May 1, 2006... MolSAR (Molecular Structure Activity Relationships) molecular modeling technology has been integrated into the KnowItAll Informatics System (Bio-Rad Laboratories, Informatics Group. MolSAR uses Bayesian neural network technology to build in...

HPLC detectors.(PRODUCTS: Instruments & Systems)
May 1, 2006... Surveyor Plus refractive index and fluorescence detectors enhance analytical capabilities when integrated with the Finnigan Surveyor Plus HPLC product line (Thermo Electron Corp.). The fluorescence detector monitors the emissions of...

Protein, peptide column.(PRODUCTS: Instruments & Systems)
May 1, 2006... ProPac HIC-10 separates proteins and peptides by hydrophobic interaction chromatography. The stationary phase consists of 5 gm, 300[Angstrom] pure spherical silica gel particles, which are functionalized with multi-dentate amide groups. Surface...

Sorbents, gels, cartridges.(PRODUCTS: Instruments & Systems)
May 1, 2006... This family of products for all phases of chromatography includes a selection of sorbents such as silica gels, bonded phases, aluminas, polymer resins and more. TLC plates, flash cartridges, HPLC columns and SPE cartridges are available. *...

Pathway analysis software.(PRODUCTS: Instruments & Systems)
May 1, 2006... PathwayStudio Version 4.0 contains new tools for microarray data analysis and pathway dynamics simulation, as well as over 1000 reconstructed pathways. It scales from desktop to enterprise-wide, and allows scientists to reconstruct pathways,...

Electrophoresis products.(PRODUCTS: Instruments & Systems)
May 1, 2006... Injection molded electrophoresis product includes horizontal and vertical gel electrophoresis units, blotting units, comet assay and cellulose acetate systems, IEF systems, power supplies, DNA sequencers and gel documentation systems for...

Re-packaged media products.(Cell Culture Focus)
May 1, 2006... GIBCO has re-designed their media bottle labels and caps, both of which are now color-coded by product family to make it easy to identify the cell culture products they contain. The labels utilize internationally recognized industry symbols for...

Human Neural Stem cell kit.(Cell Culture Focus)
May 1, 2006... Human Neural Stem Cell (NSC) Functional Identification Kit contains media supplements that can be used for the short-term maintenance, differentiation, and expansion of NSCs, and for their induction into astrocyte, neuron, and oligodendrocyte...

Mammary epithelial cell media.(Cell Culture Focus)
May 1, 2006... Reformulated EpiCult-B is an optimized medium for the culture and characterization of mammary cells without the addition of cholera-toxin. The serum-free product is specifically formulated for the growth of human and mouse mammary luminal and...

Fluorescent labels.(Cell Culture Focus)
May 1, 2006... Chromeo Dyes exhibit broad Stokes shifts, stability toward photobleaching and pH, and low cell toxicity, making them useful as labels of biomolecules in cell culture staining experiments. Currently, Chromeo Dyes are available as Chromeo...

Normal peripheral blood cells.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... PoieticsPTMP Leukopaks are bags of fresh human blood cells collected from normal peripheral blood by automated apheresis in ACD-A anticoagulant and density gradient centrifugation. Each Leukopak contains a mixture of monocytes, lymphocytes,...

Tissue disruption/ RNA purification.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... Multi-enzymatic liquefaction of tissue (MELT) RNA isolation system enables hands-free disruption of multiple solid tissues in parallel without homogenization or tissue grinding. Thus, there is no equipment to clean between samples. Up to 10 mg...

Membrane protein interactor screening system.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... With the DUALmembrane Screening System, full-length membrane integrated bait proteins are screened against cDNA library expressed prey proteins to identify interactions between potentially unidentified integral membrane and soluble proteins....

DNA polymerase.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... PrimeSTAR HS DNA polymerase provides high fidelity as well as an extended product length--8.5 kb for human genomic DNA and 22 kb for [lambda] DNA. It is suited for PCR cloning applications. Priming efficiency leads to amplification efficiency...

RNA/Protein Kit.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... AllPrep RNA/Protein Kit (Qiagen, Inc.) purifies total RNA and native protein simultaneously from the same sample of cultured cells. The purified RNA and protein provide high performance in downstream applications, such as Western blotting,...

Nitrite assay kit.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... Ready-to-use colorimetric nitrite assay detects phosphate concentrations from 2 [micro]m to 10 [micro]m and can be performed in cuvettes or microplates. Nitric Oxide is detected in biological fluids via nitrite. Additionally, nitrate can be...

Monoclonal, for cellular function analysis.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... IOTest CD85d-(ILT4)-PE conjugated monoclonal antibody is useful in basic research on leucocyte function, dendritic cells, immunosuppression, tolerogenicity and maternofetal tolerance. ILT4 is selectively expressed on myelomonocytic cells and...

Human cDNA Library Panel.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... Human SpliceMiner cDNA Library Panel simplifies the process of discovering rare and unique alternative splice forms. The panel consists of ~ 4.6 million primary cDNA clones derived from 15 cDNA plasmid libraries representing 28 cancer cell...

Kinase Assay.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... Transcreener KINASE Plus Assay is a far-red competitive fluorescence polarization immunoassay, optimized for enzymatic assays which generate ADP and require high concentrations of ATP (up to 250 [micro]M and above). Developed originally to...

Human, mouse, rat arrays.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... OpArrays, pre-printed microarrays for the human, mouse (Mus musculus), rat (Rattus novegicus), and Arabidopsis thaliana genomes, are part of a line that includes microarrays for all of the 40 + genomes currently offered through the ARmS (Array...

Comet Assay control cells.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... Stable control cell preparations contain known levels of DNA damage for use as standards when performing the CometAssay. When they are electrophoresed in the CometAssay, the controls consistently produce the same comets with predetermined tail...

Protein sample prep.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... Protea Explorer protein sample preparation instrument integrates the various steps of protein sample preparation, from a single gel-spot to the mass spectrometer. Processing time is a few hours. The enclosed system permits a large menu of...

High-content bio-imaging.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... This collection of monoclonal anti-body reagents has been tested and certified for utility in automated bio-imaging (high content) and microscopy applications. To be certified, each antibody must pass a number of tests that include exceeding a...

Peplides, for protein analysis.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... HeavyPeptides, isotopically-labeled, non-radioactive custom peptides offered for mass and NMR spectroscopy, can be used as sequence-identical internal weight standards for quantitation of proteins and protein mixtures. HeavyPeptide AQUA kits...

miRNA Isolation, Labeling Kit.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... The miRacULS miRNA Isolation and Labeling Kit combines the upstream isolation of small RNA from tissue or cultured cells and the reagents necessary to label these samples for DNA microarray analysis. The kit is available with the ULS labeling...

Acylcarnitine profiling assay.(PRODUCTS: Biochemicals & Kits)
May 1, 2006... Acylcarnitine profiling platform assists in drug discovery and development for a range of critical diseases and metabolic conditions. Acylcarnitines are intermediates in mitochondrial beta-oxidation, or fat burning. Their measurement in serum...

High throughput RNA quality control: the multi-channel, real-time, light-induced fluorescent detection capillary electrophoresis system provides a reliable method for routine RNA quality analysis.(Application Note)
May 1, 2006... Importance of RNA quality analysis Determining the integrity of RNA is an essential step before gene expression analysis, because RNA quality can have a tremendous effect on downstream microarray analysis, data interpretation of gene...

Hot plates, stirrers.(Sample Processing Focus)
May 1, 2006... Corning hot plates, stirrers and stirring hot plates provide precise temperature as measured in the liquid being heated (as opposed to the plate top) and stirring speeds accurate to +5%. Digital displays indicate when set temperature and...

Robotic centrifuge.(Sample Processing Focus)
May 1, 2006... Robotic version of the Rotanta 46RSC refrigerated centrifuge offers computer control and and maximum capacity of four, 750-ml round bottom containers, 16 microtiter plates, or four deep-well plates. Designed for automatic sample processing, it...

Swing-out rotor for microtubes.(Sample Processing Focus)
May 1, 2006... The C0230-HLA-RAis 12 position swingout rotor is suited for HLA applications or any protocol requiring separation of the pellet to the bottom of a microtube. Available for both the Hermle Z233-M2 and the refrigerated Z233-MK2, it can reach...

Multiple position microplate mixer.(Sample Processing Focus)
May 1, 2006... The MultiMicroPlate Genie, with capacity for up to four operates at Speeds from 750-3200 rpm. This combination of features ensures complete mixing in each microplate well, even in 384-well formats. Any type of skirted microplate with a standard...

Non-invasice micro injection.(Sample Processing Focus)
May 1, 2006... SLAM (Soft Lipid-Assisted Microinjection) pipette provides micro-injection capability without the need to impale or rupture a cell membrane. A lipid coating on the tip simply fuses with a cell membrane, allowing pipette contents to be...

Ventilator.(Sample Processing Focus)
May 1, 2006... MiniVent Ventilator is ideal for mice, but may also be used for peri-natal rats. Respiration rate is adjustable from 60 to 400 strokes per minute and tidal volume is adjustable from 30 to 350 microliters. The palm-sized unit takes up little...

Pre-saturated, sterile wipers.(Sample Processing Focus)
May 1, 2006... A complete line of dry, pre-saturated and sterile KIMTECH PURE Wipers is available for all cleanroom environments. CL3 wipers can be used in ISO Class 3 or higher cleanroom environments. The dry wipers are 100% continuous filament doubleknit...

Plastic cryogenic vials.(Sample Processing Focus)
May 1, 2006... Three styles of cryogenic vials are available: internal thread, external thread, and plug seal. The vials come in 1.2, 2.0, 4.0 and 5.0 ml sizes. All vials are manufactured from polypropylene for use at temperatures to -196 C, have a one-turn...

Stainless steel LC fittings.(Sample Processing Focus)
May 1, 2006... This line of two-piece stainless steel chromatography fittings rated to 28,000 psi (1930 bar) is designed for UPLC. The fittings work in standard 10/32 coned ports with ferrule options for both 1/16" and 1/32" OD tubing. * Upchurch...

Hydrophilic PTFE membranes.(Sample Processing Focus)
May 1, 2006... Omnipore membrane is compatible with virtually all solvents, acids, and alkaline solutions. Membrane filters are available as 13 mm, 25 mm, and 47 mm cut disks in pore sizes from 0.1-10 [micro]m. The LCR membrane is manufactured for HPLC...

Low flow, pulseless fluid delivery.(Sample Processing Focus)
May 1, 2006... The CeramPump No-Valve Fluid Control principle combined with Phase-Canceling Technology eliminates pulsation for continuous fluid metering down to 5 [micro]1/min. Fully programmable dispensing system is controlled by precision stepper motors....

Vacuum pumps.(Sample Processing Focus)
May 1, 2006... With a chemical resistant and oil-free PTFE diaphragm, the BuchiVac V-700 and V-710 vacuum pumps are suitable for use with all gases and vapors associated with any lab application. The units come with a choice of a solvent condensing apparatus,...

Steam sterilizers.(Sample Processing Focus)
May 1, 2006... Finn-Aqua GMP GMP Bio Pharma Sterilizers (BPS) are offered in multiple sizes, from 9.7 cubic feet to 294 cubic feet, each with a choice of sterilization cycle options. All units have a choice of the Allen Bradley or Siemens programmable logic...

Conical tube centrifuge adapter.(Sample Processing Focus)
May 1, 2006... Beckman Coulter Allegra X-15R and X-12 Series benchtop centrifuges now feature an adapter that spins 50-ml conical tubes. The adapter accommodates 28 tubes per run in a bio-certified, self-balancing rotor and is suited for cell harvesting and...

Positive displacement pumps.(Sample Processing Focus)
May 1, 2006... Cheminert Model M6 and M50 pumps produce bidirectional pulse-less flow with a range of over six orders of magnitude (10 nl/min to 10 ml/min for the M6; 50 [micro]1/min to 50 ml/min for the M50). The positive displacement units are self-priming...

Tungsten microtools.(Sample Processing Focus)
May 1, 2006... Microtools manufactured from tungsten are hand ground, lapped and polished. Applications for the tools extend to medical research, microscopy, microbiology, micro-biochemistry, specimen manipulation and spectroscopy. The line consists of: a...

2D barcode readers.(Sample Processing Focus)
May 1, 2006... VisionMate Lite 2D bar-code reader plugs into a computer keyboard's PS2 or AT port and automatically transfers data directly to the cursor location in any active application each time a 2D barcoded tube is read. Set-up is simple with no reader...

Liquid delivery assurance service.(Sample Processing Focus)
May 1, 2006... Liquid Delivery Quality Assurance support and consultation suite includes five essential support services: automated liquid delivery equipment qualification and optimization; manual pipetting training and certification; SOP review and...

Vial-cap crimper.(Sample Processing Focus)
May 1, 2006... Micro-XL 4300 bench-top vial cap crimper incorporates a built in adjustment dial, allowing the operator to make incremental adjustments as fine as 0.15 mm to compensate for seal or septa thickness. Settings can be tracked and returned to for...

Stir bar retrieval.(Sample Processing Focus)
May 1, 2006... Handheld Spinbar Restrainer enables users to easily retrieve magnetic stirring bars from vessels. It stops the loss of magnetic stirring bars headed down lab drains and eliminates splashing when pouring out of mixing containers. The tool fits...

Modular furniture system.(Sample Processing Focus)
May 1, 2006... Starsys Mobile Workcenter modular lab furniture system facilitates fast configuration. A robust aluminum and steel-framed substructure has a polymer outer skin. Easy-to-clean, chemical-resistant surfaces will not chip, peel, dent or corrode...

High-speed CMOS cameras.(Sample Processing Focus)
May 1, 2006... MotionPro HS high-speed imaging camera line includes: the HS-3, offering 1000 full frames per second (fps) at 1.3-Mpix resolution; and the HS-4, offering 5000 fps at 512 x 512 resolution. Higher frame rates (to 140,000 fps) are achieved via...

NIH launches clinical studies to investigate rare diseases.(Research News)
May 1, 2006... The National Institutes of Health (NIH) has announced the first clinical studies of its Rare Diseases Clinical Research Network (RDCRN). More than 20 studies are expected to open in the next few months at about 50 sites across the United States...

ExonHit expands SpliceArray line on Affymetrix microarray platform.(Research News)
May 1, 2006... ExonHit Therapeutics has announced that a number of its SpliceArray products are now available on the Affymetrix GeneChip microarray platform. Newly available products include arrays for GPCR, ion channel, nuclear receptors and apoptosis...

Simulation of functioning organism.(Research News)
May 1, 2006... Researchers in Illinois have created an atomic-level simulation of a complete, functioning organism, with the hope that the breakthrough will speed development of new drugs to combat viruses in plants, animals and people. Led by Professor...

EvoGenix in-licenses cancer antibody.(Research News)
May 1, 2006... Antibody therapeutics company EvoGenix Limited has in-licensed an anti-cancer antibody discovered by researchers at the University of Massachusetts Medical School (UMMS). The hamster antibody, DMF10, which was developed by Kenneth L. Rock, MD,...