Bioscience Technology articles from May 2005

Bioscience Technology archives from May 2005

From mice to molecules.(EDITOR'S Note)(BioScience Technology magazine )(Company Profile)
May 1, 2005... BioScience Technology magazine began publishing in 1976, a time when biological research was essentially beginning the modern era. The first recombinant DNA experiments had been carried out in 1973 by Walter Gilbert; the first hybridoma had...

Scientists propose new method for studying ion channel kinetics.(Brief Article)
May 1, 2005... Scientists working at Los Alamos National Laboratory have developed a new method for the study of ion channel gating kinetics. An ion channel is a protein pore that lets ions (charged atoms such as calcium) pass through a cell's membrane. The...

CeNeS and Tripos announce advances in COMT inhibitor discovery program.(Brief Article)
May 1, 2005... CeNeS Pharmaceuticals, a Cambridge, UK based biopharmaceutical company, and Tripos, a provider of drug discovery chemistry and informatics solutions, have agreed to continue collaborating on research on COMT inhibitors. The companies have...

Scientists discover how Ebola virus infects cells.(Brief Article)
May 1, 2005... Ebola virus reproduction in laboratory-grown cells is severely hampered by enzyme-inhibiting chemicals, and these chemicals deserve further study as possible treatments for Ebola virus infections in humans, report scientists supported in part...

Nonlinear dynamics to develop biomarker discovery analysis software.(Brief Article)
May 1, 2005... Nonlinear Dynamics Ltd. has undertaken a large scale development program to evolve a new biomarker discovery product range. Multiple products will be launched for the analysis of mass spectrometry and capillary electrophoresis trace data, and...

Paulette S. Gray to head National Cancer Institute Division of Extramural Activities.(Appointed Paulette S. Gray as director of the Division of Extramural Activities)(Brief Article)
May 1, 2005... The National Cancer Institute has announced the appointment of Paulette S. Gray, Ph.D., as director of the Division of Extramural Activities, effective April 17. Gray served as the acting director and deputy director of the Division of...

Benchtop instrument detects individual miRNA molecules without amplification.(EDITOR'S Choice: MAY'S TECHNOLOGY)(Brief Article)
May 1, 2005... Trilogy 2020 Single Molecule Analyzer (U.S. Genomics) benchtop instrumentation, reagents and software platform directly detects and quantitates individual molecules without amplification. Microfluidics, optical engineering, and labeling...

Rabbit monoclonals for cell signaling.(EDITOR'S Choice: MAY'S TECHNOLOGY)(Epitomics Inc.)(Brief Article)
May 1, 2005... Epitomics has developed a proprietary method for making monoclonal antibodies using rabbits. Rabbit monoclonal antibodies offer specific advantages, including more diverse epitope recognition, improved response to less immunogenic antigens, &...

Chips for proteomics analysis.(EDITOR'S Choice: MAY'S TECHNOLOGY)(Brief Article)
May 1, 2005... SpotReady series chips, from GWC Technologies, Inc., are offered for label-free array analysis of proteins and other biomolecules. These products are designed to work with the company's SPRimager and SPRimagerII systems. SPR imaging systems use...

Automated ADME/Tox system.(EDITOR'S Choice: MAY'S TECHNOLOGY)(Brief Article)
May 1, 2005... LeadStream is an automated system for ADME/Tox screening and and accelerated early-stage drug compound assessment. The platform consists of four distinct elements: three integrated instrumentation modules, plus software that manages the flow of...

Multi-sample, genome-wide expression microarrays.(EDITOR'S Choice: MAY'S TECHNOLOGY)(Brief Article)
May 1, 2005... Illumina Inc. offers two Semrix BeadChips that enable whole-genome and RefSeq-based expression profiling of multiple samples on the same microarray. The new expression offerings, which have undergone extensive testing at customer locations,...

Rabbit monoclonal antibodies.(EDITOR'S Choice: MAY'S TECHNOLOGY)(Brief Article)
May 1, 2005... Vector Laboratories has introduced six, new rabbit monoclonal antibodies to their line of primary antibodies for immunohistochemical staining: CD3, COX-2, Cyclin D1, Ki67, Estrogen Receptor, and Progesterone Receptor. Many rabbit monoclonal...

Cell manipulator for fusion, nuclear transfer, electroporation.(EDITOR'S Choice: MAY'S TECHNOLOGY)(BTX--Harvard Apparatus)(Brief Article)
May 1, 2005... The BTX/Harvard Apparatus ECM2001 Electro Cell Manipulator is a tool for gene transfer and cell fusion of a variety of plant, animal and bacterial cells. System functions are tailored for in vivo and in vitro experiments resulting in...

Pre-validated RNAi vector sets.(EDITOR'S Choice: MAY'S TECHNOLOGY)(Brief Article)
May 1, 2005... BD Knockout Gene-Specific Kits provide ready-to-use shRNA vectors functionally proven to knock down expression of a specific gene. The shRNA vectors allow users to choose either a transfection or a viral infection delivery method. Each kit...

Lighting up cells: imaging techniques provide multiplexing, multiplicity, statistical validation, and a big-picture approach to cell biology.(Cover Story)
May 1, 2005... Life scientists seeking the "big picture" are recognizing the value of cell imaging techniques. Automated cell imaging arose from the need for more sophisticated drug discovery tools, principally at pharmaceutical and biotech companies....

Multi-Angle Light Scattering Detector.(TECHNOLOGY Focus: BIOANALYTICAL INSTRUMENTATION)(Brief Article)
May 1, 2005... DAWN HELEOS Multi-Angle Light Scattering (MALS) Detector (Wyatt Technology) can incorporate both MALS and QELS (Quasi-Elastic Light Scattering). Offering more than twice the sensitivity of Wyatt's DAWN EOS, the new HELEOS is capable of...

HPLC system.(TECHNOLOGY Focus: BIOANALYTICAL INSTRUMENTATION)(Brief Article)
May 1, 2005... Thermo Electron Corp.'s Finnigan Surveyor Plus HPLC system benefits from a stackable and modular design. The system features an integrated column oven and the ability to use vials or plates. Patented LightPipe technology ensures sensitivity...

Microwave synthesis with real-time monitoring.(TECHNOLOGY Focus: BIOANALYTICAL INSTRUMENTATION)(Brief Article)
May 1, 2005... CEM's Investigator provides an integrated approach for real-time reaction monitoring and microwave-enhanced synthesis. The technology allows chemists to analyze samples in real time in original reaction vessels during the microwave irradiation...

High-content imaging system.(TECHNOLOGY Focus: BIOANALYTICAL INSTRUMENTATION)(Brief Article)
May 1, 2005... Cell Lab IC 100 Image Cytometer provides high-throughput imaging and analysis of cell populations. Signaling cascades, translocation, protein tracking, migration and surface and receptor activation events can be identified. Processes can be...

FT-IR spectrometer.(TECHNOLOGY Focus: BIOANALYTICAL INSTRUMENTATION)(Brief Article)
May 1, 2005... The Nicolet 380 FT-IR spectrometer seamlessly integrates spectrometer, software, accessories and service and provides good results for infrared testing requirements. The instrument's accuracy enhances productivity with ease through continuous...

Plate reader accessory reduces sample volume.(TECHNOLOGY Focus: BIOANALYTICAL INSTRUMENTATION)(Brief Article)
May 1, 2005... An accessory for the Varian Cary 50 ultraviolet-visible (UV-Vis) spectrophotometer reduces the volume of sample required for analysis. The instrument can now perform wavelength scans from 190 nm to 1100 nm in up to 384 samples in micro-liter...

Mass spectrometers.(TECHNOLOGY Focus: BIOANALYTICAL INSTRUMENTATION)(Brief Article)
May 1, 2005... Applied Biosystems, together with MDS Sciex, has introduced the 3200 Q TRAP System, a hybrid triple quadrupole-linear ion trap mass spectrometer for small molecule identification, characterization and quantification, and for protein bio-marker...

LC/MS.(TECHNOLOGY Focus: BIOANALYTICAL INSTRUMENTATION)(Liquid Chromatograph/ Mass Spectrometer )(Brief Article)
May 1, 2005... LCMS-2010EV Liquid Chromatograph/ Mass Spectrometer incorporates an enhanced ion source design that uses an additional drying gas at the inlet of the capillary, resulting in high sensitivity and control of solvent adduct formation. Additional...

Fluorescence lifetime reader.(TECHNOLOGY Focus: BIOANALYTICAL INSTRUMENTATION)(Brief Article)
May 1, 2005... Fluorescence lifetime plate reader Nano-Scan FLT offers selectable excitation and emission wavelengths from 337 nm to 820 nm, and is compatible with 24-, 48-, 96-, 384- and 1536-well plates. The device is capable of measuring at the nanosecond...

HPLC detector.(TECHNOLOGY Focus: BIOANALYTICAL INSTRUMENTATION)(ESA Biosciences, Inc)(Brief Article)
May 1, 2005... Corona Charged Aerosol Detector provides dynamic detection over four orders of magnitude, consistent response factors independent of chemical structure, and full gradient capability, for almost complete universality in HPLC. Charged Aerosol...

Ion trap mass spectrometer.(TECHNOLOGY Focus: BIOANALYTICAL INSTRUMENTATION)(Brief Article)
May 1, 2005... The 1100 Series LC/MSD Trap XCT Ultra ion trap mass spec offers improved scan cycle times, enabling collection of mass spectra at rates up to three times faster than its predecessors. Instrument resolution speed and sensitivity make it suited...

Cartridges for micro parallel LC.(TECHNOLOGY Focus: BIOANALYTICAL INSTRUMENTATION)(Brief Article)
May 1, 2005... Brio cartridges, for Nanostream's Veloce micro parallel liquid chromatography (microPLC) system, are available in a range of stationary phases for high analyte selectivity. Inserted into the system, they enable multiple simultaneous...

Confocal Imager.(TECHNOLOGY Focus: BIOANALYTICAL INSTRUMENTATION)(Brief Article)
May 1, 2005... BD CARV II Confocal Imager offers CCD confocal imaging in an easy to use optical package that can be attached to new or existing microscopes. High-speed, multi-pinhole, confocal scanning combined with high quantum efficiency CCD cameras allows...

Peristaltic pumps.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... Watson-Marlow Bredel 400 series single, dual, and multi-channel peristaltic pumps are offered for applications where sizes can range from microliters to hundreds of milliliters per minute. These pumps compliment the existing product line, with...

Personal evaporator.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... EZ-Bio evaporator, for low to medium boiling point solvents, provides pre-programmed methods for DNA purification and extraction oligosynthesis, protein purification and removal of aqueous mixtures. There is a method for HPLC fractions such as...

UV system converts tap water into pure water.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... RiOs-DI 3 UV water purification system is offered for low volume routine laboratory applications ranging from buffer. reagent and culture media preparation to general washing. High quality product water (> 10 M[ohm] x cm and less than 50 ppb...

Pass-Thru Biological Safety Cabinets for animal labs.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... Pass-Thru System Biological Safety Cabinets feature a differential pressure design that offers vivarium protection for animals and lab personnel. This thru-the-wall animal transfer and receiving system uses The Baker Co.'s standard SterilGARD...

Labeling-Tape Dispensers.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... Write-On Labeling Tape Dispensers keep a fresh length of label tape waiting on a smooth writing platform, ready to be marked. Labels are neat and consistent as the problem of writing on curved or irregular surfaces is avoided. An accurate label...

pH/temperature electrode.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... InPro 3253 pH/ temperature electrode is a pre-pressurized, liquid-filled, reference system in a hygienic, compact, low-maintenance design. The ceramic micropore diaphragm makes measurement at process pressure up to 58 psig possible. The...

Shaker for plastic containers.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)
May 1, 2005... KUEHNER Shakers accommodate several different plastic containers, feature a maintenance free magnetic drive, an orbital movement of 2" and speed adjustable from 20 to 300 rpm. BioPro International Inc., 516-249-0099, www.biopro.com For...

Infusion-only syringe pump.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... PHD 22/2000 infusion-only syringe pump offers linear force through a flow rate range of 0.0001 [micro]l/hr to 220.8 ml/min and holds syringes from 0.5 [micro]l to 140 ml. Accurate to 0.35%, the pump features a 2-syringe rack that holds many...

9-port manifolds.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... Two 9-port manifolds are offered with a selection of low pressure manifolds. They are split flow in eight directions, e.g., for infusion onto a 96-well plate. With 1/4 to 28 flat-bottom ports, the manifolds come in versions for 1/16" and 1/8"...

Horizontal Laminar Flow Clean Bench.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... Series 204 Horizontal Laminar Flow Clean Benches include an internal motorized filter unit for full filter coverage and three-side access for easy cleaning. Sizes range from 2 x 2 ft. to 2 x 6 ft. The benches are installed on an existing...

Horizontal, swing-out centrifuge.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(LW Scientific, Inc.)(Brief Article)
May 1, 2005... Straight 8-5K horizontal, swing-out centrifuge ensures straight line separations for accurate processing. The 8-place centrifuge is outfitted with a microprocessor and reaches speeds up to 5000 rpm and g-forces to 4000 Xg. Zero-rpm interlocking...

Glassware washer.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... The 910 LX glassware washer offers a small footprint, chamber flexibility with interchangeable racks and adjustable levels, and rack compatibility with a family of washers. Features include an automatic door closing system, ergonomic loading...

Freezer security system.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... CryoSecure Proximity Card Access System provides safe, secure and controlled access to Harris upright ultra-low temperature freezers. Available as an option on new models or as a field upgrade to ultra-low temperature freezers fitted with the...

Ultrasonic liquid processors.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... The VCX 130 130-watt ultrasonic processor features automatic tuning and an energy (joules) monitor, is microprocessor-based, and provides a full function timer and an independent on/off pulser. Applications include cell disruption, sample prep,...

Bead Mill.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... Bead Mill MM 301 prepares small batches of various samples in the 40 to 60 micron range. It is suited for homogenizing with the wax, flux or other binders prior to pelletizing or the fusion technique. Grinding sets are available from 1.5 ml to...

Nanoliter syringe pump.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(KD Scientific Inc)(Brief Article)
May 1, 2005... Nanoliter syringe pump 310 Plus works with syringes from 0.5 [micro]l to 250 [micro]l with accurate pulseless flow delivery from 1 nl/min to 363.7 p [micro]1/hr. A remote injector allows the user to deliver small volumes without wasting...

Vertical Clean Bench.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... Purifier Vertical Clean Benches are available for tissue culture and media plate preparation under ISO Class 5 conditions to prevent airborne contamination. It does not provide user protection so should not be used in conjunction with...

Universal centrifuges.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... The air-cooled Z383 and refrigerated Z383-K universal centrifuges feature a total maximum capacity of 2000 ml (4 ml x 500 ml) in the swing out rotor. Inserts for this rotor are available to centrifuge a large quantity of tubes, including 28 x...

Vortex mixers.(TECHNOLOGY Focus: LABORATORY EQUIPMENT)(Brief Article)
May 1, 2005... Mixers in the Mini Vortex line are suited for use with test tubes, flasks, beakers and a range of small containers. The Touch vortex mixer is a one-touch unit with a fixed speed of 3200 rpm designed for high speed mixing of samples. Analog...

Image analysis software integrates digital and analog devices.(TECHNOLOGY Focus: BIOINFORMATICS)(Brief Article)
May 1, 2005... The IO-Pro Plug-in Module for Image-Pro Plus software (Media Cybernetics) can be used to obtain additional contextual data from imaging experiments. IO-Pro enables control of analog and digital outputs for external equipment control; analog...

IBM provides on-demand access to Blue Gene supercomputer.(TECHNOLOGY Focus: BIOINFORMATICS)(International Business Machines Corp.)(Brief Article)
May 1, 2005... IBM has announced the availability of its world renowned Blue Gene supercomputing system, the most powerful supercomputer, at its newest Deep Computing Capacity on Demand Center in Rochester MN. The new center will allow customers and partners...

Software applications for mass spectrometry data system.(TECHNOLOGY Focus: BIOINFORMATICS)
May 1, 2005... Open Access and Discovery software applications are available for the Thermo Electron Corp. Xcalibur 1.4 SR1 mass spectrometry data system. These applications can be used with any Finnigan ion trap or quadrupole mass spectrometer as well as...

Array analysis software.(TECHNOLOGY Focus: BIOINFORMATICS)(Brief Article)
May 1, 2005... Insightful Corp. has announced the release of two new products. S-PLUS 7 is an update to the S-PLUS software platform for statistical data analysis and predictive analytics. This package enables analysis of very large data sets and the rapid...

Pathways analysis application adds workgroup functionality.(TECHNOLOGY Focus: BIOINFORMATICS)(Ingenuity Systems)(Brief Article)
May 1, 2005... Ingenuity has announced release of Sharing and Workgroups in Ingenuity Pathways Analysis has added new Sharing and Workgroups functionality, which facilitates communication of analysis results between colleagues. Pathways Analysis is available...

IBM provides on-demand access to Blue Gene supercomputer.(TECHNOLOGY Focus: BIOINFORMATICS)(Brief Article)
May 1, 2005... IBM has announced the availability of its world renowned Blue Gene supercomputing system, the most powerful supercomputer, at its newest Deep Computing Capacity on-Demand Center in Rochester, MN. The new center will allow customers and...

Reagent product software.(TECHNOLOGY Focus: BIOINFORMATICS)(Teranode Corp)(Brief Article)
May 1, 2005... TERANODE Reagent Production software supports reagent production control, QA, and reporting. (Other solutions to be released in 2005 include TERANODE Pathway Analytics, TERANODE Sample Processing, and TERANODE HTS.) Productivity within each...

Custom microarray design Web portal.(TECHNOLOGY Focus: BIOINFORMATICS)(Brief Article)
May 1, 2005... The eArray 3.0 secure Web portal is available for the design of custom microarrays that will be used in drug discovery, disease studies and basic research. This free, on-line tool enables scientists to design their own microarrays with...

Lab, LIMS software link.(TECHNOLOGY Focus: BIOINFORMATICS)(Brief Article)
May 1, 2005... Scientific Software, Inc. (SSI) and Labtronics Inc. have announced the development a connectivity module integrating LimsLink and OpenLAB. LimsLink for OpenLAB provides an off the shelf solution for integrating third party LIMS systems to SSI's...

Molecular structure optimization.(TECHNOLOGY Focus: BIOINFORMATICS)
May 1, 2005... SZYBKI 1.0 (pronounced shib'kee) optimizes molecular structures with the Merck Molecular Force Field, either with or without solvent effect, to yield quality 3D molecular structures. SZYBKI will also refine portions of a protein structure and...

Linux-based high-performance visual computing system.(TECHNOLOGY Focus: BIOINFORMATICS)
May 1, 2005... Silicon Graphics Prism is a flexible Linux OS-based visual computer product combines standards-based Intel Itanium 2 processors, the Linux operating environment, and graphics technology. Real-world applications such as cancer and proteomics...

Patent Chemistry Database.(TECHNOLOGY Focus: BIOINFORMATICS)
May 1, 2005... The MDL Patent Chemistry Database contains 1.5 million structure-searchable chemical reactions and over 1.6 million organic, inorganic, and organometallic compounds and associated information taken from approximately 340,000 organic chemistry...

Thermal cycler.(TECHNOLOGY Focus: AMPLIFICATION TECHNOLOGIES)
May 1, 2005... MultiGene II personal-sized thermal cycler is useful for applications ranging from DNA amplification to constant temperature incubations. Two models accommodate 16 ml x 0.5 ml tubes and 25 ml x 0.2 ml tubes. Cycling parameters are entered using...

384-well Thermal Cycler plates.(TECHNOLOGY Focus: AMPLIFICATION TECHNOLOGIES)
May 1, 2005... For high-throughput Polymerase Chain Reaction assays, 384-well Thermal Cycler plates are compatible with the majority of 384-block PCR and sequencing instruments. To ensure full compatibility with robotic systems, the plates offer a full plate...

Polymerase mix.(TECHNOLOGY Focus: AMPLIFICATION TECHNOLOGIES)
May 1, 2005... RubyTaq PCR Master Mix is supplied as a 2x pre-mixed formulation containing Taq DNA polymerase, ultrapure nucleotides, reaction buffer, and two inert dyes optimized for a variety of PCR applications. Neither loading dyes nor compounds that...

96- and 384-well plates.(TECHNOLOGY Focus: AMPLIFICATION TECHNOLOGIES)
May 1, 2005... Multiply 96- and 384-well plates for PCR applications accommodate common thermal cyclers, real-time PCR systems and DNA sequencers. Black alphanumeric grids facilitte sample identification. Slightly raised wells provide effective plate sealing...

Real-time monitoring of cell-based assays using electronic cell sensor technology.(APPLICATION Note)
May 1, 2005... In order to fully understand, appreciate and measure biological and cellular processes, it is necessary to use a system that is non-invasive and provides kinetic data regarding the dynamic nature of cellular response to certain challenges such...

Infusion/withdrawal pump.(NEW Technology)
May 1, 2005... The Pump II Pico Plus (70 to 2213) features infusion and withdrawal capabilities, as well as smooth and accurate picoliter, nanoliter, microliter and milliliter flows. Injection rate can be changed from 0.0550 pl/sec to 7.3 [micro]l/sec. This...

siRNA design service.(NEW Technology)
May 1, 2005... New siRNA service offers four siRNAs targeting a gene of choice designed using an algorithm licensed from Novartis Pharmaceuticals, and provided with a guarantee that at least two of the four siRNAs will result in efficient knockdown. The...

Bovine IL-1[beta] antibodies.(NEW Technology)
May 1, 2005... Unlabeled and biotin-labeled bovine IL-1[beta] antibodies polyclonal antibodies are offered by Pierce Biotechnology under its Endogen brand. They are validated as capture and detection antibodies, respectively, for ELISA development. Bovine IFN...

Agarose gel band picker.(NEW Technology)
May 1, 2005... Band picker simultaneously excises 8 bands from an agarose gel for repetitive clone selection/ screening. Bands are the same diameter and thickness. Disposable tips are used preventing cross contamination. The Gel Co., 800-256-8596,...

Ultrasonic Flow Cell.(NEW Technology)
May 1, 2005... Continuous Ultrasonic Flow Cell treats low viscosity samples for emulsification, dispersion and homogenization. The chamber provides the sample with uniform exposure to the ultrasonics, allowing throughput volumes to 20 1/hour. Continuous flow...

Shaking, mixing apparatus.(NEW Technology)
May 1, 2005... PRO Lab Plus Series equipment includes the VSN-5 Nutating Mixer, the VSM-3 Vortex Mixer, the VSOS-4 Orbital Shaker and the VSR-50 Variable Speed Rocker. A variety of accessories facilitate instrument integration into current lab procedures. Pro...

The FastPrep[R] System: time-tested and reliable sample lysis.(Advertisement)
May 1, 2005... Hundreds of published papers from a wide range of research applications reference the FastPrep[R] System as the answer to lysis of difficult samples for the purification of DNA, RNA and protein. FastPrep[R] Instruments and Kits, first...

The leading imaging system in fluorescence microscopy.
May 1, 2005... With Axio Imager, Carl Zeiss is launching its new generation of upright imaging systems that have been specially tailored to the demands of fluorescence microscopy. Thanks to its incredible flexibility and user-friendliness, Axio Imager is...

RNA research: focused on gene expression.(30 Years of Innovation and Research)
May 1, 2005... Researchers studying development, diseased cells versus normal cells, and other complex biological systems have an increasing need to analyze gene expression in individual cells. The most common method for measuring gene expression uses...

30 years of innovation and research.
May 1, 2005... 1975 Georges Kohler and Cesar Milstein fuse antibody-producing B lymphocyte ceils with tumor coils to produce the first monocional antibodies. 1976 Genentoch, Inc., founded, by Robert Swanson and Herbert Boyer. 1977 ...

A novel peptide hydrogel for optimizing 3D cell culture environments.(Advertisement)
May 1, 2005... BD Biosciences now offers a unique biomaterial that is suitable for a variety of cell biology and tissue engineering applications. BD[TM] PuraMatrix[TM] Peptide Hydrogel is a synthetic amino acid-based three-dimensional (3D) hydrogel that was...

Are cells logical machines?(30 Years of Innovation and Research)
May 1, 2005... Mammalian and other eukaryotic (nucleated) cells monitor their internal and external environments through specialized biochemical pathways--collections of interacting protein molecules that detect physical and chemical signals and transmit this...

Do biologists really need mass spectrometry?(30 Years of Innovation and Research)
May 1, 2005... With the development of ionization methods and detector technologies over the past 30 years, mass spectrometry has migrated from dedicated core facilities into biology labs and to the forefront of contemporary biology research. Leading...

Framing the future of digital image analysis.(30 Years of Innovation and Research)
May 1, 2005... Innovations in digital imaging will have a profound influence on bio-research in the years to come, making possible new discoveries with global benefits. Light-based imaging has always been used extensively in biological research and recent...

Signaling network mapping in single cells.(30 Years of Innovation and Research)
May 1, 2005... Reversible protein phosphorylation, principally on serine, threonine or tyrosine residues, is one of the most important and well-studied post translational modifications. An assortment of kinases and phosphatases regulate intracellular...

The continuing evolution of DNA sequencing.(30 Years of Innovation and Research)
May 1, 2005... In the 1970s, as Dr. Fred Sanger and his colleagues developed DNA sequencing techniques still in use today, no one could have predicted that thirty years later we would witness a time when genomes could be sequenced in less than a week. ...

1 [micro]l micro-spectrophotometry: a versatile and enabling technology: the NanoDrop[R] ND-1000 Spectrophotometer's novel sample retention system enables full spectrum UV/Visible spectroscopy with a single microliter ([micro]l) of sample eliminating the need for cuvettes, capillaries, or dilutions.
May 1, 2005... Rapid advances towards smaller-scaled assays in microgenomics, proteomics, and drug discovery programs, demand versatile instrumentation optimized for microvolumes. The NanoDrop[R] ND-1000 Spectrophotometer allows micro-quantitation by...

Microarrays: from concept to clinic.(30 Years of Innovation and Research)
May 1, 2005... With the 2000 completion of the human genome sequence, information converged with innovation. Access to accurate sequence information enabled higher-confidence design of microarray probe sequences and provided fuel for explosive market growth....

Proteomics growth in prep and purification.(30 Years of Innovation and Research)
May 1, 2005... When asked the question, "how will technology drive growth in proteomics?" I first gave pause to reflect on whether the application was driving technology or whether technology was guiding the application. Although I prefer to think that...

Highly sensitive dsDNA quantitation using fluorescence detection on a TRIAD multimode reader.(Advertisement)
May 1, 2005... Detecting and quantitating small amounts of DNA is extremely important in a wide variety of biological applications. These include standard molecular biology techniques, such as synthesizing complementary DNA (cDNA) for library production and...