Bioscience Technology articles from March 2008

Bioscience Technology archives from March 2008

Microscopists focus on the future.(Cover Story)
March 1, 2008... [ILLUSTRATION OMITTED] Ask the average person to picture a biomedical researcher at work, and the mental image will probably include a figure in a clean, white lab coat, seated at a microscope. Visit the average biomedical research lab,...

Snapshot.
March 1, 2008... Challenges Faced By Life Science Researchers Tighter time requirements 60.9 Pressures for productivity 58.4 Pressures to reduce costs 54.0 Obtaining grants 49.1...

You said it.(Editor's Note)
March 1, 2008... We have just completed a fairly large readership study called Trends in the Adoption of Life Science Technology: 2008. The results of this study will be reported in a supplement mailed with our April Issue. In a section on the role of...

In vivo optical molecular imaging.(March's Innovations)
March 1, 2008... [ILLUSTRATION OMITTED] The KODAK In-Vivo Multispectral Imaging System FX locates and monitors changes in molecular activity of specific cells or organs long before morphological changes can be detected. In vivo optical molecular imaging...

Preclinical molecular imaging system.(March's Innovations)
March 1, 2008... [ILLUSTRATION OMITTED] The desktop MollyQ-50G images small mice, rats and other small animals for studying the behavior and effects of drugs. The system uses scanning focused collimators instead of pinholes and gamma cameras, making it...

Microarray dye.(March's Innovations)
March 1, 2008... [ILLUSTRATION OMITTED] Amersham HyPer5 fluorescent dye, for gene expression and aCGH applications, is an optimized microarray dye that performs consistently irrespective of environmental conditions and number of scans. Photo and ozone...

Purification of synthetic DNA/RNA.(March's Innovations)
March 1, 2008... [ILLUSTRATION OMITTED] Clarity QSP system, for the purification of synthetic DNA/RNA, delivers nearly impurity free, concentrated full-length oligonucleotide sequences. The system is offered in three cartridge formats and in 96-well...

Control of live cell imaging experiments.(March's Innovations)
March 1, 2008... [ILLUSTRATION OMITTED] ONIX Dynamic Cell Culture Platform provides control over live cell imaging experiments by allowing them to change exposure solutions with nanoliter precision It integrates with existing microscope set-ups to allow...

Synthetic cell culture matrix.(March's Innovations)
March 1, 2008... [ILLUSTRATION OMITTED] Biocompatible HyStem hydrogels are available for the expansion of human embryonic stem cells, CD34+ stem cells, and hepatic stem/progenitor cells. The synthetic matrix can be used in a xeno-free cultivation system....

RNA stabilization and preservation.(March's Innovations)
March 1, 2008... RNAstable directly preserves and stabilizes purified RNA samples at room temperature for at least six months and has demonstrated an equivalent of three and a half years stability under accelerated aging conditions. The product was developed...

Imaging plate readers.(March's Innovations)
March 1, 2008... [ILLUSTRATION OMITTED] The FDSS7000, new to the FDSS cell-based assay instrument line, uses fluorescence probes, offers a 1536 dispenser with disposable tips, automatic tip loading, and a multi-washing unit equipped with ultrasound. The...

Web site for women's health research.(Research News)(Website overview)
March 1, 2008... A new Web resource providing consumers with the latest information on significant topics in women's health research from scientific journals and other peer-reviewed sources is now available through the National Library of Medicine (NLM). The...

Implanted device captures stem cells from blood stream in live rats.(Research News)
March 1, 2008... Working for the first time with an adhesion protein-coated device implanted directly into the bloodstream, CellTraffix researchers were able to capture a significant amount of adult stem cells directly from living rats, the British Journal of...

Crystallization method facilitates protein structure study.(Research News)
March 1, 2008... Researchers at the Midwest Center for Structural Genomics (MCSG), the Structural Genomics Consortium (SGC) and the Structural Biology Center (SBC) at the U.S. Department of Energy's Argonne National Laboratory have developed a new technique for...

Scripps gets a jump on HIV vaccine.(Research News)
March 1, 2008... Researchers at The Scripps Research Institute have developed a new two-punch strategy against HIV and have successfully tested aspects of it. Their study, which appeared online the week of Feb. 25 in the Proceedings of the National Academy...

MALDI-TOF mass spectrometers.(Mass Spectrometry Focus)
March 1, 2008... [ILLUSTRATION OMITTED] Three systems have been added to the AXIMA MALDI TOF mass spectrometers (MS) line. The AXIMA Performance mass spectrometer provides high-energy MS/MS interrogation of proteomic, biological and organic sample,...

Quadrupole, orthogonal acceleration TOF MS.(Mass Spectrometry Focus)
March 1, 2008... The SYNAPT MS system is a quadrupole orthogonal acceleration (oa) time-of-flight (TOF) mass spectrometry (MS) platform. The instruments provides detailed characterization and increased productivity in applications such as proteomics,...

Qq-TOF mass spectrometer.(Mass Spectrometry Focus)
March 1, 2008... [ILLUSTRATION OMITTED] micrOTOF-Q II Qq-TOF mass spectrometer provides accurate mass LC/MS/MS performance in proteomics, biomarker profiling, metabolomics and other small molecule applications. On-the-fly SmartFormula 3D method facilitates...

Metabolite identification software.(Mass Spectrometry Focus)
March 1, 2008... [ILLUSTRATION OMITTED] LightSight Software Version 2.0 (Applied Biosystems/MDS SCIEX) for metabolite identification enables quick and accurate screening of drug candidates. Intuitive design provides efficient workflows to identify and...

Determination of fluorescence excitation and emission peaks for Qdot nanocrystals.(Instruments & Systems)
March 1, 2008... Introduction Quantum dots are made of nanocrystals, semiconductor materials that are roughly the size of proteins (10-20 nm). Qdot nanocrystals (Invitrogen Corp., Carlsbad, CA) are a specialized form of nanocrystal composed of a core,...

Tissue imaging with MALDI mass spec.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] MALDI LTQXL mass spectrometer with ImageQuest software can be used to analyze whole tissue, biological and polymer samples without extensive sample preparation. The addition of MALDI (matrix-assisted laser...

Sample management software.(Product News)
March 1, 2008... SampleWare Version 3.0 database software, for storing and organizing sample information, provides tools that facilitate uploading, tracking and retrieving sample data. The database can be customized, allowing data to be matched to specific...

Online collaboration tool.(Product News)
March 1, 2008... LabLinker is a free system for sharing sequence and research information that can also be used for consolidating orders. In addition to the collaborative features available, customers working together can consolidate their orders to avoid...

2D Electrophoresis.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] 2D System includes an IEF100 First-dimension Isoelectric Focusing Unit and an SE900 Second-dimension Gel Electrophoresis Unit. The IEF100 helps increase the quality and speed of IEF separations, and the SE900's...

Column characterizes, purifies proteins.(Product News)(Column)
March 1, 2008... [ILLUSTRATION OMITTED] The Jupiter 3 [micro]m C18 300 [angstrom] HPLC column enables the separation of closely eluting proteins. It resolves post-translational modifications and is ideal for research on proteins such as Cytochrome C,...

Pressure Volume Loop Software.(Product News)
March 1, 2008... LabScribe2 Pressure Volume Loop Software, a plug-in software module for this company's data acquisition systems, facilitates the measurement and analysis of hemodynamic parameters of cardiac and pulmonary pressure and volume data acquired by a...

Imaging microscopy software.(Product News)
March 1, 2008... NIS-Elements C enables full integration of confocal specific acquisition controls together with advanced image analysis functionality. Its dedicated interface for Nikon Instruments A1 confocal microscope automation addresses all of the various...

Cryostat.(Product News)
March 1, 2008... The CM1950 cryostat incorporates a CryoZone cooling system, which controls a zone of uniformly cool air in the critical areas of the cryochamber. The cool air circulates around the specimen, knife, and anti-roll guide to create conditions for...

Sample and assay processing platform.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] QIAsymphony SP is the first in a series of modular instruments that can be integrated to automate entire workflows in a range of molecular sample and assay applications. Many kinds of samples can be loaded in many...

Digital microscopy platform.(Product News)
March 1, 2008... Ikoniscope provides automated slide handling, slide scanning, real-time image capture and analysis and unattended enumeration and classification of cellular nuclei. The automation of standard tests and rare cell detection applications are...

Small RNA, Gene Expression profiling.(Product News)
March 1, 2008... Two Digital Gene Expression applications offer a platform for RNA discovery, accurate quantification of low-abundance messenger RNA, and measurement of gene expression in any species without the need for prior sequence knowledge. Digital Gene...

Microbiology imaging software.(Product News)
March 1, 2008... ProtoCOL V1.4 colony counting and inhibition zone sizing software automates many routine plate-based image analysis tasks. The software analyzes images of the same or different colored colonies on pour, spiral or surface inoculated plates and...

GC/MS software.(Product News)
March 1, 2008... PerkinElmer TurboMass 5.4 GC/MS software is designed for a variety of application needs. It provides features and functionalities such as QA/QC method evaluation, environmental CLP-like reporting, customized reporting and more. TurboMass 5.4...

Isolate DNA from whole blood.(Genomics Focus)
March 1, 2008... [ILLUSTRATION OMITTED] MasterPure DNA Purification Kit for Blood, Version II, can be used to isolate extremely pure genomic DNA from whole blood or buffy coat. The optimized protocol can isolate up to 100 [micro]g of DNA from 600 pl of...

miRNA microarray.(Genomics Focus)
March 1, 2008... [ILLUSTRATION OMITTED] Newly updated NCode Human miRNA Microarray V3 facilitates the screening of a comprehensive collection of human miRNAs. Arrays are spotted in triplicate with positive and negative controls throughout for monitoring...

Mitotic Assay Kits.(Genomics Focus)
March 1, 2008... [ILLUSTRATION OMITTED] Mitotic Assay Kits make it easy to determine the percentage of cells undergoing mitosis within a specific population. Three different kits for assaying mitosis are offered, and differ primarily in their readout. The...

Cell lines for transfection.(Genomics Focus)
March 1, 2008... [ILLUSTRATION OMITTED] Expresso Single-Shot and Double-Shot Mammalian Cell Lines are offered for rapid, efficient transfection. The HeLa, HEK-293, CHO-K1, NIH-3T3 and COS-7 Mammalian Cells are pre-counted, pre-aliquoted versions of their...

Synthesis of long peptides: native chemical ligation permits the chemoselective ligation of unprotected peptide fragments in aqueous buffer. Ligation occurs between a peptide containing a cysteine at its N-terminus and another peptide modified with a thioester at its C-terminus.(Biochemicals & Kits)
March 1, 2008... Introduction The attraction of peptides as therapeutics or research tools comes from their high specificity to targeted sites, their diversity and their usually low toxicity. As the demand for peptides increases, and the price of raw...

Competent cells.(Product News)
March 1, 2008... [GRAPHIC OMITTED] Line of competent cells for cloning and expression includes both high value DH5[alpha] (chemically competent) and high efficiency TG1 (electrocompetent) cells. Strains available for cloning include E. cloni 10G (DH10B)...

Tissue engineering scaffolds.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] BIOFELT is a bioabsorbable polymer fiber scaffold that is highly porous, soft and flexible, biocompatible and enables human cells to grow into its 3D interconnected pores so that new natural tissue can be formed to...

FISH reagents and kits.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] CytoGenetix reagents are available for fluorescent in situ hybridization (FISH). Developed to integrate with the Applied Imaging CytoVision imaging and analysis system, the reagents are effective and well-suited for...

Protein-protein interaction in yeast.(Product News)
March 1, 2008... This line of products, kits, and services for research on protein-protein interactions in yeast includes pre-mixed yeast growth media, in vivo assays for protein-protein interactions in yeast, and nucleic acid purification products, as well as...

DNA isolation kit.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] This kit isolates DNA from any volume of whole blood. Samples from 300 microliters to 1000 ml can be used. The method separates lymphocytes and lyses them to recover pure genomic DNA that is ready for use in...

Fluorescent conjugates.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] KODAK X-SIGHT Large Stokes Shift Dye Conjugates for fluorescent in vitro and in vivo imaging applications are easy to use and are recommended for Western blotting applications. They are available conjugated to a...

Primer assays for miRNA quantification.(Product News)
March 1, 2008... miScript Controls, six validated primer assays,' enable normalization of real-time PCR results in miRNA quantification studies. The products are specific for several small nucleolar RNAs and small nuclear RNAs. Each miScript Control is...

-86[degrees]C freezers.(Refrigerator/Freezer Focus)
March 1, 2008... [ILLUSTRATION OMITTED] Revco PLUS -86 C upright freezers offer maximum heat removal capacity to provide rapid temperature recovery after door openings. A low amount of power is required to properly maintain cabinet temperature, which...

Energy efficiency refrigeration options.(Refrigerator/Freezer Focus)
March 1, 2008... [ILLUSTRATION OMITTED] An "Energy Efficiency Option" is being added to all scientific refrigerators from Powers Scientific, Inc.. The option includes door activated lighting, high efficiency fan motors and triple glass doors. At 5 C,...

Upright freezer.(Refrigerator/Freezer Focus)
March 1, 2008... MDF-U730M storage freezer for long-term preservation and storage of biologics, provides the features necessary for freezing enzymes and vaccines, including temperature uniformity, microprocessor control, and flexible capacity. Two access ports,...

Ultra-low temperature freezers.(Refrigerator/Freezer Focus)
March 1, 2008... [ILLUSTRATION OMITTED] Offered in two lines and ten models, including an on-or-under bench upright, NBS Innova and Premium line -86 C freezers provide rigid control and rapid recovery after door opening. Front-mounted controls are set at...

Refrigerators, freezers with low C[O.sub.2] output.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] Futura refrigerators and freezers require 45% less energy than standard lab refrigerators, reducing the life cycle air pollution by 26,556 lbs of C[O.sub.2]. The units include digital display with high/low set point...

Centrifugal evaporator.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] EZ-2 Series II centrifugal evaporator allows unattended operation and can be used without training. Available in three capacities (50, 125 and 300 mL), SampleGenie enables EZ-2 and HT series evaporators to accelerate...

Printing, labeling system.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] Battery-powered Spirit 2100 handheld-printing system provides thermal transfer printing for permanent labels that can be used for the labeling of tubes, vials, plates and slides. It provides an alternative to...

Radiometer/photometer.(Product News)
March 1, 2008... AccuMAX Series digital radiometer/photometers provide accurate readouts for UV irradiance, visible illuminance and luminance light readings. The units are calibrated for use with a line of interchangeable sensor detectors. When equipped with a...

Oxygen meter.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] Model 782 oxygen meter acts as a stand alone unit or as an interface to respirometry/monitoring software running on a PC. It accepts inputs from either one or two Clark type 1302 microcathode oxygen electrodes and...

Filter plates improve assay results.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] [MultiScreen.sub.HTS] + filter microplates, offered for radiometric kinase and GPCR assays, have a mesh backing that creates uniformly flowing wells and improves washing efficiency. The design reduces overall...

Pump with electronic transmission.(Product News)
March 1, 2008... The Nexus 3000 pump can be used for virtually any application involving metered fluid delivery due to its electronic transmission, which can reach both low (0.5 picoliter/min) and high speeds (0.5 liters/min) without being limited by fixed...

Capture, count, characterize rare cells.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] CellCapture CTC (circulating tumor cell) Mouse/Rat Kit Uses CellTracks instruments and reagents to add this predictive biomarker to the toolbox of scientists who study cancer in animal models. A 50 [micro]L sample...

Tray dryer, lyophilizer.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] FreeZone Triad Benchtop Stoppering Tray Dryer and Lyophilizer has four valves to allow lyophilization in flasks simultaneously with samples in the tray dryer. The chamber pre-freezes samples on the shelves...

Automatic syringe pump.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] GENIE Plus precision syringe pump offers both infusion and withdrawal capability. It has the ability to synchronize with other equipment, connect to a computer or expand the system to create a network of infusion/...

Weigh trays.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] Made of antistatic, non-wetting polystyrene, these weigh trays are offered in 20, 100, and 330 ml sizes. Rounded inner corners and a smooth surface ensure sample removal with minimal loss. Flexible sides can be...

Stage accommodates plates, slides.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] NZ500CE NanoScanZ Piezo 500 micron stage (Prior Scientific, Inc.) is offered for deconvolution and 3D imaging techniques. A sub-angstrom resolution Piezo resistive sensor provides five nanometer repeatability and...

High pressure syringe pump.(Product News)
March 1, 2008... Model KDS 410 syringe pump is capable of pushing two, four, six, or 10 syringes simultaneously into reaction vessels. It works with syringe volumes from 10 [micro]L to 140 mL to provide accurate flow delivery from 1 nL/min to 145.5 mL/min. With...

Volumetric dosing syringe pump.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] The Atlas Syringe Pump offers an intuitive twist-and-click control that allows isolated operation. Alternatively, control via Atlas base or Atlas PC software allows intelligent, automated reagent addition and...

Rodent food/drink consumption evaluation.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] FooDrink, for evaluating consumption of food and drink by rodents, is compact. Weight transducer technology totally automates the monitoring process. It is minimally invasive and has a resolution of 50 rag. A...

Verification system for liquid handlers.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] MVS Multichannel Verification System provides NIST-traceable accuracy and precision data documenting the volume dispense performance of each channel of an automated liquid handler. An integration feature facilitates...

Dispensers and pumps.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] Products in the OEM Line of dispensers and pumps provide accuracy and chemical resistance. All units feature "no valve", one-moving part design. The line includes both fixed and variable displacement models. Standard...

Spill sensor.(Product News)
March 1, 2008... The OS250 system detects spills and leaks with as little as three drops of liquid. The system consists of a moisture sensing mat and control unit. The mat is made from a material developed for detecting liquid spills. It is connected to the...

C[O.sub.2] incubators.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] CB incubators feature an inner chamber with shelf supports that are formed as part of the chamber wall, increasing useful space and reducing cleaning requirements. Hot air sterilization temp is 180 C. A...

Lab glassware washer.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] PG 8527 glassware washer features an integrated conductivity meter in the water circuit for "contact-free sensing." Perfect Pure Sensor meter detects residue in wash water and can initiate a warning in the event that...

Targeted mutation mouse.(Product News)
March 1, 2008... [GRAPHIC OMITTED] The Hepatic Reductase Null (HRN) Mouse is offered for studies in ADME-Tox facilitating drug efficacy screening, lead selection, and lead optimization. This conditional, targeted knockout of Por (cytochrome P450 reductase)...

Mechanical pipettes.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] Proline Plus mechanical pipettes feature an ergonomic design, require reduced pipetting force, can be autoclaved, and offer UV-light resistance. Single-channel, multi-channel and fixed volume models offer dispense...

Bench-top protector.(Product News)
March 1, 2008... The Science Bench Top Protector features a polyethylene backing that creates an effective fluid barrier while providing excellent slip resistance. It resists harsh chemicals, quickly absorbs spills and retains its strength when wet. It offers...

Under-counter glassware washers.(Product News)
March 1, 2008... [ILLUSTRATION OMITTED] Available as either a free-standing or a mobile unit, Hotpack under- counter washers accommodate a range of specialty baskets in their upper and lower racks. Spindle-ready models, for cleaning narrow necked...

Universal wireless RS232 to USB transceiver.(Product News)
March 1, 2008... Model WRS232 provides a wireless interfaces to any RS232 device. By connecting the wireless transmitter to an RS232 device, the receiver module connects to a PC via USB interface. The wireless receiver can operate multiple wireless transmitter...

Mix solutions in tubes, plates.(Product News)
March 1, 2008... MixMate uses pre-set programs to mix samples in: 0.2 ml PCR to 2.0 ml micro test tubes; 96 and 384-well PCR plates; and shallow and deep-well plates at a maximum mixing frequency of up to 3,000 rpm. It provides controlled mixing of enzymatic...

Decontamination concepts for C[O.sub.2] incubators: a user's perspective.(EMERGING TECHNOLOGIES IN Life Science)
March 1, 2008... [FIGURE 1 OMITTED] Microbial contamination--caused by bacteria, bacterial spores, viruses, mycetozoa, yeast or other microorganisms--frequently presents a major risk in cell culture experiments. Because this contamination does not...

Custom peptide synthesis services.(EMERGING TECHNOLOGIES IN Life Science)
March 1, 2008... [ILLUSTRATION OMITTED] The company's custom peptide facility provides customers around the world with high quality peptides at competitive prices. Operating out of a modern peptide synthesis facility in the UK, the company quickly delivers...

Flow kit automates high-sensitivity genotoxicity studies.(EMERGING TECHNOLOGIES IN Life Science)
March 1, 2008... [ILLUSTRATION OMITTED] Offering a new flow-cytometric approach to genotoxicity testing, the gTox flow kit is a mouse micronuclei assay that evaluates a compound's ability to cause chromosomal damage. It detects micronuclei formed from...

Engineering solutions for diagnostics.(Best Practices)
March 1, 2008... As medicine moves closer to personalization and targeted therapy, the need for diagnostics that can rapidly and accurately predict and monitor the occurrence and progression of disease and drug treatments becomes critical. In an article...