Bioscience Technology articles from July 2004

Bioscience Technology archives from July 2004

HPLC-chip/MS technology.
July 1, 2004... Microfluidics-based technology is built upon a reusable polymer HPLC chip that replaces LC columns. Smaller than a credit card, the HPLC chip integrates the sample enrichment and separation capability of a nanoflow LC system with the intricate...

Antibody conjugation kit.
July 1, 2004... Qdot 655 Antibody Conjugation Kit enables the conjugation of antibodies of interest to Qdot 655 Nanocrystals. Quantum dot-antibody conjugates can be used in applications including immunohistochemistry, tissue staining, plate-based immunoassays,...

Electronic multichannel pipette.
July 1, 2004... New 12-channel Ovation BioNatural pipette is ergonomically designed and includes programmable functions that further minimize physical effort and save time. Four models dispense volumes from 0.5 to 850 [micro]l. Audible click indicates that...

CCD cameras.(Editor's Choice)
July 1, 2004... Sony Visual Imaging Products has introduced six IEEE 1394 high-resolution digital cameras well suited for bioscience applications. The XCD-SX and DFW-SX 910 camera series feature a l/2-inch progressive scan CCD while the XCD-X and DFW-X 710...

Freezer offers increased capacities.(Editor's Choice)
July 1, 2004... REVCO Super Insulation -86 C ultra-low temperature upright freezers incorporate thin wall insulation, a design change that increases interior volume. Upright cabinets are offered in 11, 25 and 32 cu/ft capacities. The 11 cu/ft model holds...

Digital imaging of multiple fluorochromes on Western blots.(Editor's Choice)
July 1, 2004... KODAK Image Station 2000MM Multimodal Imaging System offers selectable, multi-wavelength illumination allowing specific excitation and differential detection of multiple fluorochromes in gene expression assays such as Western blots. Using this...

Sequence analysis software.(Editor's Choice)
July 1, 2004... Causeway Version 1.1 sequence analysis environment increases the efficiency and usability of sequence annotation. It is designed with the intention that non-expert users are able to generate high quality, reliable analyses. Causeway runs as a...

Tube for cell counting.(Editor's Choice)
July 1, 2004... The PCV mini-tube, using 1 ml of sample, can quantify packed cell volume (PCV) in a matter of minutes. The mini-tube works by centrifuging cells down a precisely graduated capillary tube. Using a visual confirmation of volume, the user can very...

Automated digital microscope.(Editor's Choice)
July 1, 2004... Eclipse 90i microscope offers a USB interface for fast, direct external control. Digital Imaging Head, DIH-E, improves fluorescence performance with an integrated epifluorescence attachment that produces high signal-to-noise contrast ratios....

EIA for human XIAP.(Editor's Choice)
July 1, 2004... Immunoassay kit is offered for the quantitative determination of human XIAP in cell lysates. XIAP (X-linked inhibitor of Apoptosis) belongs to the IAP (inhibitors of apoptosis) family, which is characterized by one or more BIR (baculovirus IAP...

Instrument provides quick, durable tube labeling.(Tools & Techniques)
July 1, 2004... Joanne Campanile is a Senior Lab Technician who works with Deborah Driscoll, MD, in The Division of Human Genetics and Molecular Biology Laboratory at Children's Hospital of Philadelphia. The research in this lab includes analyzing the role of...

Micro-volume scale capture, purification and enrichment of proteins and antibodies.(Tools & Techniques)
July 1, 2004... Introduction The introduction of recombinant proteins that possess amino acid-tagged sites has resulted in a mechanism for many researchers to specifically extract proteins of interest from a mass of unwanted macromolecules in order to...

DNA, RNA purification workstation.(HTS Instrumentation and Assay Focus)
July 1, 2004... BioRobot EZ1 system provides fully automated purification of DNA and RNA from a range of clinically relevant samples, processing from 1-6 samples in as little as 15 minutes. Ready-to-run protocols on pre-programmed cards make simple. Pre-filled...

Reagent dispenser.(HTS Instrumentation and Assay Focus)
July 1, 2004... The Multidrop[R] Micro, the latest member of the Multidrop reagent dispenser family, is now optimized for dispensing protein containing solutions. This dispensing cassette also can be used for solutions such as 100% DMSO and viscous liquids, as...

MAPK-regulated transcription factor assay.(HTS Instrumentation and Assay Focus)
July 1, 2004... TransAM MAPK Family Kit makes quantitative measurement of MAPK-regulated transcription factors by independently screening ATF-2, AP-1 c-Jun, c-Myc, MEF2 and STAT1[alpha] DNA-binding activity. The ELISA-based format provides quantitative results...

High throughput platform for nanoliter pipetting.(HTS Instrumentation and Assay Focus)
July 1, 2004... High throughput option for TTP Labtech mosquito nanoliter liquid handling system increases capacity for compound dissolution applications such as compound-to-assay plate creation using a single step dilution, mosquito reproducibly pipettes...

Microplate luminometer.(HTS Instrumentation and Assay Focus)
July 1, 2004... Clarity microplate luminometer is offered for applications including reporter gene, ATP, DNA and reactive oxygen species assays and chemiluminescent immunoassays. Fast photon-counting ability and quality optics ensure sensitivity. Disposable...

Interchangeable sample block.(HTS Instrumentation and Assay Focus)
July 1, 2004... Moto Alpha[TM] interchangeable sample block, for use with any thermal cycler in the MJ Research DNA Engine[R] line, provides reliable plate positioning and sealing whether integrated into a robotic walk-away system or as a standalone unit. The...

High-speed dispenser.(HTS Instrumentation and Assay Focus)
July 1, 2004... WellMate high-speed, small-footprint, 8-channel fluid dispenser for 96 and 384 well micro-plates, features a height adjustable dispense head to accommodate dispensing to shallow and deep well plates and blocks. Low cost disposable...

Robot compatible 384 deep-well Plates.(HTS Instrumentation and Assay Focus)
July 1, 2004... NUNC 384 DeepWell natural polypropylene plates feature wells with a total volume of 252 [micro]l. Raised rims on the plates are facilitate heat or adhesive sealing. Polypropylene is heat-stable and chemical-resistant, making these plates useful...

Kinase assay toolboxes.(HTS Instrumentation and Assay Focus)
July 1, 2004... HitHunter[TM] kinase assay toolboxes combine all the components required to develop high-throughput screening assays for kinases based on fluorescence polarization, and provide the flexibility to optimize the buffer conditions and assay...

Biotin Label Transfer Kit.(HTS Instrumentation and Assay Focus)
July 1, 2004... ProFound Sulfo-SBED Biotin Label Transfer Kit for Western blot applications provides researchers performing protein: protein interaction studies in vitro method of discovering new interactions or confirming data from co-immunoprecipitation,...

Multimode detectors.(HTS Instrumentation and Assay Focus)
July 1, 2004... The DTX Series of detectors combines absorbance, fluorescence, and luminescence detection in one instrument. They operate as standalone instruments or can be integrated seamlessly with the company's Biomek[R] liquid handlers, and are ideal for...

TR-FRET kinase assays.(HTS Instrumentation and Assay Focus)
July 1, 2004... TR-FRET Kinase Assays The LanthaScreen assay platform is a time-resolved, resonance energy transfer (TR-FRET) detection technology used for high-throughput detection of kinases in drug discovery research, and measures protein-protein,...

High-throughput plate sealing.(HTS Instrumentation and Assay Focus)
July 1, 2004... High-Throughput Plate Sealing AutoSeal (Tomtec, Inc.) high-throughput microplate heat sealer integrates bi-directional stackers. The unit works with a variety of plate types and seal materials without the need for programming or using wedges to...

Homogenous assays.(HTS Instrumentation and Assay Focus)
July 1, 2004... HitHunter homogeneous, non-radioactive assays (Amersham Biosciences) come with clear protocols and can be read on both plate readers, and imaging platforms such as Amersham's LEADseeker Multimodality Imaging System. The product line features...

Expanded Tube Management System.(HTS Instrumentation and Assay Focus)
July 1, 2004... The capabilities of the Tube Management System (TubeStore[TM] TubeServer[TM] TekBench-SP[TM])have expanded to include additional tube storage formats, capacities up to 225,000 tubes per module, and inert environmental control through downstream...

Microplate washer.(HTS Instrumentation and Assay Focus)
July 1, 2004... Model DV993 is a flexible, fast and accurate microplate washing system featuring low residual volume. Up to 30 washing sequences can be preprogrammed and stored, and it comes available with an eight- or/and 12-channel manifold. The dispensing...

Liquid handling workstation.(HTS Instrumentation and Assay Focus)
July 1, 2004... New 96-tip head for the Hamilton Company MICROLAB STAR liquid handling workstation maximizes throughput and flexibility for sample preparation or assay automation. The unit combines the new 96 CORE head with up to 12 fully independent pipetting...

High content protein analysis system.(HTS Instrumentation and Assay Focus)
July 1, 2004... High Content Protein Analysis Systems The BD FACSArray[TM] bioanalyzer provides high-content analysis of proteins for work in cell biology, immunology, and drug discovery. This benchtop system is composed of an analyzer with a 96-well plate...

Personal archive DNA storage system.(HTS Instrumentation and Assay Focus)
July 1, 2004... High speed, room temperature DNA storage and retrieval platform, the GenVault Personal Archive storage system, facilitates on-site management of multiple DNA samples. The system uses GenPlate 384-well plates, which contain solid-state elements...

RNA isolations for RT-PCR analysis.(PCR & Related Technologies Focus)
July 1, 2004... RNA without genomicDNA contamination. Working with samples as small as I mg, or 100 cells, the rapid, phenol-free isolation procedure yields total RNA that is treated withDNase in an optimized reaction buffer. The DNase and divalent cations are...

Combination PCR kit.(PCR & Related Technologies Focus)
July 1, 2004... TripleMaster PCR product is suitable for long range PCR high fidelity PCR, and applications involving GC-rich or impure templates. The kit contains a Tuning Buffer to prevent long templates from breaking and to increase PCR sensitivity,...

Quantitative PCR assays.(PCR & Related Technologies Focus)
July 1, 2004... This DNA amplification system for real-time detection and quantification of specific eDNA and genomic DNA targets is compatible with all real-time PCR instruments and readily adapted for use in single or multiplex analyses. QZyme Assays measure...

DNA polymerase.(PCR & Related Technologies Focus)
July 1, 2004... Restorase DNA polymerase combines a long enzyme with a small amount of a DNA repair additive. The blend will initiate the repair and further amplification of damaged DNA templates greater that 800 bp. DNA can be damaged in a number of ways,...

DNA, RNA labeling.(PCR & Related Technologies Focus)
July 1, 2004... Six new kits are offeredchemical, non-radioactivelabeling of nucleic acids, including single-stranded, double-stranded, linear or super-coiled DNAg of target in a single reaction.Simple labeling protocols can be used to attach biotin,...

96 and 384 well PCR plates.(PCR & Related Technologies Focus)
July 1, 2004... Multiply PCR plates are made from thin-walled polypropylene to optimize temperature transfer from heating block to specimen. Test plates both without, half or full lateral skirt are available on request. Two new tape materials available for...

Real-Time PCR systems.(PCR & Related Technologies Focus)
July 1, 2004... The Applied Biosystems 7300 Real-Time PCR System and the Applied Biosystems 7500 Real Time PCR System combine thermal cycling, fluorescence detection, and application-specific software, offering an affordable solution for low-throughput genomic...

PCR system, reagent mix.(PCR & Related Technologies Focus)
July 1, 2004... PicoMaxx high fidelity PCR system is formulated with a blend of Taq and Pfu DNA polymerases and ArchaeMaxx polymerase-enhancing factor. Along with an optimized buffer, this formulation enables the detection of low-copy-number targets in complex...

PCR purification system.(PCR & Related Technologies Focus)
July 1, 2004... AMPure[R] is a SPRI[TM]-based PCR purification system that efficiently purifies amplicons as small as 100 bp. PCR amplicons are selectively bound to polystyrene paramagnetic microparticles, thus eliminating the high background and lower yields...

PCR plates.(PCR & Related Technologies Focus)
July 1, 2004... Greiner Bio-One offers 96 and 384 well polypropylene and traditional 96 well polycarbonate PCR plates. The plates have excellent heat exchange properties and are guaranteed DNase/RNase free and non-pyrogenic. Several skirt options are available...

PCR Workstations with microscope compatibility.(PCR & Related Technologies Focus)
July 1, 2004... The microscope-compatible workstation can now accommodate both single- and dual-ocular microscopes. This PCR Workstation[TM] protects against PCR contamination in two ways. UV irradiation of the working area prior to use blocks replication of...

Engineered PCR enzyme.(PCR & Related Technologies Focus)
July 1, 2004... Phusion High-Fidelity DNA polymerase incorporates a patented DNA-binding element which dramatically increases polymerase processivity. Phusion polymerase provides fidelity, high yields per unit, and short reaction times for long targets (1 kb...

Ex Taq Polymerase.(PCR & Related Technologies Focus)
July 1, 2004... Real-time PCR offers a quantitative method for viral and bacterial pathogen detection, measurement of gene expression, and mutation detection. Takara's Real Time Ex Taq Polymerase, a version of Ex Taq polymerase formulated for real time PCR,...

DNA polymerase.(PCR & Related Technologies Focus)
July 1, 2004... EPICENTRE's MasterAmp Tth DNA polymerase contains both reverse transcriptase and DNA-dependent DNA polymerase activities and is offered for single-tube RT-PCR. Reverse transcription using the product can be performed at temperatures up to 60 C...

PCR plastics.(PCR & Related Technologies Focus)
July 1, 2004... Plastic disposables for PCR include 0.2 ml and 0.5 ml tubes; tube and cap strips in a variety of colors; non-skirted and semi-skirted 96-well plates; skirted 384-well plates; sealing films; and more. Cover mats substantially reduce evaporation,...

PCR Workstation.(PCR & Related Technologies Focus)
July 1, 2004... Sterilaire UV PCR Workstation brings together UV light and antimicrobial stainless steel to create a protective environment against PCR contamination. The unit's chamber can be decontaminated between procedures with high intensity shortwave 254...

UV crosslinker eliminates PCR contamination.(PCR & Related Technologies Focus)
July 1, 2004... Spectrolinker[TM] XL-1000 UV crosslinker covalently binds nucleic acids to membranes in less than 30 seconds. The unit is offered for eliminating PCR contamination, crosslinking DNA and RNA, nicking ethidium-bromide stained DNA, gene mapping,...

Server and workstation modules.(PCR & Related Technologies Focus)
July 1, 2004... The THEQ LifeCycler series' combination of server and workstation modules and virtual networking capabilities allow for individual PCR workload definition with efficient centralized operation. This enables customers to implement their own...

Identify differentially expressed genes.(PCR & Related Technologies Focus)
July 1, 2004... GeneFishing Technology offers a unique approach for identifying only authentic Differentially Expressed Genes (DEGs) in two or more nucleic acid samples. This technology improves specificity of PCR amplification, enabling researchers to find...

Multichamber array.(Array Technologies Focus)
July 1, 2004... Conduct hybs, washes, detections and other processes at up to 16 experiments per slide, simultaneously treating the group as a single working unit. Four, "16-array" slides fit into a tray that allows robotic systems to process them. Contact...

Three-dimensional microarray surface.(Array Technologies Focus)
July 1, 2004... High gain microarray surface is based on anisotropic etching of a glass surface. The etching process uses photolithographic techniques to create a regular 3D pattern in the surface. Within each microfeature, the etching produces a...

Epoxide-Coated Slides.(Array Technologies Focus)
July 1, 2004... As the progression from cDNA arrays to oligos continues, Coming offers a substrate for covalent attachment of short oligonucleotides with reagents for printing, hybridization and array washing. Pronto Universal Hybridization Kits are optimized...

Human gene silencing libraries.(Array Technologies Focus)
July 1, 2004... Dharmacon, Inc., has expanded its siARRAY Small Interfering RNA (siRNA) library offering. The company has also introduced a whole human genome library containing over 100,000 gene-silencing reagents targeting more than 22,000 unique human genes...

Ceramic materials for life science research.(Array Technologies Focus)
July 1, 2004... The company offers a range of ceramic materials and coatings for microarray slides. With their chemical inertness, resistance to protein binding, and optical properties, the ceramic materials and coatings provide an ideal environment for...

Microarray labeling.(Array Technologies Focus)
July 1, 2004... Label IT Arra[y.sup.Biotin] Kits (Mirus Corp.) offer a single color, chemical labeling method optimized for use in microarray applications. Substitute this simple method for covalent mRNA, cDNA and cRNA labeling directly into a current...

Custom arrays.(Array Technologies Focus)
July 1, 2004... MetriGenix, Inc is offering custom arrays for gene expression analysis on their MGX 4D Array System. Arrays can be designed for any organism. Array content, design and density can be customized, and can contain from 50 to 384 probes....

RNA amplification, labeling.(Array Technologies Focus)
July 1, 2004... Ovation Biotin RNA Amplification and Labeling System is offered for use on Affymetrix GeneChip arrays. It is validated for reproducibility, fidelity, and sensitivity with GeneChip arrays, using only 5ng of total RNA. The Ovation Aminoallyl RNA...

Human Whole Genome Bioarray.(Array Technologies Focus)
July 1, 2004... Amersham Biosciences has added a Human Whole Genome Bioarray to its CodeLink product range. With 54,841 gene targets, the new chip offers high content, the majority of which has been functionally validated. Consolidating genome-wide expression...

Rat Gene array.(Array Technologies Focus)
July 1, 2004... Rat Gene BioGridArray (BGA) facilitates gene-expression studies of toxicity. BGA was developed by choosing genes that have been found to be regulated in response to stress or exposure to toxicants according to publicly available data. To...

Universal slide kits.(Array Technologies Focus)
July 1, 2004... Ez-rays universal microarray surface can be used with cDNA probes, oligonucleotide probes (unmodified, amine-modified, or Acrydite modified), and proteins. The slides provide high signal intensity, low background, and effective reproducibility...

Protein Microarrayer.(Array Technologies Focus)
July 1, 2004... The NanoPrint Protein Edition High Throughput Microarrayer includes everything needed to manufacture protein microarrays. The product includes a Stealth 48 Micro Spotting Device (with extended collars); multi-station wash, dry station and...

Microarray slides.(Array Technologies Focus)
July 1, 2004... Vivid [TM] microarray slides are constructed of a glass base with a membrane printing area. The use of membrane slides as a microarray substrate facilitates high binding and simple immobilization methods. Vivid slides offer high signal to noise...

Biomarker Chips.(Array Technologies Focus)
July 1, 2004... Serum Biomarker Chips facilitate profiling of serum biomarkers and discrimination of stages of disease progression. Detection of over-and under-abundant serum biomarkers has value in cancer research. Proteomics researchers can profile and...

Electronic microarray, a silicon chip, for SNPs, STRs, mutation analysis.(Array Technologies Focus)
July 1, 2004... Electronic microarrays from Nanogen contain 100 test sites laid out in a geometric grid. Each test site on the NanoChip array can be controlled electronically from the NanoChip Workstation's on-board computer. A permeation layer coated on the...

Non-contact dispensing of nanoliter.(Array Technologies Focus)
July 1, 2004... Volumes Piezorray non-contact microdispensing system is designed specifically for pipetting sub-nanoliter volumes to dense arrays. Liquid volumes are controlled by a piezo-electric tip that dispenses reproducible picoliter volume droplets. The...

RNA Amplification for array analysis.(Array Technologies Focus)
July 1, 2004... MessageAmp II aRNA Amplification Kit incorporates the newly engineered ArrayScript M-MLV RT to maximize yields of full length cDNA. The kit selects and amplifies mRNA from as little as 100 ng of input RNA in a single round of amplification for...

Murine Cytokine Biochip.(Array Technologies Focus)
July 1, 2004... Murine Cytokine Biochip enables multiplexed analysis of thirty mouse cytokines, chemokines and growth factors using minimal sample volumes. The biochip provides access to quantitative parallel data on cytokine activity, as well as to...

HPLC-chip/MS technology.(Array Technologies Focus)
July 1, 2004... Microfluidics-based technology for liquid chromatography/mass spectrometry (LC/MS) (Agilent Technologies, Inc.), is built upon a reusable polymer HPLC chip that replaces LC columns. Smaller than a credit card, the HPLC chip integrates the...

Three-color array scanner.(Array Technologies Focus)
July 1, 2004... Genetix has announced a 3-colour aQuire dual-laser microarray scanner for detection of GFP, fluorescein and a range of other fluorophores, providing verstatility for imaging DNA, protein, cell and tissue arrays. The standard aQuire scanner is...

Array building kits.(Array Technologies Focus)
July 1, 2004... Thiol-based Functionalization Kits include a choice of thiol-based chemicals, gold-coated glass slides or cover-slips, as well as an easy-to-follow protocol. The kits offer an alternative to purchasing custom-synthesized chemicals in bulk and...

Grape genome oligo set.(Array Technologies Focus)
July 1, 2004... Grape (Vitis vinifera) Array-Ready Oligo Set contains 14,562, 70-mer probes representing grape gene transcripts, and is a tool for microarray analysis of grape gene expression. Each probe is melting-temperature normalized and includes a 5'...

Polymer and glass microarray slides.(Array Technologies Focus)
July 1, 2004... NUNC has introduced a range of microarray slides and accessories. Slides are made with polymer or glass and are available with a number of different surface chemistries optimized for nucleic acid, protein, cell and tissue applications. Polymer...

Oligonucleotide slide.(Array Technologies Focus)
July 1, 2004... Nexterion Slide E provides an active coating chemistry for the immobilization of oligonucleotides. The slide's active layer is made up of reactive epoxy groups that form an immediate and irreversible covalent bond with all the probe's...

Arrays for SNP genotyping studies.(Array Technologies Focus)
July 1, 2004... GeneChip Mapping 10K 2.0 Array and GeneChip Mapping 100K Array Set from Affymetrix provide an affordable array for genotyping for over 10,000 SNPs and a new information-rich array set for genotyping over 100,000 SNPs. The Mapping 10K Array has...

Quantitated PCR control DNA for H. pylori.(Tools & Techniques)
July 1, 2004... Introduction To aid research investigations on the putative role of H. pylori infection in the etiopathogenesis of gastric ulcer and/or gastric adenocarcinoma/lymphoma, Advanced Biotechnologies Inc (ABI) offers H. pylori (Strain J 99:...

Biocompatible in-line check valves.(Liquid Handling Focus)
July 1, 2004... Upchurch Scientific nonmetallic, biocompatible in-line check valves has been expanded. These PEEK polymer inlet and outlet check valves offer backflow protection, biocompatibility and chemical resistance. Spring-less design results in low...

Electronic multichannel pipette.(Liquid Handling Focus)
July 1, 2004... New 12 channel Ovation BioNatural pipettes share the ergonomic design features as single channel models, and include a number of new electronic programmable functions to further minimize physical effort and save time. Four 12-channel models...

Programmable pipettor.(Liquid Handling Focus)
July 1, 2004... The Drummond Pipet-Aid Elite[TM] facilitates fast, accurate, pipetting and allows easy, comfortable operation. The lightweight Elite features intuitive user-friendly programming functions and "Easy Touch" buttons. Using a 10 ml pipet, it is...

Mechanical pipettors.(Liquid Handling Focus)
July 1, 2004... Mechanical pipettors mLINE (Biohit) pipettors feature low pipetting and tip ejection forces, light weight and ergonomic design. The units can be completely autoclaved, and tip cone filters prevent the contamination of the pipettor and samples....

Benchtop dispensing pump.(Liquid Handling Focus)
July 1, 2004... Peristaltic dispensing pump 323Dz (Watson-Marlow Bredel) incorporates a flip-top pump head for simple tube loading. The unit is offered for applications such as metering, dosing and the scale transfer of live cell cultures, nutrients and...

Electronic pipettes.(Liquid Handling Focus)
July 1, 2004... Eppendorf Research Pro single and multi-channel pipettes offer a variety of programmable application parameters. Display screen is set at a 45[degrees] angle for easy reference during use. All buttons and controls are large and accessible....

Compound reformatter.(Liquid Handling Focus)
July 1, 2004... Labeyte[R] Echo 550 compound reformatter performs direct microplate-to-microplate transfers droplets down to 5 nl (CV 5-50 nl Use InfoLINK 4G1389 or Call 800-287-0633 [ILLUSTRATION OMITTED]

Adjustable volume pipettors.(Liquid Handling Focus)
July 1, 2004... mLINE pipettors reduce muscle stress, which reduces fatigue and provides more reproducible results. Proprietary tips are not required. Spring-assisted Optiload System limits the force that can be used during tip application. Pipet tips are...