Bioscience Technology articles from January 2006

Bioscience Technology archives from January 2006

The beauty of cell-based assays.(analytical methods)(Editorial)
January 1, 2006... The term cell-based assays (CBAs) can be read as shorthand for a voluminous range of products with uses in many and diverse methods. Contributing Editor Angelo DePalma has uncovered a number of applications that incorporate, or in some cases...

Human cells develop resistance to RNAi.
January 1, 2006... Researchers have discovered that RNA interference (RNAi), a technology that uses a naturally occurring process to silence genes, may stop working in some cells after a period of time. RNAi is used to study gene function and has potential for...

Image contest recognizes imaging work.
January 1, 2006... Media Cybernetics, an analytical imaging software provider, has announced the 2006 "Imaging in Action" Image Contest, the fifth year for the contest in which the company recognizes the work of their imaging software users. The competition...

MicroRNA-adapted short hairpin RNA library helps.
January 1, 2006... Four cancer centers have adopted Open Biosystems, Inc.'s short hairpin RNA (shRNAmir) technology to aid in the identification of cancer treatment options. Duke University, the National Institutes of Health's National Cancer Institute, Lee...

Image of rat's eye takes first place in BioScapes Competition.(2005 Olympus BioScapes International Digital Imaging Competition)(Brief Article)
January 1, 2006... If the key to the inner self is visible by looking deeply into someone's eyes, rats must be among nature's most glorious creatures--for a stunning, brilliantly hued and richly patterned photograph showing the inside of an aging rat's eye has...

Bacterial screening, plasmid DNA prep.(JANUARY'S TECHNOLOGY)
January 1, 2006... OriMaster screens bacterial colonies and prepares plasmid DNA for cycle sequencing, site determination, restriction mapping and other enzymatic reactions. The product uses an in vitro amplification method that starts from a single bacterial...

Nucleic acid amplification, analysis.(JANUARY'S TECHNOLOGY)
January 1, 2006... The Evocycler provides thermal cycling and results analysis. Each assay generates a Gel Photo, similar to the familiar electrophoresis run; melt curve analysis is performed by the instrument at the end of the run, and the analysis is displayed...

Desktop DNA sample storage.(JANUARY'S TECHNOLOGY)
January 1, 2006... GenVault Corp. (Carlsbad, CA) has announced the Desktop Archive, a small, stand-alone storage module that holds up to one hundred GenPlates. A GenPlate is a 384-well plate system for room temperature dry state storage of DNA that eliminates the...

Benchtop cellular analysis system.(JANUARY'S TECHNOLOGY)
January 1, 2006... EasyCyte Mini cell analyzer combines multi-color analysis and absolute cell counting. Microcapillary technology provides small sample volume requirements. Blue laser analysis expands the selection of fluorescent dyes available to users. Turnkey...

Multi-Sensor Platform chip for biosensor applications.(JANUARY'S TECHNOLOGY)
January 1, 2006... Many life science applications, such as PCR-on-chip, require precise temperature sensing and heating. The Multi-Sensor-Platform chip from Heraeus Sensor Technology combines several platinum thin film structures, such as temperature sensors,...

Zero Drift microscope for prolonged time-lapse imaging.(JANUARY'S TECHNOLOGY)
January 1, 2006... The Olympus IX81-ZDC Zero Drift microscope system provides autofocus imaging for time-lapse experiments using inverted microscopes. The fully integrated unit was designed specifically for prolonged time-lapse studies, and uses a Class 1 785-nm...

RNAi expression vector kits.(JANUARY'S TECHNOLOGY)
January 1, 2006... BLOCK-iT Pol II miR RNAi expression vector kits combine artificial miRNAs and the tissue-specific options of pol II promoters with the traditional advantages of RNAi vectors. In addition to stable and/or regulated expression and viral delivery...

Cell-based assays: exploiting an exquisite middle ground.
January 1, 2006... One would be hard-pressed to identify a significant event in the life of an organism that does not manifest itself in some way inside cells. Because they comprise the smallest living units, cells offer an accessible window for studying...

Solid phase extraction with the Caliper Sciclone i1000.
January 1, 2006... Introduction Solid-phase extraction (SPE) has proven to be an effective sample cleanup technique in preparation for instrumental analysis. However, the process can often be very labor-intensive and error-prone. Automating sample...

Compact centrifuge.(LABORATORY EQUIPMENT)
January 1, 2006... The Z100 A compact centrifuge is supplied with a six place rotor for tubes with capacities of 10 to 15 ml, accepts smaller tubes with the use of adapters, and accommodates all common blood collection tubes. Speed is variable from 1,000 to 4,000...

Reverse osmosis water.(LABORATORY EQUIPMENT)
January 1, 2006... RiOs 3 water purification system is offered for laboratories that require up to 30 liters/day of high quality pure water from tap. The system is suitable for general non-critical applications such as manual cleaning/rinsing and buffer...

Water chiller.(LABORATORY EQUIPMENT)
January 1, 2006... The FE1100 chiller cools water nearly silently. Compact design allows the unit to be located directly under a lab bench. Temperature is displayed on bright LED's and offers a set point of anywhere between +5 and +30 C. The air-cooled FE1100 is...

Surgical bone drill.(LABORATORY EQUIPMENT)
January 1, 2006... Compact bone drill has a tiny, high speed DC motor in the remote hand piece, eliminating drive cables and giving the user better control. For hands-free operation, power is controlled by a panel switch, or with a foot switch. The separate power...

In-line filter.(LABORATORY EQUIPMENT)
January 1, 2006... Upchurch Scientific offers a high-pressure inline filter for semi-prep and preparative applications. This filter will prolong the life of instrument components and improve results. With its 5/16-24 threads, it can easily be connected to 1/8" OD...

Micro C[O.sub.2] incubator.(LABORATORY EQUIPMENT)
January 1, 2006... The Innova CO-14 incubator is just under 17 inches tall, and is offered specifically for isolating sensitive samples. Under 13" wide, the unit readily allows maintenance of sample separation of sensitive cultures or in-vitro fertilized eggs....

Benchtop biohazard storage.(LABORATORY EQUIPMENT)
January 1, 2006... Terminal Brand Biohazard BenchTop Keepers collect contaminated non-sharp waste without having to make unnecessary trips to your central biohazard container. Plastic lined to avoid leaking, the products keep work areas neat and clean....

Micro-homogenization.(LABORATORY EQUIPMENT)
January 1, 2006... The PRO200 homogenizer is offered for processing in 0.5, 1.5 or 2.2 ml micro-tubes. The standard micro-homogenizing package, including the homogenizer and a 5 x 75 mm generator, allows volumes as small as 0.03 ml to be processed in seconds....

Centrifuge with interchangeable rotors.(LABORATORY EQUIPMENT)
January 1, 2006... The Combo V24 centrifuge provides both test tube and hematocrit separations with one unit. Tools are not required to change out the rotors. The instrument reaches speeds up to 12,000 rpm on the high speed setting and can hold up to 24 test...

LED transilluminator.(LABORATORY EQUIPMENT)
January 1, 2006... Spectroline BlueGlo transilluminator uses employs LED technology to illuminate fluorescently stained DNA, RNA, proteins and other biological samples without the risk of photonicking or additional generated heat. The blue light excites...

Analytical balances.(LABORATORY EQUIPMENT)
January 1, 2006... Excellence Plus XP balance features SmartSens, an option that allows hands-free use; SmartGrid, a grid-style weighing pan; and SmartScreen, a color touch-screen display allowing full compliance options. Hands-free operation allows the user...

Ductless fume hoods.(LABORATORY EQUIPMENT)
January 1, 2006... Purair ductless fume hoods meet OSHA, ANSI and other relevant standards. Completely portable and self contained, the hoods protect personnel using HEPA filters and activated carbon filtration techniques. Six models offer face velocities of 100...

Vacuum concentrator.(LABORATORY EQUIPMENT)
January 1, 2006... The miVac Speed Trap vacuum concentration system features a novel cooled condenser coil that operates in a novel way. Cold condenser coils are suspended directly in the vapor path, solvent vapors condense directly on the coils and run off into...

Programmable pipettor.(LABORATORY EQUIPMENT)
January 1, 2006... Programmable Pipet-Aid Elite 400, the latest addition to Drummond Scientific Company's Pipet-Aid line of hand-held pipettors, features user-friendly programming functions to enable quick and easy volume setting based on pipet size. The unit...

Heating, cooling circulators.(LABORATORY EQUIPMENT)
January 1, 2006... Lauda Proline bench-top heating/ cooling circulators provide temperature control from -90 to 300 C. A detachable control panel provides effective control of functions from up to 150 feet away from the bath. Unit features include a Windows-based...

New cryostat.(LABORATORY EQUIPMENT)
January 1, 2006... Shandon Cryotome FE/FSE cyrostats have been made 7" taller, to allow comfortable operation standing or seated. For the seated operator, a footrest adjustable to three positions provides additional support. Rounded edges provide support and ease...

Valveless dispensers, metering pumps.(LABORATORY EQUIPMENT)
January 1, 2006... Positive displacement VMP dispensing system features a programmable dual stepper design that independently controls stroke rate and displacement. Utilizing the CeramPump no-valve design, the system features a Touch Screen Interface (TSI) that...

Lab worktables.(LABORATORY EQUIPMENT)
January 1, 2006... MetroMax worktables address a range of lab requirements and resist corrosion. Built from polymers that include Microban antimicrobial product protection, the tables are modular, and available in steel and TRESPA phenolic resin in black or gray....

Programmable rotary microtome.(LABORATORY EQUIPMENT)
January 1, 2006... The RM2265 fully motorized and programmable rotary microtome offers user safety, ergonomic and performance reliability. Accessible controls reduce repetitive motions. Accessories, such as an ergonomically integrated section waste tray and...

Deep-well compact baths.(LABORATORY EQUIPMENT)
January 1, 2006... Constant-temperature fluid baths are offered for the calibration of thermometers and temperature sensors. The compact baths are 18" deep, and accommodate liquid-in-glass (LIG) thermometers, SPRTS and other long-stem thermometers. They do so...

Filtered pipette tips.(LABWARE)
January 1, 2006... Finntip filter pipette tips provide protection against contamination for both sample and pipette. The non-sealing filter prevents the transfer of aerosols from tip to pipette and vice versa, ensuring the integrity of any pipetting function....

Cell Scrapers.(LABWARE)
January 1, 2006... BD Falcon Cell Scrapers provide accessibility to growth surfaces in a variety of cell culture vessels. Pivoting blade provides the correct angle for removal of cells from the entire growth surface. The flexible handle is textured for a firm...

Streptavidin coated microplates.(LABWARE)
January 1, 2006... Streptavidin coated microplates are available in 96- and 384-well formats. Users can utilize the high affinity Streptavidin/ Biotin bond (1 SA:4 Biotin molecules) to enhance biotinylated protein, nucleic acid and antigen-antibody (all easily...

Extended length pipette tips.(LABWARE)
January 1, 2006... Biomek P30XL Tips, for use with Beckman Coulter, Inc.'s AP384-multichannel pipetting heads, are a full 43 mm long and reach the bottom of deep 384-well labware. The tips retrieve samples on Beckman Coulter's Biomek FX and NX and Multimek liquid...

2-D or linear, compact bar code reader.(LABWARE)
January 1, 2006... The VisionMate One Wireless compact, 2-D or linear bar code reader employs Bluetooth wireless technology. Suited for satellite locations or fieldwork, the versatile single-tube reader provides secure data transmission between the reader and a...

Box holds pipette tips.(LABWARE)
January 1, 2006... The Tip SystemBox with hinged lid combinwa with Sarstedt's various 96-tip packs to provide convenient and stable pipetting station. Manufactured from high-grade polypropylene, the box is reusable and designed for multiple applications such as...

384-shallow-well plates.(LABWARE)
January 1, 2006... Nunc's 384 shallow-well, standard-height plates are offered for applications assays and small volume storage. Polypropylene composition resists chemicals. The plates include a round-bottom well design for optimal sample retrieval, and an...

HDPE reagent bottles.(LABWARE)
January 1, 2006... HDPE reagent bottles provide secure storage and transport of reagents. Narrow and wide-neck bottles are offered in natural or opaque white. Narrow neck reagent bottles in 500 ml, 1 and 2.5 liter volumes are provided for safe storage and...

Automated Bar Code Reader.(LABWARE)
January 1, 2006... Biomek Automated Tube Bar Code Reader (ATBCR) (Beckman Coulter, Fullerton, CA) allows the processing of open-top, tube-based samples and controls. Integrated with Beckman Coulter's Biomek Software, the ATBCR establishes positive I.D. and...

Small solenoid valve.(LABWARE)
January 1, 2006... Ultra-miniature, magnetically-latched solenoid valves in the 120 series weigh just 300 mg and require only a momentary 1-ms pulse to switch the state (5 VDC to open, -5 VDC to close). Suited for compact battery powered pneumatic applications...

Membrane-bottom filter plates.(LABWARE)
January 1, 2006... Filter plates in 96-well and 384-well formats bring speed and throughput to sample filtration on a microliter to milliliter scale. Membrane-bottom individual sample wells or chambers have separate high-strength single or dual filter membranes...

Linear pipettor stand.(LABWARE)
January 1, 2006... Linear stand is suited for the safe storage of mechanical and electronic pipettors. The skid-proof unit works with Biohit pipettors, as well as most other major brands. * Biohit Inc. 800-922-0784 www.biohit.com [ILLUSTRATION...

RNA Isolation Kit.(RNA RESEARCH PRODUCTS)
January 1, 2006... PureLink FFPE RNA Isolation Kit provides a simple method for isolating total RNA from formalin-fixed paraffin-embedded (FFPE) samples. A heating procedure replaces protocols that use toxic organic solvents for deparaffinization and requires...

DualChip DNA Microarray.(RNA RESEARCH PRODUCTS)
January 1, 2006... DualChip Microarray Systems are offered for rapid gene expression analysis and pathway identifications in toxicology, neuroscience, signal transduction, and research on aging using human or rat models. Xmer technology-based probes contain...

Acrylamide buffer blend.(RNA RESEARCH PRODUCTS)
January 1, 2006... ElectroSNAP acrylamide buffer blend is mainly used in the preparation of polyacrylamide gels of small size DNA and RNA, (>20 bp), which can then be used in routine analysis of PCR products rot monitoring nuclease and ligase reactions and for...

Drug, disease mediation assay.(RNA RESEARCH PRODUCTS)
January 1, 2006... ArrayPlate qNPA technology facilitates measurement of how drugs act and diseases are mediated at the level of whole cells, tissues, or organisms. The ArrayPlate technology platform does not require extraction, purification or amplification of...

High throughput Electroporation.(RNA RESEARCH PRODUCTS)
January 1, 2006... The HT Electroporation System offers a 96 Well Electroporation Plate and the Plate Handler that can be used to design and optimize electroporation experiments and be used to deliver siRNA and DNA expression vectors into mammalian ceils. The...

MicroRNA Assays.(RNA RESEARCH PRODUCTS)
January 1, 2006... TaqMan nficroRNA Assays are offered for the detection and quantitation of mature human microRNA (miRNA) expression levels, miRNAs are a recently discovered class of small RNA molecules known to play a powerful regulatory role in cell...

Vectors for Gene Knockout.(RNA RESEARCH PRODUCTS)
January 1, 2006... TargeTron Vectors, for use with the TargeTron Gene Knockout System (Sigma-Aldrich, St. Louis, MO), enhance the capabilities and increase the flexibility of the system, providing an efficient method for knockout of multiple genes in prokaryotic...

Gel cartridge kit.(RNA RESEARCH PRODUCTS)
January 1, 2006... GCK-RNA QC (Quality Control) gel cartridge kit, for use with the eGene HDA-GT12 Genetic Analyzer, can be used to check the quality of total RNA, poly A RNA, cRNA, fragmented RNA and fragmented cDNA prior to performing Northern blots, real-time...

One-step RT-PCR kits for real-time, multiplex analysis.(RNA RESEARCH PRODUCTS)
January 1, 2006... QuantiTect Multiplex RT-PCR Kits provide reliable quantitation of up to four RNA targets in a tube or well without optimization steps. Designed for gene expression analysis, the kits provide accurate quantification of the expression of target...

RNase-resistant RNA aptamers.(RNA RESEARCH PRODUCTS)
January 1, 2006... DuraScribe T7 and SP6 transcription kits produce RNA transcripts (DuraScript RNA) that are completely resistant to RNase A. DuraScribe T7 and SP6 RNA polymerases, provided in the kits, are mutant forms of T7 and SP6 RNA polymerases that...

Small RNA labeling kit.(RNA RESEARCH PRODUCTS)
January 1, 2006... Small RNA labeling kit exploits ULS labeling technology, directly labeling any and all sizes of naturally occurring nucleic acids without the need of enzymes. Due to their small size, small RNA molecules prove very difficult to label via the...

RNA amplification method.(RNA RESEARCH PRODUCTS)
January 1, 2006... MessageAmp II-Biotin Enhanced Kit uses the T7 linear amplification method commonly referred to as the Eberwine method (Van Gelder et al. 1990) to amplify RNA from a total or mRNA sample in a way that most accurately represents the initial mRNA...

Gene expression reagents.(NEW Technology)
January 1, 2006... Applied Biosystems has launched Pourer SYBR Green PCR Master Mix, a line of reagents for real-time PCR gene expression applications. SYBR Green dye binds to any double stranded DNA molecule, offering a flexible and easy to use labeling method...

Raman, notch filters.(NEW Technology)
January 1, 2006... RazorEdge Raman filters (Semrock, Inc.) are now available for 355 nm (tripled Nd: YAG laser) and 363.8 nm (Argon-ion laser). Neat to the Raman filter line, which spans the range of laser wavelengths from 325 to 1064 nm, these steep edge-filters...

Quantitative HPLC analysis of lipids: the charged aerosol detector detected common lipids such as triacylglycerols, cholesterol esters, and free sterols to a minimum limit of detection of about 1 nanogram per injection. The mass to peak area ratio was nearly linear from about 1 nanogram to 10 micrograms per injection.(APPLICATION Note)
January 1, 2006... A recent study by Dr. Robert A. Moreau, of the Eastern Regional Research Center of the Agricultural Research Service, USDA, evaluated a charged aerosol detector (CAD), a new type of liquid chromatography detector, (1) with several normal phase...

Bar code reader.(NEW Technology)
January 1, 2006... Biomek Fly-By bar code reader provides positive sample identification and microplate tracking during sample processing on Beckman Coulter Biomek workstations. This reader enables the tracking of a sample as it moves through the process,...

Automation platform.(NEW Technology)
January 1, 2006... SuSy automatic workbench enables execution of a workflow to test a large number of compounds in parallel. The reactor is based on the plate format for either 24, 48 or 96 different compounds or different testing parameters. Tools for...

Data Analysis software tool.(NEW Technology)
January 1, 2006... DeCyder Extended Data Analysis (EDA) version 1.0, for proteomics research, enables combined analysis of different data sets and facilitates biological interpretation of results through public and local database retrieval. The tool adds value to...

Human cancer research products.(NEW Technology)
January 1, 2006... Human clinical specimen derivatives and high throughput protein and tissue microarrays are assembled in a comprehensive collection of ready-to-use human protein extracts. These human tissue lysates are suitable for use in a range of...

PCR Arrays.(NEW Technology)
January 1, 2006... SuperArray Bioscience has released a PCR-based technique for profiling the expression of a focused panel of genes. These PCR Arrays bring routine expression profiling to researchers who prefer PCR-based methods over hybridization-based...

Microplate handler.(NEW Technology)
January 1, 2006... Bio-Tek Instruments, Inc. offers the Caliper Life Sciences' Twister II microplate handler to their line of Bio-Stack automated systems. BioStack Twister II interfaces to one or more Bio-Tek plate readers, washers or liquid handling systems,...

Array for systematic biology.(NEW Technology)
January 1, 2006... Pre-made GFC-Arrays are offered that are based upon a broad range of therapeutic and structural motifs (protein kinases, transmembrane, pharmaceutically tractable genome, etc.) As an example, the company represents a simple selection of the...

Microplate incubator stirrer.(NEW Technology)
January 1, 2006... DV994 incubator features a 4-plate rack holder for continuous or preset operation. Electronic stirring speed adjustment provides 300-1500 rpm orbital motion. Temperature range is ambient to 50 C. Safety sensors disable stirring when the cover...

High-throughput gene expression: analysis of Arabidopsis thaliana using quantitative RT-PCR: quantitative RT-PCR has emerged into the mainstream for quantification of gene expression, largely due to development of real-time RT-PCR. RT-PCR is simple to perform, sensitive, and suitable for quantification of rare transcripts or small changes in gene expression.(reverse transcript-polymerase chain reaction)
January 1, 2006... Regulation of gene expression at the level of transcription controls many biologically important processes. Thus, investigations analyzing gene expression are fundamental for understanding cell growth and development, as well as response to...

Macroreticular solid supported reagents.(NEW Technology)
January 1, 2006... A series of high specification, macroreticular (MR) solid supported reagents are part of the StratoSpheres scavenger resin product range. These reagents are based on a large pore volume, high load MR base resin. A large bead size provide fast...

Dialysis, electroelution system.(NEW Technology)
January 1, 2006... D-Tube Dialyzers dialyze sample volumes from 10-3000 [micro]l. The screw-cap tubes are integrated with a regenerated cellulose membrane, so they are easy to load and unload. They can be also used to electroelute DNA, RNA, protein or proteinDNA...

Australian-sourced bovine albumin.(NEW Technology)
January 1, 2006... Probumin Plus Albumin is manufactured from Australian-sourced material, a country classified as BSE-free (Bovine Spongiform Encephalopathy-free). The latest offering in Celliance Corporation's line of 30 bovine albumin products allows...

Chemical Inventory System.(NEW Technology)
January 1, 2006... Users of the CISPro CIS Chemical Inventory System can now leverage ChemGold2, which delivers extensive MSDS (materials safety data sheet) information via the Internet, enabling CISPro Web users to subscribe and link to a large database of...

Lab informatics software.(NEW Technology)
January 1, 2006... TERANODE Reagent Production software supports reagent production control, QA, and reporting in the synthesis of organic and inorganic compounds, for peptide synthesis and protein expression research, DNA and RNA research, and in the development...

Dual NMR CryoProbes.(NEW Technology)
January 1, 2006... The DCH CryoProbes produce a [13.sup]C spectrum in only a few minutes, enabling the acquisition of up to 250 spectra per day for high-throughput applications. With high carbon sensitivity, the probes deliver reliable measurements with very...

Micropipettes.(NEW Technology)
January 1, 2006... AccuPet Pro COLOR pipettes come in eight color-coded sizes. Designed to minimize the amount of hand stress over time, the lightweight units feature rubberized soft surfaces that help make pipetting more comfortable. Ergonomic handle design and...

cDNA clones.(NEW Technology)
January 1, 2006... The yeast shuttle vector pORF-CLONE is an intelligent method for an easy and cost-effective selection of clones containing long cDNA inserts with a correct open reading frame (ORF). The background of false ORFs can be significantly reduced,...

Tumor necrosis factor converting enzyme ELISA.(NEW Technology)
January 1, 2006... Human TACE/ADAM17 Quantikine ELISA kit is available. Tumor necrosis factor [alpha] converting enzyme (TACE) is a metalloprotease initially identified by its ability to cleave the membrane-anchored, 26 kDa form of TNF-[alpha] and release the...

Nanopositioning stage.(NEW Technology)
January 1, 2006... P-541 series nanopositioning scanning stages provide multi-axis motion to 120 x 120 x 120 [micro]m with resolution to 0.1 nanometers in a low profile package. They feature a large aperture. A parallel-kinematics flexure guiding system provides...

Whole Rat Genome Oligo Microarray.(NEW Technology)
January 1, 2006... With probes for more than 41,000 genes and transcripts, the Whole Rat Genome Oligo Microarray provides the genome coverage, validated genomic and sensitivity needed to assess the effect of environmental toxins or drug interactions on cells....

Automated Liquid Handling Workstation.(NEW Technology)
January 1, 2006... Sciclone ALH 4000 Liquid Handling Workstation integrates an automated liquid handler with the TWister II microplate handler into one easy-to-use system. Pre-programmed application templates for plate replication, serial dilution, assay set-up,...

Immersion coolers.(NEW Technology)
January 1, 2006... VLT Series immersion coolers offer three units that can be used to achieve low temperature capability with non-refrigerated circulators, or boost the cooling capacity of refrigerated circulators. Providing temperatures as low as -100 C, the...

ELISPOT Kits.(NEW Technology)
January 1, 2006... Human and Mouse IFN ELISPOT Kits, as well as a Starter ELSPOT Kit, are available from Pierce Biotechnology under the Endogen brand. The kits contain the components and protocol to develop 2 plates, and include 2 pre-coated 96-well membrane...