Bioscience Technology articles from January 2005

Bioscience Technology archives from January 2005

Premium standard.(Editor's Note)
January 1, 2005... Welcome to the new BioScience Technology. While the redesigned publication looks dramatically different than the issue you received last month, it is still everything it was, and more. The size has changed, that's true. I have heard this size...

Taconic opens Rockville facility.
January 1, 2005... Taconic has opened a Rockville, Md. facility, expanding to offer services including comprehensive animal health testing, biopharmaceutical safety testing and contract animal studies. The 13,500 square feet facility includes eight animal rooms...

Biolog collaborates with Nara Institute and Axiohelix to phenotype the E. coil genome.
January 1, 2005... Biolog, Inc. will use its Phenotype MicroArray (PM) technology to begin broad scale phenotyping of the E. coli genome, which consists of more than 4,000 genes. Phenotype MicroArrays allows efficient testing of hundreds to thousands of cellular...

Symphogen presents novel antibody isolation technology.
January 1, 2005... Symphogen A/S presented proprietary Symplex technology, which enables the isolation of truly human antibodies, at the IBC Antibody Engineering Conference in San Diego in December. The antibodies have very high affinity and the natural...

Perbio Science to market SoloHill microcarrier.
January 1, 2005... Perbio Science, a subsidiary of Fisher Scientific International Inc. (Pittsburgh, Penn.) has reached an agreement with SoloHill Engineering, Inc. (Ann Arbor, Mich.), through which Perbio will globally distribute and market SoloHill microcarrier...

Invitrogen Corp. and Illumina, Inc. announce collaboration.
January 1, 2005... Invitrogen Corp. (Carlsbad, Calif.) and Illumina, Inc. (San Diego, Calif.) have announced a collaboration that will expand Illumina's Oligator DNA synthesis technology and combine that capability with Invitrogen's sales, marketing and...

Accelrys launches Nanotechnology Consortium.
January 1, 2005... Enabling companies to bring nano-products to market more quickly and with reduced risk, Accelrys, Inc. (San Diego, CA) has announced the Accelrys Nanotechnology Consortium. The goal of the Consortium is to accelerate the development of software...

Spectral imaging system.(January's Technology)
January 1, 2005... DIGITAL ECLIPSE C1si confocal laser fluorescence microscope system can simultaneously acquire fluorescence spectra over a 320 nm range in wavelength at 10 nm spectral resolution, or over smaller ranges at 5 nm or 2.5 nm spectral resolution....

Laboratory animal studies injector.(January's Technology)
January 1, 2005... Laboratory Animal Studies Injector (LASI) is used to inject very small doses of a drug. Injections are initiated using a foot switch; one hand is free to hold the animal and the other is free to position the needle. The amount of drug required...

Digital X-ray module for imaging small animals.(January's Technology)
January 1, 2005... Digital X-ray imaging accessory for the Eastern Kodak Co. Scientific Imaging Systems' Image Station 200MM Multimodal Imaging System is a shielded enclosure that contains the x-ray source, associated controls and safety features. On-board high...

Stem Cell Antibody Panels.(January's Technology)
January 1, 2005... R&D Systems has added two new Stem Cell Antibody Panels to its line of stem cell products. Human Embryonic Stem Cell Marker Antibody Panel contains the antibodies anti-alkaline phosphatase; anti-Nanog; anti-Oct-3/4; anti-SSEA-1; and...

Silicon microarray technology for printing DNA and protein microarrays.(January's Technology)
January 1, 2005... Micromachined silicon toolset is offered for printing DNA and protein microarrays. This design improves pin-to-pin uniformity, eliminates pre-spotting, and reduces dead volume, carryover and 'missing spot' phenomena. This simple design,...

UV/Vis spectrophotometer measures microliter samples.(January's Technology)
January 1, 2005... Full spectrum UV/VIS measurements of one microliter samples are performed quickly by the NanoDrop ND-1000 Spectrophotometer. Sample is pipetted directly onto the measurement surface. Pathlengths of 1 mm and 0.2 mm allow for the measurement of...

Gene expression arrays.(January's Technology)
January 1, 2005... Eppendorf DualChip microarray systems are offered for gene expression analysis arid pathway identifications in toxicology, neuroscience, signal transduction and research on aging using human or mt models. Xmer technology based probes contain...

Microarrays: spotting the future.(Cover Story)
January 1, 2005... Microarray technology has come a long way since Affymax, predecessor to Affymetrix (Santa Clara, CA), introduced polypeptide arrays in the late 1980s. Today's gene, protein, and tissue arrays have evolved from research curiosities to the...

Polycarbonate culture flasks with vented caps.(Cell Culture, Analysis)
January 1, 2005... Sterile polycarbonate flasks can be auto-claved and are resusable. They are offered for shaker and suspension cell culture, are compatible with all cell culture media, reagents and buffers, and are virtually unbreakable. Virgin poly-carbonate...

Cell culture plate insert.(Cell Culture, Analysis)
January 1, 2005... BD Falcon 96-Multiwell Insert System is a cell culture insert platform suitable for both manual and robotic screening of compounds in cell-based assays. The system has been tested for its ability to produce a differentiated monolayer of Caco-2,...

Compact roller system.(Cell Culture, Analysis)
January 1, 2005... CELLROLL compact roller system, for the cultivation of adherent and suspension cells, can be used for cell studies, cultivationg, or for producing antibodies and recombinant proteins. Motor-driven ball-bearing rollers gradually and smoothly...

Digital color colony.(Cell Culture, Analysis)
January 1, 2005... The DigiCounter System uses a high-resolution color digital camera to instantly count bacteria and yeast colonies, and virus plaques. Agar assay plates up to 150 millimeters diameter can be read with defined areas included or excluded. Count...

Microplates for cell line growth.(Cell Culture, Analysis)
January 1, 2005... BactiGrowth contamination-free deep-well microplates are offered for growth of bacteria, yeast and mammalian or insect cell lines. The polypropylene plates eliminate the possibility of mold or polymer contaminates leaching out into samples....

New SteREO Lumar, V12 fluorescence stereomicroscope.(Advertisement)
January 1, 2005... Designed to provide exceptional performance for diverse applications in stereomicroscopy, SteREO Lumar has unrivaled fluorescence imaging capabilities equal only to light microscopy instruments. Developed for the highest fluorescence...

New TIRF (total internal reflection fluorescence).(Advertisement)
January 1, 2005... [ILLUSTRATION OMITTED] The TIRF fluorescence microscopy is an ideal tool for observation of rapid membrane processes, cell dynamics, single molecule events, vesicle and protein trafficking-even with very faint signals and extremely short...

New SteREO Discovery.V12, for non-fluorescence applications.(Advertisement)
January 1, 2005... SteREO Discovery integrates the same outstanding design for the highest performance in transmitted and reflected light microscopy. Impressive stability and exceptionally large specimen room, increased depth of field, excellent color...

Heavy wall filter flasks.(Cell Culture, Analysis)
January 1, 2005... Kimble and Kontes have upgraded all of their filter flasks, which now feature a heavier, more uniform bead for less chipping and maximum durability. Heavier walls mean less chance of breakage during vacuum filtration. Beaded bottoms increase...

Square media bottles.(Cell Culture, Analysis)
January 1, 2005... Sterile, flexible polyethylene terephthalate (PET) media bottles are offered for buffer and media storage. Available in 100 and 500 ml sizes, the bottles are clear, withstand multiple freeze thaw cycles, and are certified sterile,...

Large capacity flask.(Cell Culture, Analysis)
January 1, 2005... New 225 [cm.sup.2] NUNC EasYFlask is equipped with a system that allows opening or closing the flask by a mere one-third turn of the cap. Maximum airflow underneath the flask optimizes temperature equilibration during incubation, even when...

Optical imaging plate.(Cell Culture, Analysis)
January 1, 2005... New 384 well optical imaging microplate for high content screening is manufactured using a molding process that ensures flat well bottoms and well-to-well uniformity. The dimensional stability of this plate ensures that microscope refocusing is...

Dehydrated culture media.(Cell Culture, Analysis)
January 1, 2005... Criterion dehydrated microbiology culture media is formulated for solubility and milled for consistency. Four sizes str offered--2 ml Mylar zipper bag; 500 gm wide mouth bottle with finger grips; and 2 and 10 kg buckets. Over 100 standard...

Cell behavior monitor.(Cell Culture, Analysis)
January 1, 2005... ECIS Model 1600 (Electric Cell-substrate Impedance Sensing) measurement follows the impedance of cell-coated electrodes in real-time and is non-invasive and quantitative. The approach gathers date on cell behavior without the use of fluorescent...

Pre-poured agar plates.(Cell Culture, Analysis)
January 1, 2005... Pre-poured agar plates for use in molecular biology are packaged sterile and offer consistency from lot-to-lot. The line will include LB and LB Ampicillin Agar, as well as custom plates covering a range of media formulations and antibiotics....

Competent cells.(Cell Culture, Analysis)
January 1, 2005... ATCC has introduced E. coli competent cells and SOC Medium for researchers who utilize transformation in the study of gene expression, cloning, and other applications. GC5 and GC10 cells consistently show transformation efficiencies of >...

Mammalian cell counter.(Cell Culture, Analysis)
January 1, 2005... Accurately counting mammalian cells in under a minute, the NucleoCounter uses patented fluorescence technology and disposable cartridges pre-filled with a nuclei-staining dye to sample and analyze cell counts. The compact system is easy to use,...

Angiotensin Converting Enzyme ELISA.(Cell Culture, Analysis)
January 1, 2005... Human ACE Quantikine ELISA kit is available from R&D Systems. Angiotensin I Converting Enzyme is known for its role in blood pressure control and water and salt metabolism. ACE is also involved in immunity, reproduction and neuropeptide...

Basic media.(Cell Culture, Analysis)
January 1, 2005... MACS basic media line comprises RPMI and DMEM with classical formulations and modifications. Supplementation with vitamins, amino acids, cell growth factors, cytokines and serum allow adaptation for culture of specific cell types. Miltenyi...

Biomass Monitor.(Cell Culture, Analysis)
January 1, 2005... The entry-Ievel Biomass Monitor Model 210 provides a real-time record of the viable cell concentration, allowing users to see those critical process events. This instrument incorporates advances in RIT Impedance with in siru steam sterilizable...

Cell culture stirrers.(Cell Culture, Analysis)
January 1, 2005... Wheaton Science Products recently introduced the Micro-Stir and Biostir cell culture stirrer lines. The Micro-Stir is designed for cell culture applications as it has a stirring range of 5-175 RPM. The Biostir is more suited for bacteria or...

Disposable cell culture bag.(Cell Culture, Analysis)
January 1, 2005... Cellon CulturSil, high yield, disposable cell culture bag with modified/textured inner silicone surface, significantly enhances both cell number and productivity while providing excellent gas transfer. The bag provides approximately 20 times...

BioProcess container.(Cell Culture, Analysis)
January 1, 2005... Small Volume End-Ported BPC flexible bioprocess containers are manufactured of proprietary HyQ CX5-14 film, which demonstrates low gas permeability, a low profile of leachable compounds, and an animal-derived, component-free product contact...

Indirect ultrasonic processing produces high intensity.(Cell Culture, Analysis)
January 1, 2005... Cup Horns produce high ultrasonic intensity without probe intrusion. These accessories can process biohazardous samples without cross-contamination or airborne pollution. Up to 8 samples can be processed simultaneously. Water can be circulated...

Reduced serum media.(Cell Culture, Analysis)
January 1, 2005... Oibco Advanced D-MEM/F-12 and Advanced RPMI 1640 reduced serum media formulations enable researchers involved in mammalian cell culture to reduce Fetal Bovine Serum (FBS) supplementation by 50 to 90 percent with little or no change in cell...

Hollow fiber modules for cell culture scale-up system.(Cell Culture, Analysis)
January 1, 2005... FiberCell[R] Systems Duet[TM] hollow fiber modules are offered for cell culture scale-up for anti-body and recombinant protein production. The hollow fiber filters provide a large amount of surface area for cell attachment while concentrating...

Ultrafiltration device for cell harvesting.(Cell Culture, Analysis)
January 1, 2005... Pellicon XL tangential flow device can purify and concentrate from 300 ml to 2 liters of solution down to a final volume of 20 ml. Self-contained, with Luer connections for easy setup, the unit can be operated with either a peristaltic pump or...

Amplify mRNA from A single cell.(RNA Research)
January 1, 2005... TargetAmp Aminoallyl-aRNA Amplification Kit 1.0 reproducibly amplifies poly(A)-RNA isolated from 1 to ~ 50 cells (~ 10 pg to ~ 500 pg total RNA) by at least 5 million-fold. This simplified linear anti-sense RNA (aRNA) amplification method takes...

PCR filter plates.(RNA Research)
January 1, 2005... Drosophila RNAi Screening Center (DRSC) researchers at Harvard Medical School selected Millipore's size-exclusion MultiScreen PC[R.sub.96] filter plates for purification of double-stranded RNA (dsRNA). In their genome-wide study of gene...

Automated viral DNA and RNA purification.(RNA Research)
January 1, 2005... EZ1 Virus Mini Kit provides a fully automated procedure for simultaneous purification of viral DNA and RNA from serum, plasma, and cell-free body fluids, resulting in sensitive detection in downstream assays. The kit enables purification from a...

Microfluidic, automated electrophoresis.(RNA Research)
January 1, 2005... Experion automated electrophoresis system (Bio-Rad Laboratories) uses LabChip microfluidic technology (Caliper Life Sciences) to speed 1-D protein and RNA separation and analysis. A run typically lasts 30 minutes, including image analysis and...

siRNA transfection reagent.(RNA Research)
January 1, 2005... X-tremeGENE siRNA transfection reagent allows knock-down experiments with siRNA and co-transfection experiments using siRNA and DNA. The reagent requires no media changes and demonstrates minimal cyto-toxicity. It offers broad effectiveness on...

MicroRNA amplification and labeling for microarrays.(RNA Research)
January 1, 2005... Array 900miRNA microarray labeling kits are offered for use with microRNA, siRNA and other small RNA molecules (tRNA, 58 rRNA, nuclease fragments, etc). Proprietary 3DNA signal amplification technology produces accurate, validated results from...

One-step RT-PCR.(RNA Research)
January 1, 2005... RT-PCR Master Mix (2X) and FideliTaq RT-PCR Master Mix (2X) provide sensitive and specific, one-step RT-PCR reactions in a single tube. The ready-to-use mixes are available with Taq DNA Polymerase, optimized for routine detection, or FideliTaq...

Magnetic beads for gene expression studies.(RNA Research)
January 1, 2005... Dynabeads mRNA isolation products enable even the most difficult sources--including embryos--to be used to provide material suitable for downstream HTS gene expression studies. Based on superparamagnetic separation technologies, Dynabeads Oligo...

siRNA transfection reagents.(RNA Research)
January 1, 2005... DharmaFECT 1, 2, 3 and 4 siRNA transfection reagents (Dharmacon, Inc.) enhance transfection efficiency. The reagents are effective in a variety of cell types. This panel provides all the reagents needed to conduct RNAi experiments--siRNA...

Nucleic acid purification kits.(RNA Research)
January 1, 2005... DNA Research Innovations Ltd. has expanded its range of ChargeSwitch nucleic acid purification technologies. The kits avoid the introduction of known PCR inhibitors, such as alcohols, concentrated chaotropic salts or organic solvents. DNA...

Microarrays screen for RNA interference.(RNA Research)
January 1, 2005... Microarray products are offered for screening the efficacy of short-interfering RNA (siRNA) molecules in RNA Interference (RNAi) studies. Double-stranded siRNA molecules (typically 20-25 nucleotides in length) can be introduced into mammalian...

Cell Lysate kit, direct to PCR.(RNA Research)
January 1, 2005... Cells-to-Signal kit uses a chemical lysis method to create cell lysates in less than 5 minutes at room temperature. The cell lysate can be used directly for RT-PCR, bypassing RNA isolation altogether. The procedure is ideal for monitoring...

Gene expression profiling.(RNA Research)
January 1, 2005... GenUs BioSystems has launched a gene expression profiling service for picogram quantities of RNA. This service provides genomic data to researchers with limited sample amounts. Scientists often use techniques such as Laser Capture...

Tubes for RNA, DNA applications.(RNA Research)
January 1, 2005... Eppendorf LoBind micro-centrifuge tubes are optimized for genomic or proteomic RNA or DNA applications. Available in 0.5 ml, 1.5 ml and 2.0 ml sizes, the tubes feature a Safe-Lock lid and contain no DNase, RNase, human DNA or PCR inhibitors...

RNA amplification and labeling system.(RNA Research)
January 1, 2005... The Ovation Biotin System from NuGEN Technologies, Inc., for RNA amplification and labeling, is used for Affymetrix GeneChip arrays. The system enables expression analysis with as little as 5 nanograms of RNA starting material. Amplify RNA and...

RNAi target screening system.(RNA Research)
January 1, 2005... The BLOCK-iT RNAi family of products includes custom synthetic short-interfering RNA (siRNA), a Dicer system, a transfection kit and a transcription kit. This product suite will forward the understanding of genes and proteins by providing a...

Toploading balances.(Laboratory Equipment)
January 1, 2005... Excellence XS Toploader balance features the [MonoBloc.sub.HighSpeed] weighing cell, two microprocessors that accelerate measurement and reduce stabilization time by up to 20 percent. Fully automatic internal adjustment provides consistent,...

Benchtop centrifuge.(Laboratory Equipment)
January 1, 2005... The Beckman Coulter X-15R benchtop centrifuge spins the capacity 4 x 750 ml rotor at 5,250 xg and also spins microplate carriers. Adapters provide direct centrifugation of cell culture flasks, eliminating an entire step in the cell culture...

Class III glovebox.(Laboratory Equipment)
January 1, 2005... IsoGARD series Class Ill glovebox is designed for research involving agents assigned to BSL-3 or -4 facilities or where a high level of containment is required. The cabinets are well-suited for aerosolization studies, vaccine research...

Rotating mixer.(Laboratory Equipment)
January 1, 2005... Ecothern RT10 and RT11 rotating mixers can mix 50 0.50-ml and 48 1.5-ml centrifuge tubes with snap-on caps or screw-down caps in an end-over-end motion at speeds varying from 4 to 40 rpm. Accessory sample holders are available for 16 15-ml or 6...

Cleaning chemicals.(Laboratory Equipment)
January 1, 2005... LANCER-CLEAN Detergent and LANCERACID Rinse cleaning chemicals deliver optimum cleaning results for high-pressure glassware washers. Three different formulas are offered to clean everything from standard laboratory soils to hard-to-remove...

Temperature control circulator.(Laboratory Equipment)
January 1, 2005... Unistat 291w circulator offers efficient heating and cooling from -90 to 200 C. Manufactured by Huber, it has cooling capacities up to 19.0 kW with 24.0 kW of heating. The low-volume, hydraulically sealed unit controls temperature in a variety...

Multi-well plate evaporator.(Laboratory Equipment)
January 1, 2005... ZipVap Evaporator facilitates dry down of 96 and 384-well microplates. Needle height easily adjusts for 96 individual or 384 stainless steel needles. The unit holds standard microplates or deep well plates, and flow control is adjusted with a...

Class I safety enclosures.(Laboratory Equipment)
January 1, 2005... Purifier Class I Safety Enclosures provide protection from agents that require Biosafety level 1, 2 or 3 containment. Additionally, they serve as an economical alternative to Class II biological safety cabinets when applications do not require...

Ultra-low temp freezers.(Laboratory Equipment)
January 1, 2005... Upright ultra-low Forma PowerFREEZE ULT freezers are available in 11.6 to 20.2 cu/ft capacities. In-shelf cooling coilsincrease heat transfer efficiency. Thermo Electron Corp., 740-568-5741, www.thermo.com For information specific to this...

Refrigerators, environmental equipment.(Laboratory Equipment)
January 1, 2005... Nor-Lake Scientific offers a complete line of refrigeration and environmental storage equipment to meet the most demanding needs and specifications. Laboratory and pharmacy refrigerators and freezers, stability chambers, blood bank...

Compact laminar flow hoods.(Laboratory Equipment)
January 1, 2005... The Captair Flowcap 700S laminar flowfume hood is 29" wide x 24" deep. It delivers class 100 / ISO 5 HEPA filtered air to the work surface, creating a sterile positive pressure environment. Neither installation nor ductwork are required; the...

Oil-free vacuum pumps.(Laboratory Equipment)
January 1, 2005... Oil-tree LABOPORT vacuum pumps reduce operating noise levels using new materials, valve technology, and sound dampening techniques. Single-piece structured diaphragm offers long, reliable service. Vacuum is provided for rotary evaporators, gel...

Cryogenic preservation.(Laboratory Equipment)
January 1, 2005... LABS-20K, LABS-40K, and LAB-80K systems offer comprehensive and flexible cryostorage specimen preservation, and all models feature a unique and easily accessible turntable configuration. Taylor-Wharton/Harsco GasServ, 800-898-2657,...

Undercounter refrigerator.(Laboratory Equipment)
January 1, 2005... MediCool Model SR-L6110W refrigerator can be used under the lab bench or stand-free. The unit offers a temperature range of +1 to 14 C. Keyed door lock is standard, with optional padlock hasp. Forced-air circulation provides temperature control...

Variable speed orbital shaker.(Laboratory Equipment)
January 1, 2005... VSOS-4 heavy-duty orbital shaker offers a uniform motion that provides both mixing and vortexing. The smooth, quiet and reproducible shaking motion (19 mm circular) is available for applications such as cell/tissue culture, hybridization,...

Ductless Fume Hoods.(Laboratory Equipment)
January 1, 2005... Misonix Ductless Fume Hoods are self-contained carbon or HEPA filtered enclosures that remove hazardous fumes, vapors and particles. Control systems continuously monitor and display face velocity. Misonix, Inc., 800 645-9846, www.misonix.com...

Shaking water bath.(Laboratory Equipment)
January 1, 2005... Shaking water bath system combines temperature control with multi-motion, multi-speed sample agitation. The system consists of a 20 or 28 liter water bath, independent shaking platform, and special, polycarbonate, see-through cover. This...

Class II safety cabinets.(Laboratory Equipment)
January 1, 2005... Heraeus HERAsafe KS Class II safety cabinets feature a microprocessor-based control pad that is easily viewed, accessed and operated by any user in a seated position. Easy to clean and disinfect, the membrane keypad features prominent...

Tube rotator.(Laboratory Equipment)
January 1, 2005... MACSmix tube rotator runs on rechargeable batteries and operates. Suitable for use at temperatures of 2 to 42 C, it can be placed in a refrigerator or incubator. Miltenyi Biotec, 800-367-6227, www.MiltenyiBiotec.com For information...

Freezing bath facilitates freeze-dry process.(Laboratory Equipment)
January 1, 2005... VirTis Benchtop Shell Bath is a self-contained, compact freezing unit that produces a frozen product coating to the inside of freeze-drying flasks. This allows the freeze-drying process to be more efficient, permitting a greater volume of...

Laboratory incubators.(Laboratory Equipment)
January 1, 2005... Using forced air convection and cooling to 99.9C, Friocell incubators offer climate control, short recovery times and prevent samples from drying out. Lighting system esures homogenous parameters for growth conditions. Standard capacities are...

Hand-held homogenizer.(Laboratory Equipment)
January 1, 2005... Kinematica POLYTRON PT 12oo E hand-held homogenizer offers an ergonomic design that minimizes the stresses related to repetitive homogenization. The unit has a 100 W motor and fingertip speed control. Samples up to 250 ml are processed at...

Circulator program.(Laboratory Equipment)
January 1, 2005... Heating and refrigerating circulators in the Economy, TopTech, and HighTech series feature a warning system for low liquid level and 3-point temperature calibration. JULABO USA. Inc., 800-458-5226, www.julabo.com For information specific...

Shaking incubators.(Laboratory Equipment)
January 1, 2005... Incubators feature a lift-out shaker platform which accommodates a range of flask clamps, test tube racks, and a microtiter plate clamp. Four load-bearing positions are incorporated for optimal weight distribution. Counter-balanced weighting...

Advances in live cell imaging.(Application Note)
January 1, 2005... The Real Time Microscope (RTM) system provides easy access to images of living cells and organisms with maximum resolution, contrast and color fidelity. It causes minimum impact on the sample, and avoids the need for the normal techniques...

New LSM 5 LIVE, faster, more brilliant, more informative.(Advertisement)
January 1, 2005... The LSM 5 LIVE opens a new time window for confocal fluorescence microscopy. Its unique combination of superior scanning rate, outstanding image quality and exceptional sensitivity sets new standards in live cell imaging. With its high-res...