Bioscience Technology articles from December 2005

Bioscience Technology archives from December 2005

DNA repair and my dog.(EDITOR'S Note)
December 1, 2005... My dog has cancer. (It is safe to read on--at no time will the following item get sappy.) Actually, there are two dogs in the family, standard poodles named Ranger and Scout. Ranger is six years old; Scout is three and is the one who is sick....

ELS, UV, PDA chromatography detectors.(EDITOR'S Choice: DECEMBER'S TECHNOLOGY)
December 1, 2005... Waters Corporation has announced three detectors specifically designed for use with their ACQUITY Ultra Performance LC (UPLC) System. The photodiode array (PDA), evaporative light scattering (ELS) and tunable ultraviolet (TUV) detectors bring...

Physiological research microscope.(Brief Article)
December 1, 2005... The FN1 microscope exhibits virtually no electrical noise and vibration-free operation, and provides maximum open space for working around a specimen or whole animal with easy access to manipulators, stimulators and flow chambers. A new set of...

Monoclonal antibody for natural killer cell research.(EDITOR'S Choice: DECEMBER'S TECHNOLOGY)
December 1, 2005... IOTest Anti-IRp60-PE monoclonal antibody is offered for the identification of an inhibitory protein present on NK and dendritic cells. Because it is expressed on all NK cells as well as on a certain percentage of other cell types. IRp60 may...

Neural stem and progenitor cell growth kits.(EDITOR'S Choice: DECEMBER'S TECHNOLOGY)
December 1, 2005... NeuroCult kits provide long-term expansion and efficient differentiation of human neural stem and progenitor cells. The NeuroCult NS-A Proliferation Kit (Human) is serum-free and formulated for the long-term growth and efficient expansion of...

Slender, -86 freezer.(Brief Article)
December 1, 2005... Innova U360 freezer is 26.4" wide, including the handle. The unit incorporates noise-reducing technology, energy efficiency and intelligent on-screen messaging and diagnostics. Control system and large-character, backlit LCD displays system...

Genome Sequencer.(EDITOR'S Choice: DECEMBER'S TECHNOLOGY)
December 1, 2005... The Genome Sequencer 20 System can produce more than 20 million raw bases per 5.5-hour run on a single instrument. The software included with the system enables mapping or de novo assembly for whole genome shotgun sequencing of genomes up to 50...

Conjugation Kits, linkers.(EDITOR'S Choice: DECEMBER'S TECHNOLOGY)
December 1, 2005... SureFIRE Conjugation Kits, comprised of preactivated enzymes and linkers, offer a reliable approach to labeling proteins or antibodies. The kits provide all necessary reagents for labeling proteins with either alkaline phosphatase (AP) or...

The molecule: the big picture.
December 1, 2005... Despite the plethora of scientific buzzwords and that great waves of interest and hope often attach themselves to promising methodologies, picking trends that will shape the future of biology is no easy task. In this article we take a look at...

Discovery of biomarkers for endometrial cancer.(APPLICATION Note)
December 1, 2005... "To be able to detect cancer using biomarkers in a test, especially a blood test, is extremely attractive, because it means that you will be able to diagnose cancer, much more readily and in a less invasive manner" Dr K. W. Michael Siu, York...

Assay detects Tartrate-Resistant Acid Phosphatase 5b.(NEW Technology)
December 1, 2005... ELISAs are available for the detection of Tartrate-Resistant Acid Phosphatase 5b (TRACP 5b) in serum and plasma. Kits for human, rat and mouse forms of TRACP 5b detect TRACP 5b activity freshly liberated from osteoclasts. They can be used to...

Fluorokine MAP Assay.(NEW Technology)
December 1, 2005... R&D Systems has extended their line of human analytes for the Fluorokine MAP Multiplex Assay. For customization, the kits, in conjunction with a Human Panel B Base Kit, can be combined and multiplexed to examine the relative levels of several...

High-temperature silica column.(NEW Technology)
December 1, 2005... A silica-based stationary phase that withstands temperatures up to 200 C is incorporated in the [Blaze.sub.200] column. The column's polydentate silica phase is stable at extreme temperatures, with added pH as high as 12. The development of a...

Process, wash gels, blots, and slides.(NEW Technology)
December 1, 2005... Freedom Rocker uses a peristaltic pump to automatically transfer liquids into and out of trays on the rocker platform without the need for vacuum or gas connections. Offered for Southern, Northern, and Western blots, as well as for...

Ergonomic pipet tips.(NEW Technology)
December 1, 2005... These ergonomic pipet tips reduce the amount of force required to eject tips from the shafts of the Gilson, FinnPipette Digital, and FinnPipette Focus pipettors. A bi-fabricated wall creates a strong seal around the pipettor shaft. A small,...

Bulk tubing.(NEW Technology)
December 1, 2005... PumpSil platinum-cured silicon tubing is laser-marked end to end with part and lot numbers and use-by date, ensuring traceability. A 100% indelible fine etch is produced on the surface of the tube. Smooth bore controls protein binding and...

Imaging software suite.(INFORMATICS)
December 1, 2005... NIS-Elements imaging software suite optimizes the imaging process and workflow and provides the critical element of integrated information management for system based microscopy. The suite is composed of four distinct packages scaled to address...

Sequencing software, open access program.(INFORMATICS)
December 1, 2005... Invitrogen Corporation has announced the release of Vector NTI Advance 10. Centering on Vector NTI sequence analysis software, this new issue is the latest Windows version of the application. To coincide with the release, invitrogen is also...

Pathway analysis platform.(PathwayExpert)(Brief Article)
December 1, 2005... PathwayExpert is an enterprise class software platform for pathway analysis and systems biology, and allows researchers to analyze microarray and proteomics data, to create and share custom pathways for diseases, drug targets, biomarkers, and...

Protein identification software.(INFORMATICS)
December 1, 2005... BioWorks 3.2 protein identification software suite enables scientists and researchers to quickly and accurately identify proteins. The software supports Thermo Electron Corporation's entire range of Finnigan ion trap mass spectrometers. The...

Software screens for genotoxicity of potential drug compounds.(INFORMATICS)
December 1, 2005... The Micronucleus Formation Module, a software application for IN Cell Analyzer 1000 and 3000, allows screening for genotoxicity early in drug development. The micronuclei assay identifies DNA damage induced by genotoxic compounds and is...

High throughput screening data management.(INFORMATICS)
December 1, 2005... The release of the XE module for ActivityBase offers screening scientists a single environment for data capture, visualization, verification, quality control and storage. Independence from third-party spreadsheet packages enables XE to rapidly...

Microarray products referenced to NIH genomic data.(INFORMATICS)
December 1, 2005... Applera Corporation has announced that novel human, mouse, and rat genomic DNA sequence data are now freely accessible online through the National Center for Biotechnology Information NCBI), with Web links to corresponding ready-to-order...

Integration platform upgraded.(INFORMATICS)
December 1, 2005... Isentris 1.4, an upgrade to the Elsevier MDL Isentris informatics platform, supports a cohesive desktop research environment by integrating in-house and third-party applications. A growing community of companies, including Spotfire, InforSense...

Screening Automation solution.(INFORMATICS)
December 1, 2005... TERANODE Screening Automation, an informatics package for screening laboratories, provides assay automation, flexible assay design and real-time analytics. Leveraging TERANODE XDA (the company's Experiment Design Automation platform), the...

Non-destructive protein analysis.(PROTEOMIC REAGENTS, INSTRUMENTS)
December 1, 2005... Proteus protein analyzer system is based on Fourier transform infrared (FT-IR) technology and uses a Nicolet series FT-IR spectrometer to non-destructively scan protein samples for structural defect and impurity analysis, as well as process...

Protein separation columns.(PROTEOMIC REAGENTS, INSTRUMENTS)
December 1, 2005... HiTrap Butyl-S FF (1 ml and 5 ml) prepacked columns (GE Healthcare) enable purification or removal of highly hydrophobic proteins. HiTrap Butyl-S FF 1 ml column is included in the updated HiTrap HIC Selection Kit, which has been expanded to six...

Protein refolding kits.(PROTEOMIC REAGENTS, INSTRUMENTS)
December 1, 2005... Refold Master protein refolding kits work with all proteins using just one set of conditions. Non-detergent based reagents protect insoluble proteins during vulnerable stages in the refolding process. The reagents ensure these proteins can...

Protein membrane stain.(PROTEOMIC REAGENTS, INSTRUMENTS)
December 1, 2005... ProAct Membrane Stain, for the detection of proteins on nitrocellulose or PVDF membranes, is as sensitive as Ponceau S and provides fast results. The ready-to-use stain confirms transfer prior to Western blotting. It contains no harmful...

Ubiquitin Enrichment Kit.(PROTEOMICS)
December 1, 2005... Ubiquitin Enrichment Kit facilitates the isolation of polyubiquitin protein conjugates from cultured cells and tissue samples. The enriched fraction can be subsequently analyzed to determine the amount of general ubiquitin conjugates present or...

Cloning, expression service.(PROTEOMICS)
December 1, 2005... Contractexpress combines scientific expertise with a gene-to-protein suite of automation and sample management products, which perform and track molecular biology and protein expression processes. Service options include DNA sub-cloning,...

Single Protein Production System.(PROTEOMICS)
December 1, 2005... Introduced in living E. coli cells, the SPP (Single Protein Production) System exploits the properties of Maze a bacterial toxin that is an ssRNA- and ACA-specific endoribo-nuclease. Expression of this nuclease along with an engineered ACA-less...

Western Protein Standard.(PROTEOMICS)
December 1, 2005... MagicMark XP Western Protein Standard provides direct marker band visualization on Western blots. Each protein contains an IgG binding site, allowing marker visualization using the same antibody-conjugate reagents and protocol for the target...

Protein subfractionation.(PROTEOMICS)
December 1, 2005... SeraFILE 10 is a subfractionation methodology for differential proteome analysis. Electrophoretic profiles of serum subfractions demonstrate good resolution and quantification. Carryover from the three highest abundance serum proteins, albumin,...

Universal robotic system.(PROTEOMICS)
December 1, 2005... BioRobot Universal System can be used to automate a range of ready-to-run applications in 96-well format. Protocols are available for the purification of DNA and RNA, and for PCR and RT-PCR setup: Protein and sequencing applications will soon...

PCR System.(PCR)
December 1, 2005... The 9800 Fast PCR System provides results in a standard 96-well plate in approximately 25 rain. Consisting of the 9800 Fast Thermal Cycler, the GeneAmp Fast PCR Master Mix and the 96-well Fast Thermal Cycling Plate. the system makes convenient...

Multi-well plates for real-time PCR.(PCR)
December 1, 2005... Polypropylene 96-well and 384-well PCR plates offer high level heat exchange properties and precise dimensional tolerances. They are guaranteed DNase- and RNase-free, and non-pyrogenic. PCR products include an ABI-compatible, 96-well,...

Nano-scale RNA purification kit.(PCR)
December 1, 2005... ArrayPure nano-scale RNA purification kit provides the reagents needed to purify RNA from one or more eukaryotic cells, including quantities obtained with laser capture. The kit contains only aqueous solutions and requires no toxic organic...

One-step RT-PCR Kits for real-time, multiplex analysis.(PCR)
December 1, 2005... QuantiTect Multiplex RT-PCR Kits provide reliable quantitation of up to four RNA targets in a tube or well without optimization steps. Designed for gene expression analysis, the kits provide accurate quantification of the expression of target...